Christian Pallasch

Clinician scientist in hematology/oncology at the University Hospital of Cologne #UKKoeln (Department for Internal Medicine, Hematology and Oncology)#CECAD

[Christian Pallasch @CPallasch]

We are excited to share our new paper in #Bloodjournal from the Pallasch lab at #UKKoeln: Izquierdo et al. “Extracellular vesicles and PDL1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies” 1/10
https://t.co/C2nG11zNTa

[Christian Pallasch @CPallasch]

Nice data from the Tammela lab...

[Tuomas Tammela @TuomasTammela]

Several years in the making (and aging), @Xueqian_Zhuang 's study on aging is out today @Nature. She finds, surprisingly, that aging suppresses tumorigenesis and stemness in the lung by promoting a functional iron insufficiency in the alveolar epithelium. https://t.co/kKbQc2hMSf

[Christian Pallasch @CPallasch]

@schumacherbj Wow, congratulations!

[Björn Schumacher @schumacherbj]

🧠🧠🧠Could the brain influence evolution? Check out our super hot preprint: A single pair of neurons that sense temperature controls genetic changes in the inheritable genome by triggering transposons that change the genome for generations to come
https://t.co/vGWsTHDPo5

[Allerbiomics @allerbiomics]

December comences with news at #ScienceShareMondays. This new study led by @CPallasch and Anna Beielstein as first author, delves into macrophages metabolism at lymphoma and gathers contributions from @IzquierdoAlv_E, @ALMAVILLASEOR2 and @metabolomicaceu https://t.co/HIRPPGNGNK

[Christian Pallasch @CPallasch]

7/7 Read the full article here:
https://t.co/CYolbLX5cr
We're excited about the potential implications for improving cancer treatments and will continue to address immune metabolism in cancer!

[Christian Pallasch @CPallasch]

1/7 Exciting news! Our lab's recent research is now published in @CellRepMed! 🎉🧬
"Pentose Phosphate Pathway Inhibition activates Macrophages towards phagocytic Lymphoma Cell Clearance"
https://t.co/CYolbLX5cr
#CancerResearch #Immunotherapy #Lymphoma

[Christian Pallasch @CPallasch]

6/7 Special thanks to our collaborators for their invaluable contributions:
@CoralBarbasAr
@HallekMichael
@WinkelsLab
@IzquierdoAlv_E
Your expertise and support were crucial to this research.

[Christian Pallasch @CPallasch]

Exciting new W2-Professorship position at the University Hospital of Cologne in Experimental Cardio-Oncology.

Please apply, tell friends and co-workers and contact me for any further questions...#UKKoeln #UniKöln #UniCologne

[Gianmaria Liccardi @Giammy_L]

A fantastic #sfb1530 retreat: great projects and discussions that generate new ideas and collaborations. Thank you @HallekMichael for organizing this and for leading this amazing consortium. #lymphoidmalignancies #dlbcl #lymphoma #dfg #crc1530

[ESH (Haematology) @ESHaematology]

📣 #ESHLYMPHOID2023 starts this Friday - it's your last chance to REGISTER ➡ https://t.co/H7msA3tCdI
7th Translational Research Conference
LYMPHOID MALIGNANCIES
🗓️ October 20-22, 2023 in Estoril 🇵🇹
Chairs: @HallekMichael, Georg Lenz, @SehnLaurie, @LouisStaudt
#ESHCONFERENCES

[Björn Schumacher @schumacherbj]

This is the most disgusting and appalling thing I have seen in our country in recent times. We must confront today's antisemitism for which our society should not have the slightest tolerance be it homegrown or imported.

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

[Christian Pallasch @CPallasch]

PPP seems to be key regulator and targetable modulator of macrophage activity in lymphoma. We propose a feasible approach to improve efficacy of antibody based immunotherapies

[Christian Pallasch @CPallasch]

Immune metabolism determines lymphoma microenvironment and therapy effects - see our labs latest preprint: "Pentose Phosphate Pathway Inhibition activates Macrophages towards phagocytic Lymphoma Cell Clearance" https://t.co/t2MhKdQWZT

[Christian Pallasch @CPallasch]

In vivo PPP inhibition rewired macrophage maturation and activation. Addition of the PPP inhibitor S3 to therapeutic antibody therapy achieved significantly prolonged overall survival in an aggressive B-cell lymphoma mouse model.