Caity Holmes

Caitlyn Holmes. Incoming Assistant Professor at the U of Minnesota studying Klebsiella-host interactions. Postdoc: Bachman Lab. Alum: UW-Madison, UCF. #KlebClub

[Caity Holmes @CL_Holmes]

An Update! 🎉 I am so happy to announce that in May 2025, I will be joining the University of Minnesota as an Assistant Professor in the Department of Microbiology & Immunology. My lab will study host-pathogen interactions during Klebsiella systemic infection.

[Caity Holmes @CL_Holmes]

Thank you to all collaborators for helping to sort through this huge set of data and to the barcoding community for your help in comparing our trends to other systems! This is truly a study were I made friends and collaborators along the way. ⭐

[Caity Holmes @CL_Holmes]

I'm excited to announce our latest publication! We teamed up with @KHullahalli to barcode Klebsiella and ask basic questions about bacteremia pathogenesis: 1) how are bacteria shared between sites and 2) which host and bacterial factors influence dynamics?
https://t.co/Ajdjyu0QUX

[Caity Holmes @CL_Holmes]

Klebsiella leaves the lung in two distinct patterns, termed "metastatic" and "direct", which are defined by the extent of clonal replication in primary tissues and predict bacterial burden across sites. Oxidative stress from the host and bacterial LPS influences these patterns.

[Caity Holmes @CL_Holmes]

It's that time of year! Registration and abstract submission for the 6th Klebsiella Seminar Series is now open. Participation is free and abstracts are due by February 16th. See the link below for details:
https://t.co/vOKIxqXJas
#KlebClub

[Caity Holmes @CL_Holmes]

@tomstantonmicro 💪

[Caity Holmes @CL_Holmes]

@FleemanLab Beautiful!!

[Caity Holmes @CL_Holmes]

@minisciencegirl Thank you, Amy! That is so kind. The STAMPR work has been a fun thought exercise in how infections progress and how bacteria need to adapt to spread between tissues. Certainly a huge collaborative effort!

[Ruth 룻 Isenberg, PhD @RuthlessRuth15]

I'm so happy that this paper is finally published! This one was a long time coming: 9 years, 3 pairs of hands, 270 strains, 93 plasmids, and a lot of hard work. It started as a side project that eventually led to my entire dissertation, and I'm glad it did.

[Caity Holmes @CL_Holmes]

@KhaderShabaana Tips for personnel management would be helpful! For example, how to set group/individual expectations, handle conflict between lab members, or conduct annual reviews. It would be nice to hear a few different strategies for these types of things since everyone does it differently.

[Caity Holmes @CL_Holmes]

New article!✨In this review, we present a broad overview of bloodstream infections, consider microbial pathogenesis mechanisms, and discuss how these strategies could be used in future therapies. #KlebClub

[Nature Reviews Microbiology @NatureRevMicro]

Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention

Holmes, Bachman & co. explore major pathogens causing bloodstream infections, their pathogenesis, opportunities for prevention, diagnosis & treatment options.

[Caity Holmes @CL_Holmes]

@MGoBacteria I am feeling pretty strongly that "born" is fine, but am willing to entertain arguments to the contrary.

[Caity Holmes @CL_Holmes]

@EB_Hirsch 🤩

[Klebsiella Club @KlebClub]

#KlebClub planning is back in session with our TWO NEW MEMBERS!!! Make sure to send a big congrats to Juan Valencia and @tomstantonmicro!!

[Caity Holmes @CL_Holmes]

@jlewillett 🙌 yes yes yes to this

[Caity Holmes @CL_Holmes]

@SunMicrobe @KlebClub @MGoBacteria So great to see you this weekend Yuang!

[Caity Holmes @CL_Holmes]

@MGoBacteria @FleemanLab @OlayaRendueles @KlebClub @GordonConf @az1980micro Rooting for you, Ammar!! Thanks everyone for the well wishes 🥹

[Caity Holmes @CL_Holmes]

@FleemanLab @MGoBacteria @OlayaRendueles @KlebClub @GordonConf @az1980micro Thank youuuuu!

[Caity Holmes @CL_Holmes]

@OlayaRendueles @MGoBacteria @KlebClub @GordonConf @az1980micro Stuck in Boston! There were big outages at airports. Ammar and Jay made it to NYC though!

#FreeCaity

[Klebsiella Club @KlebClub]

Great @GordonConf for #KlebClub! Safe travels to all, especially those dealing with flight delays and cancellations!

[Caity Holmes @CL_Holmes]

❤️🦠🙌💅 Great science and great friends!

[Klebsiella Club @KlebClub]

#KlebClub spotted in the wild! It was a beautiful day for a hike at @GordonConf with @az1980micro, @CL_Holmes, @KHullahalli, and @VornhagenLab!