Death on the Beach: Cell Death & Disease
32nd ECDO Conference
📍Favignana, Italy
🗓️ 16-19 September 2026
📌 Abstract submission deadline: 30 June 2026
More info: https://t.co/7APWpdsRaP
Preliminary programme: https://t.co/FeZ0NF4b10
@ECDOorg#CellDeath#Conference
“EGFR deletion in myeloid cells reprograms the immunosuppressive landscape of colorectal cancer”
A groundbreaking multi-omics study from @CCR_SibiliaLab reveals EGFR in specific myeloid cell subsets as a potential new therapeutic target in mCRC ⤵️
https://t.co/copfy9tTE6
“Akt-mediated RALY phosphorylation functions as a molecular switch governing c-Myc stability”
Researchers uncovered the oncogenic RALY–USP22–c-Myc signalling axis and developed a therapeutic peptide that effectively suppresses tumour growth ⤵️
https://t.co/A7dubM2IhJ
“NF-κB inducing kinase (NIK) deletion accelerates KRAS-driven pancreatic cancer in association with tumor microenvironment remodeling”
Read more about this non-canonical NF-κB pathway in PDAC pathogenesis ⤵️
https://t.co/Mu16yuMFut
“Mitochondrial calcium uptake drives organelle remodeling to promote inflammasome-dependent cytokine release”
A mechanistic insight into the intersection between mitochondrial function and innate immune activation ⤵️
https://t.co/gZiR7F7R9d
“GSDME acts as an epigenetic modifier to promote melanoma development via centriole biogenesis regulator PLK4”
An intriguing oncogenic role for GSDME beyond its canonical pore-forming function in pyroptosis ⤵️
https://t.co/FhbF8YVsjS
“Fatty acid channelling into triglycerides and oxylipins drives ferroptosis resistance during oncogenic BRAF-induced senescence”
An interesting link between lipid metabolism in OIS cells and their resistance to ferroptosis and oxidative stress ⤵️
https://t.co/NPtzzYh7z9
“The E3 ubiquitin ligase Itch plays an essential role in kidney fibrosis by inhibiting Dvl2/GSK3β/β-catenin signaling pathway”
A comprehensive investigation into the protective role of the E3 ligase Itch in kidney fibrosis ⤵️
https://t.co/H93UDQYyJ5
“LSM7 coordinates scaRNA-mediated snRNA modification to ensure spliceosome fidelity and spermatogonial stem cell differentiation”
Mechanistic insights into post-transcriptional control of male germ cell development ⤵️
https://t.co/ISLw15kBsT
“Transcription-coupled nucleotide excision repair protects against genomic instability and cell death induced by the liver toxin methyleugenol”
Read how TC-NER, rather than GG-NER, is crucial for resolving ME-induced DNA lesions ⤵️
https://t.co/YDlPFoIJ5l
“Bon appétit, your phagocyte”
New perspective in CDDiscovery on how apoptotic cells undergo a meticulous ‘meal preparation’ process to be optimally suited for consumption by professional and non-professional phagocytes ⤵️
https://t.co/WenzadEhdd
“CCR7 orchestrates the malignant progression of memory B cells in MYC-overexpressing lymphoma”
Learn how CCR7 directs memory-B-cell trafficking from draining LNs to distal LNs and coordinates microenvironmental support to promote progression ⤵️
https://t.co/AOcABRQ2ML
“A neutrophil-intrinsic CKLF1–PKM2 axis drives glycolytic flux for de novo DAG synthesis and pro-inflammatory ROS production”
The proposed neutrophil-targeted nanotherapeutic approach opens a new avenue for immunometabolic intervention in stroke ⤵️
https://t.co/v0pUjlQueC
“Dual targeting of chemoresistance and ferroptosis in gastric cancer: DDR1/VEGFR2 inhibitor K-13 synergizes with docetaxel from preclinical models to phase Ib/II clinical trial”
A promising therapeutic strategy for late-stage GC patients ⤵️
https://t.co/DmuMI4GbNk
“Fibroblast-mediated KRAS activation in double-negative prostate cancer”
CCL2–FGF–KRAS signalling as a potential therapeutic target for treating AR-independent prostate cancer in late-stage DNPC ⤵️
https://t.co/CtrWkDBCQK
“m6A-mediated CABLES1 translation potentiates tumor radioresistance via facilitating nonhomologous end-joining repair”
Discover how CABLES1 inhibition may synergize with existing cancer therapies ⤵️
https://t.co/ybVyXYnTHo
“USP4 modulates ZBP1 ubiquitination to regulate microglial PANoptosis and functional outcomes following traumatic brain injury”
These findings identify USP4 as a promising therapeutic target for TBI treatment ⤵️
https://t.co/Dzc9DLKdWO