Carolina Alvadia

[Valeria Kalienkova 🇺🇦🌻 @VKalienkova]

I was often asked what I was working on in @CPaulino_ group. Well, here it is! 🥁🥳 What a fascinating combination of ion channel and secondary active transporter domains in one protein! Great teamwork with @MartinPeter91
@rheinbergerj
https://t.co/zsEpMrUMEj

[Carolina Alvadia @CarolinaAlvadia]

@VKalienkova @CPaulino_ @MartinPeter91 @rheinbergerj Congratulations V! So happy to see this published! 🤩

[Carolina Alvadia @CarolinaAlvadia]

@seegerlab @Prolatium Congrats Imre! 👏🥳

[Carolina Alvadia @CarolinaAlvadia]

Very elegant approach for cryo-em of membrane proteins! 👏

[bioRxiv @biorxivpreprint]

Time-resolved cryo-EM of G protein activation by a GPCR https://t.co/sF6H7H8cEt #bioRxiv

[Basile Wicky @BasileWicky]

An insane success rate for the direct generation of protein binders against 4 biological targets! 18% of the 384 designs bound (Kd<10uM), with the best hits being double-digit nM (straight out of the computer, no opt.)

[Carolina Alvadia @CarolinaAlvadia]

@RamanadaneK @DutzlerLab @MelanieArndt96 Thank you Karthik!! 😊

[Carolina Alvadia @CarolinaAlvadia]

Very happy to share the final paper of my PhD at @DutzlerLab! Together with @MelanieArndt96, we used electrophysiology, cell-base scrambling assays and cryo-EM to investigate the elusive mechanism of TMEM16F activation.
https://t.co/TzuwxtGFrj

[Joël Bloch @Joel_S_Bloch]

Cryo-EM structure of a voltage-gated ion channel in polarized vesicles. Super cool work from my colleague Shiva in the MacKinnon lab!
https://t.co/apljfHzqyq

[Martin Pacesa @MartinPacesa]

The @befcorreia lab is looking for a postdoc! As a postdoc there myself, I can tell you that Lausanne is a stunning city, EPFL has a strong collaborative environment, and the lab researchis super exciting! On top of that, Bruno is a really chill dude 😎 https://t.co/JkF42PlNNh

[Structura Biotechnology @structurabio]

❄️⚡️#CryoSPARC v4.0 Beta is now publicly available! 🚀 
In v4.0 we’ve built a brand-new, super powerful user interface! Visualize, curate & process #cryoEM data like never before. Plus, many algorithm & software updates.
Read more & watch: https://t.co/M3mLGtFPIq
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[Carolina Alvadia @CarolinaAlvadia]

@MartinPacesa @Nature @MartinJinek Congrats @MartinPacesa! 🤩

[Carolina Alvadia @CarolinaAlvadia]

@CPaulino_ @ResearchGbb @MembraneEnzymo1 Parabéns Cristina! 🤩

[Carolina Alvadia @CarolinaAlvadia]

Wait what?

[Patrick Moynihan @pmoyniha]

This is conceptually insane. https://t.co/GUhltCdt0l

[Carolina Alvadia @CarolinaAlvadia]

@cell_club Congrats @accardilab, great work!

[Fyodor Urnov @UrnovFyodor]

This stunning paper describes a tryptophan to phenylalanine substitution phenomenon that is remarkable.
The authors’ restraint in not describing this W to F process using the acronym that immediately comes to my puerile mind is no less remarkable. 🤓
https://t.co/1UZ01EFIjg

[Valeria Kalienkova 🇺🇦🌻 @VKalienkova]

Most of you are probably aware of this. My home country is being dragged into war by Putin's Russia. If you would like to #SupportUkraine here is what you can do. No such thing as contribution too insignificant! Тримайся, Україно! ✊🇺🇦 #UkraineRussiaCrisis #IStandWithUkraine

[Carolina Alvadia @CarolinaAlvadia]

🤯

[Carolina Alvadia @CarolinaAlvadia]

@GpcReid Some available now :)

[Structura Biotechnology @structurabio]

❄️ Just in time for the holidays: #cryoSPARC v3.3 is now available! ⚡
New 3D classification (BETA), auto-tuning blob picker, Ewald sphere & anisotropic magnification correction, performance improvements, bug fixes, and more for #cryoEM processing! https://t.co/M3mLGtFhSS