Recently guest editing a Special Issue of Life, an open access journal by MDPI (https://t.co/QZ5iKA7EpQ), dedicated to experimental and computational G Protein-Coupled Receptors (GPCRs) medicinal chemistry https://t.co/AqnDYue6XU
#GPCRs#medicinalchemistry#drugdiscovery
We are still recruiting for this position, as well as a couple of more junior ones. While I am flattered that postdocs are poached after a few yeas in @Filizolalab1, I can't keep pace with all required job advertisement. Please help RT.
"Oltre tremila adesioni alla petizione popolare per la difesa dei Ficus di Viale Trieste a Cagliari. | Gruppo d'Intervento Giuridico odv" https://t.co/iEkasdavZo
New research from @AkashDeepBiswas & @scuolanormale colleagues reports that L-DOPA & Droxidopa have the same hydrogen bond binding sites on the β2-adrenergic receptor (β2 AR) as endogenous agonists such as adrenaline, noradrenaline, & dopamine
https://t.co/BLThZF8v1N
Lowest energy conformations of protonated adrenaline from the molecular docking into (A) rigid (yellow) and (B) flexible (green) β2AR models are compared to the conformation of the ligand in the β2AR X-ray crystal structure (PDB ID: 4LDO) (dark green).
(left) X-ray crystal structure of the active state of Human Beta 2-Adrenergic Receptor (β2AR) bound to adrenaline (green) (Ring et al. 2013, Nature, 502:575–579) (right) lowest energy conformations of neutral (yellow) and protonated (orange) adrenaline from redocking calculations
I will be presenting a poster at the 65th Biophysical Society Annual Meeting on February 24, 2021 from 2 to 3:30 pm USA Eastern Time
ANALYSIS OF L-DOPA AND DROXIDOPA BINDING TO HUMAN BETA 2-ADRENERGIC RECEPTOR #BPS2021 https://t.co/qnunhaDDgU
hearts in the kitchen ❤💙 nel disordine: torte di castagne e di marroni, preparazione della torta di marroni, torta di patate dolci ed insalata 💚❤ @ Pisa, Tuscany, Italy https://t.co/AW3qeJT2d6