CDD press

SCIENTIFIC JOURNAL group by @SpringerNature Cell Death & Differentiation, Death & Disease, Cell Death Discovery

[Dimitris_Kanellis @Di_Kanellis]

https://t.co/g1fAxWNFze.

Happy to see our work published in @cddpress. We show that JP-1302, a BBB-penetrant α2C-adrenergic receptor antagonist, inhibits rRNA synthesis at low concentrations, while engaging TOP2 and broader chromatin-disruptive mechanisms at higher doses!

[CDD press @cddpress]

🎗️ Liver Cancer Awareness Month 🎗️

Browse our collection of research papers focused on liver cancer in:
Cell Death & Disease
https://t.co/8S8yWW4UFU
Cell Death Discovery
https://t.co/Pud297MHiS
#LiverCancer #CancerResearch

[CDD press @cddpress]

“Anthracycline and antimetabolite, trigger distinct resistance mechanisms in TP53mut AML”

Read this latest Correspondence in Cell Death Discovery ⤵️
https://t.co/zoHgNlDjsa

[CDD press @cddpress]

🎗️ Breast Cancer Awareness Month 🎗️

Access our updated collection of breast cancer-related research papers in:
Cell Death & Disease
https://t.co/s7jEn8SMfh
Cell Death Discovery
https://t.co/SyiWRGztwl
#BreastCancer #BreastCancerAwarenessMonth #CancerResearch

[Ivano Amelio @ivanoamelio]

And at Cell Death Discovery (@CDDpress), we are also interested in sharing high-quality research that has led to negative results.

If you have rigorous and informative findings that deserve visibility, please reach out.

[CDD press @cddpress]

“Efferocytosis triggered proteomic reprogramming of macrophages reveals CD97 as a novel apoptotic receptor”

@drbenraymond & @TrostLab identified CD97 as a novel #Efferocytosis-associated protein ⤵️
https://t.co/PnM407Vp1X

[CDD press @cddpress]

“Galectin-3 restrains T cell-driven inflammation in the testis and epididymis”

This study advances the understanding of the mechanisms underlying immune-mediated male #Infertility ⤵️
https://t.co/UC80m4QMkd

[CDD press @cddpress]

“DDX3X regulates DNA repair pathway choice at double-strand breaks via RNA-DNA hybrid formation”

This work highlights a new mechanism controlling #DNARepair and tumor cell sensitivity to #chemotherapy ⤵️
https://t.co/jjRBP8A6nl

[CDD press @cddpress]

“Hepatitis B virus protein X promotes survival and loss of hepatocyte identity in a differentiated human liver organoid system”

This physiologically relevant organoid model clarifies longstanding questions about the pathogenesis of #HBV-associated #HCC ⤵️
https://t.co/ORSBPI0qdC

[CDD press @cddpress]

🌏International Cell Death Seminar Series - Edition #2🌏

Details:
📅Date: Wednesday 14th October 
🕰️Time: 4:30pm AEDT / 8:30am CEST
💻Webinar link: https://t.co/8h5odvery8

See the flyer below for more information ⤵️

[CDD press @cddpress]

"MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA"
https://t.co/nijBoxOyOz

[CDD press @cddpress]

“The expanding MDM2 universe”

Fresh off the press: an editorial by Prof. Engeland about the recently uncovered connection between MDM2 and #InnateImmunity ⤵️
https://t.co/3e043t1eKf

[CDD press @cddpress]

“Immunoregulatory role of quercetin in lung cancer”

Quercetin exerts potent #Antioxidant, #AntiProliferative, and #Immunomodulatory effects ⤵️
https://t.co/YZXmyE5VgZ

[CDD press @cddpress]

“Cuproptosis in iron overload hepatocytes”

Copper as a potent and previously underappreciated modifier of iron-induced cellular injury ⤵️
https://t.co/PTksM7FEQ8

[CDD press @cddpress]

“PGC1α-mediated upregulation of PHD2 represses HIF-signaling, limiting prostate cancer progression”

PGC1 represses HIF signaling via ERR-driven EGLN1 transcriptional induction, expanding its #TumorSuppressive role in #PCa ⤵️
https://t.co/nd57x9Ot4D
@fagomaider

[CDD press @cddpress]

“MIC13-linked cristae disruption causes metabolic failure and early fibrotic remodelling in mitochondrial liver disease”

An #iPSC-derived hepatocyte model to investigate MIC13-associated mitochondrial #hepatopathy ⤵️
https://t.co/O1tMkoSdNG

[CDD press @cddpress]

Blocking cancer lipid synthesis can trigger a distinct #Senescence program ⤵️

[JAVIER A. MENENDEZ @metabostemness]

Fatty acid synthesis therapy-induced senescence (FASTIS) exhibits a molecular signature distinct from the TIS programs triggered by DNA-damaging agents or CDK4/6 inhibition including a poorly inflammatory but highly immunomodulatory #SASP

https://t.co/f2f7P5hI9i

[CDD press @cddpress]

“SMC1A is required for fate determinations of human spermatogonial stem cells and male fertility by interacting with YBX1 and stabilizing HMGA2 mRNA via an m5C modification”

Potential genetic markers and therapeutic targets for #NOA ⤵️
https://t.co/Zhls0zlVyg

[CDD press @cddpress]

"ATP synthase subunits e and g are essential for Ca2+ homeostasis and development in Drosophila melanogaster independent of oxidative phosphorylation"

Researchers at @dsb_unipd uncovered a novel role for ATP Synthase in #Ca2+ homeostasis in #Drosophila ⤵️
https://t.co/4vaGt9KwsT

[CDD press @cddpress]

“Recognition and management of acute relapse of multiple sclerosis, neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody-associated disease”

Check out this recent review in CDD ⤵️
https://t.co/fy8mUPhuuI