C. Scott Gallagher

[C. Scott Gallagher @CScottGallagher]

Variant Bio Launches Company-Wide Carbon Offset Program by Leslie Hepner https://t.co/rMxvggYjNg

[C. Scott Gallagher @CScottGallagher]

In Variant Bio's most recent blog post, my colleague Paloma Guzzardo describes her recent experience at a "virtual conference" in a very sobering context: https://t.co/JvggjdDP5G.

[C. Scott Gallagher @CScottGallagher]

A Novel Finding in Colombia Could Unlock New Tools in the Fight Against Alzheimer’s Disease by Gabrielle Bertier https://t.co/w5MPzduuxi

[C. Scott Gallagher @CScottGallagher]

Check out VariantBio's latest blog post by one of my great colleagues, Sarah LeBaron von Baeyer, PhD: "An Anthropologist’s Perspective on COVID-19: Q&A with Dr. Adia Benton" https://t.co/NYBxzrLlrv

[Philip N Cohen @familyunequal]

Unimpressed by your scatterplot? Boost your correlation from .23 to .97 by putting the data in fewer bins. https://t.co/rSfqdoAvvd

[C. Scott Gallagher @CScottGallagher]

Amazing work in the UKBB illustrating how horizontal pleiotropy impacts genetic architecture of many human phenotypes. #bioRxiv #UKBB https://t.co/8lrXlorlGd

[Konrad Karczewski @konradjk]

The gnomAD preprint is out! We aggregated 125,748 exomes and 15,708 genomes into a public resource of >240M high quality variants, available at https://t.co/Gr5SW9v3A0 (1/5). https://t.co/EYb5pFzkp1

[Casey Brown @casey6r0wn]

Significant inflation of ‘mendelian’ mutation effect size appears quite common. Beautiful genetics from @mnweedon! I’ve already added it to my syllabus for next year. https://t.co/VwtEohjveA

[Kaitlin Samocha @ksamocha]

An update to the pLI/constraint work: LOEUF ("loss-of-function observed/expected upper bound fraction"). This is a more direct measure of effect size since it measures the actual depletion of expected LoFs.

[Alon Keinan @AlonKeinan]

A timely, thoughtful, and extensive review/perspective on mechanisms underlying sex differences in complex diseases and other traits

By @eakhram, Davis, & @be_stranger (@UChicago; @VUMChealth)

@NatureRevGenet
#Genetics #Genomics #GWAS #QTL #eQTL #ChrX
https://t.co/60Fiss1snj

[Alicia Martin @genetisaur]

Update! A revised version of our preprint is up now: https://t.co/vTsqH4Hyo4. Biggest changes: we compare polygenic risk score accuracy across global population in UK Biobank, we assess prediction accuracy for five diseases here + Biobank Japan, and text re: evening imbalance.

[Kevin Mitchell @WiringTheBrain]

Yes! Small samples generate false positives. And idea that a result from an under-powered study is somehow STRONGER evidence that it must be real, is completely false.

[Lionel Page @page_eco]

Great animation to see that trying to look for meaning in small samples' differences is often staring at random noise.

Raincloud plots with sample size N=50 (left) and N=200 (right). No difference between the two conditions.

By @ajstewart_lang

[Senator Bob Corker @SenBobCorker]

I never thought I’d see the day a White House would moonlight as a public relations firm for the Crown Prince of Saudi Arabia. https://t.co/MQ4JsoQtqk

[Yang Luo @yluo86]

amazing resource from @LudeFranke lab. cis- and trans-eQTL analysis in blood from 31,684 individuals. summary stats https://t.co/I83FMMPUxp; preprint https://t.co/yhIOBFlRW4

[monix M.Sc. (master of schenanigans) @willowescapee]

When I stare at the MBTA map too long, all the lines start to look like weird dragons

[C. Scott Gallagher @CScottGallagher]

Fascinating work showing estimates of the heritability of aging may be attributed to assortative mating. #genetics #aging https://t.co/D2YlMY1ITZ

[bioRxiv @biorxivpreprint]

Detection of rare disease-related genetic variants using the birthday model https://t.co/krFgq4SQFd #bioRxiv

[bioRxiv @biorxivpreprint]

Exome sequencing identifies high impact trait-associated alleles enriched in Finns https://t.co/esrMyxA9uG #bioRxiv

[Nature Genetics @NatureGenet]

Distinguishing genetic correlation from causation across 52 diseases and complex traits https://t.co/1Wse712wuc