Circulation

RT/follows do not imply endorsement.

[Circulation @CircAHA]

Perioperative Anemia and Patient Blood Management in Cardiac Surgery
https://t.co/rD57X8HdvY

[Circulation @CircAHA]

Strategies for Optimizing Heart Failure Care in the Older Adult
https://t.co/5DU1H9p0Jm

[Circulation @CircAHA]

Co-published by @ACPinternists and @AHAScience #AHAJournals, @AnnalsofIMCC is a peer-reviewed, open access journal that publishes #casereports, case series, and image/video cases across the spectrum of medicine. Learn more and submit to AIMCC today at https://t.co/IzoNqdQ2Qo

[AHA Science @AHAScience]

The Cardiovascular-Kidney-Metabolic Syndrome Guideline will reshape CKM syndrome prevention and care.

[AHA Science @AHAScience]

The CKM Syndrome Guideline will shape how healthcare professionals approach prevention and care. Hear directly from the experts on translating it into practice.

Meet the experts who will unpack the science and discuss real-world applications at the upcoming live event.

@LisaVWMD @HeartDocSadiya @ambarkul @PowellWileyLab
@NutritionHF @ChiadiNdumele

[Circulation @CircAHA]

Defining Cardiovascular Endpoints in Oncology Trials: Challenges and Opportunities
https://t.co/IPXWyBbOQx

[Circulation @CircAHA]

ABYSS Trial Analysis: Higher resting heart rate predicts adverse events post-MI regardless of ejection fraction. β-blocker discontinuation raises heart rate by 10–13 bpm and worsens outcomes consistently across baseline heart rate tertiles https://t.co/MKCMuk3Ezi

[Circulation @CircAHA]

Endothelial SHMT2 drives pulmonary vascular remodeling via the SHMT2–BRISC–RhoB axis. Namodenoson inhibits this pathway with in vivo efficacy and an established clinical safety profile.https://t.co/jDF9LG3Jyl

[Circulation @CircAHA]

@manwanrong

[Circulation @CircAHA]

RND3 was identified as a novel mitochondrial matrix-resident small GTPase essential for energy metabolism homeostasis and normal cardiac function, with potential as a therapeutic target in ischemia-reperfusion injury.https://t.co/thuAKHQa1t

[Circulation @CircAHA]

@RonBlankstein
@AndrewEinstein7
@PanithayaC
@damini_dey
@buechelrr
@none
@Piotr_JSlomka
@CardioMDPhD
@attilafehermd
@DanielMHuck

[Circulation @CircAHA]

In a multicenter PET registry, patients with no evidence of flow-limiting CAD and discordantly low subendocardial myocardial flow reserve (MFR) had an increased risk of MACE than those with normal transmural & subendocardial MFR. https://t.co/jd8O5TIHnj

[Circulation @CircAHA]

@jingyan

[Circulation @CircAHA]

Mutations in Notch transcriptional coactivator MAML1 directly recapitulated VSDs in models.
Dysregulation of liquid-liquid phase separation impaired Notch signaling, establishing link between condensate dynamics & congenital disease. https://t.co/9aNXNNC3D2

[Circulation @CircAHA]

Alternative splicing of Tropomyosin 1 (TPM1b) exon 9a is a pathogenic mechanism in myofilament disorder and diastolic dysfunction in HFpEF and is mediated by SRPK3. This may represent a novel therapeutic target for HFpEF.https://t.co/vSPCP57Xea

[Circulation @CircAHA]

@chesterleedrum
@meekelee
@Fruberto
@MicroscopyCluster
@LUCASLU
@rsyf2

[Circulation @CircAHA]

Loss of STMP1 perturbs mitochondrial cristae and drives cellular inflammation, heart failure and cardiac aging. https://t.co/DkbHkJ2FM9

[Circulation @CircAHA]

@BiomagMfb
@SMART18617738

[Circulation @CircAHA]

HIF-2 drives coronary inflammation, remodeling, and thrombosis in a novel mouse model recapitulating Kawasaki disease. Pharmacological HIF-2 targeting may be a new therapeutic strategy for coronary vasculitis. https://t.co/BvBGjXCdpS

[Circulation @CircAHA]

@abetemidayo

[Circulation @CircAHA]

Common African ancestry-enriched variants of uncertain significance associated with increased cardiomyopathy and arrhythmia risk, particularly in individuals with CV risk factors or HF. https://t.co/JcqzeQjj2z