You have power over your mind – not outside events. Realize this and you will find strength by M. Aurelius about COVID. Dermpath25 @ColumbiaDerm @EmoryPathology
I am excited to announce our next @ISIMMweb webinar scheduled for Wednesday, May 20 at 11 am ET.
Sarah Chiang (@MSKpathology; renowned for major effort in GYN mesenchymal tumors) will present "Cracking the Code of GYN Mesenchymal Tumors."
Register here: https://t.co/oz2dSDv0FW
👇🛑 Dermatofibroma: start above the lesion — epidermal induction is the clue.
👀 Look up first: acanthosis
🎨 Pigment clue: basal hyperpigmentation over the lesion
🌱 Induction pattern: follicular/adnexal buds may mimic a superficial bcc tumor
🎯 At the edge: collagen trapping helps seal the diagnosis
#dermpath #dermatology #dermatologia #dermtwitter #pathology #pathologists #pathTwitter
We are excited to launch the new @pathologyCast website:
🌐 https://t.co/YuEvyboogA
A modern, Netflix-style platform for pathology education featuring:
🔹 300+ lectures
🔹 Global expert speakers
🔹 100% free
Built to make pathology learning easier to explore, and enjoy
.
🔬 VZV / herpes zoster: never gets old — like Chanel, it’s timeless!
🎈 Ballooning degeneration of keratinocytes
🧩 Acantholysis with intraepidermal vesicle/ulcer
👥 Multinucleated keratinocytes with nuclear molding
🔵 Steel-gray nuclei / chromatin margination ± Cowdry A inclusions
🧬 Follicular/adnexal involvement can be a helpful clue for VZV
Key differentials 🔍
🦠 HSV — histologically very similar; if you were told they can separate them on H&E --> that is fake news! HSV/VZV IHC
🧴 Spongiotic/contact dermatitis — vesicles + eosinophils, but no viral cytopathic effect
🐜 Arthropod bite reaction — wedge-shaped infiltrate, eosinophils, no herpetic nuclear changes
💊 Fixed drug eruption / PLEVA — necrotic keratinocytes and interface change, but no multinucleation/Cowdry inclusions
#dermpath #dermatology #dermatologia #dermtwitter #pathology #pathologists #pathTwitter
Let’s start the morning with pressure lesions! This one is rare but worth knowing—it's much more common on the ear.
🛌Chondrodermatitis Nodularis Nasi (CNN):
👃 Painful, tender small nodule on the nasal tip/ala
⚠️ Central ulcer with wedge-shaped dermal ischemic degeneration
🧩 Underlying degenerative cartilage-chondrocyte dropout/fissuring
🔄 Pressure-induced ischemic repair pattern with granulation tissue — histologically identical to Chondrodermatitis nodularis helicis
#dermpath #dermatology #dermatologia #dermtwitter #pathology #pathologists #PathTwitter