Charles Winterhalter

@wellcometrust Early Career Fellow working on bacterial DNA damage repair @CBCB_Newcastle @UniofNewcastle.
@winterhalterlab.bsky.social

[Charles Winterhalter @Ch_Winterhalter]

Still time left to apply and join my team on a fully funded PhD project investigating dynamics of the bacterial DNA damage response in live cells using microscopy & genomics

[Charles Winterhalter @Ch_Winterhalter]

Excited to share with you the story that enabled me to start my own lab: what happens when the bacterial DNA replication machinery encounters single-strand discontinuities on template DNA? What is required for DNA break repair and replication restart? https://t.co/6TpedBjudf

[Lis Lowe👩🏼‍🔬 @Lis_Lowe]

Come and do a PhD with me and @DrPaulJamesUK to find some new exciting enzymes! #glycotime

https://t.co/d35dheS6Sf

[David Grainger @GraingerLab]

If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)

[Charles Winterhalter @Ch_Winterhalter]

Navigating through academia as an ECR can be challenging. @CKYLau and @CorreiaMeloC will tell us more about their experience of becoming group leaders and how to achieve this on 12th Feb @BiochemSoc. Free registration at
https://t.co/1SGc9FTvXS

[Dmitry Ghilarov @dghilarov]

Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date).

@JohnInnesCentre @DurhamU34989 @MCB_UJ

[Achillefs Kapanidis @AchillesKap]

2 weeks to go! Apply for the 2 posts by Nov 25th - pls RT!

[Charles Winterhalter @Ch_Winterhalter]

@AKTooke @foster_lab @steverenshaw @becky31290 @JosiePyrah @MM_Sheffield @unmc Well done! Hard work always pays off!

[Amy Tooke @AKTooke]

Happy to share this story from my PhD @foster_lab & @steverenshaw - with @becky31290 in Ken Bayles’ lab & @JosiePyrah - we show that oxacillin & tetracycline display synergy against S. aureus biofilms & during infection in zebrafish!
@MM_Sheffield @unmc
https://t.co/mc2lVSMY1i

[Charles Winterhalter @Ch_Winterhalter]

Fully-funded @DiMeN_DTP PhD opportunity available in my lab to investigate novel DNA damage repair processes using next generation sequencing and microscopy techniques (co-supervised by @acdarby & @MicKasia). Please RT and contact me if interested.

https://t.co/7a9TYDiHNl

[Foster Lab @foster_lab]

We are very excited to announce our latest work on how MRSA conquers antibiotics. We show that high-level resistance to methicillin requires S. aureus to utilise an alternative mode of cell division to ensure its survival! @Sheffield_AFM @Olulana4

https://t.co/y2UcirhNZN…

[Universities UK @UniversitiesUK]

As well as improving our daily lives, university research contributes £54 BILLION to the UK economy and supports 121k jobs across the UK📈

If we want to be a country fit for the future, the government must make research funding more sustainable👇

https://t.co/W8d5vxiXDx

[Tung Le @Tung_BK_Le]

DTP PhD studentship available in our lab. Start: Oct 2025. Apply: now-24th Nov 2024

Taming the Viral Wolf: Cracking the Code of Gene Transfer Agents in Bacteria.

Please RT. Thank you!!!

https://t.co/09BTekK6un

[Charles Winterhalter @Ch_Winterhalter]

If you haven't already, check out the Hachiman phage defence system characterised by the @doudna_lab @CellCellPress. Inspiring work and scary 'phantom' cells (perfect for Halloween!) 👏
https://t.co/p3Z3IVtwQv

[Susan Schlimpert @SusanSchlimpert]

Please RT. 1x postdoc and 1xPhD position available in our group to study the role of NLR-like proteins in cellular development and antibiotic production in Streptomyces.

Postdoc: https://t.co/1dxVBIizvm
PhD position: https://t.co/W8DjdW3Brd

Email me for more information.

[Charles Winterhalter @Ch_Winterhalter]

Super nice Single Molecule Bacteriology meeting in the Cotswolds. Thanks to the organisers, looking forward to new collaborations and see you at the next event!

[Biochemical Society @BiochemSoc]

That's a wrap on the 91st Harden: Single Molecule Bacteriology event!
Huge thanks to everyone who joined us for insightful talks, lively discussions and lots of fun! #biochemevent

[Charles Winterhalter @Ch_Winterhalter]

Looking forward to day 2 at the UK DNA Replication Meeting for more amazing talks! Come and find me this evening at Poster 4 to hear all about replisome arrest and replication restart from nicks @BiochemSoc #BioChemEvent

[Charles Winterhalter @Ch_Winterhalter]

Registration for the Single Molecule Bacteriology III conference is open, I am honoured to be invited speaker and looking forward to meet you all there!

[andre nussenzweig lab @nussenza]

A high-resolution view of how replication-coupled DNA breaks are generated, processed and repaired. Congrats to @pavani_raphael, @TripathiVeenu, and many terrific collaborators including @FrogWalterLab, @CejkaLab, @weiwsmiling. See https://t.co/HjXVyHWIWE

[Dmitry Ghilarov @dghilarov]

A rewarding collaboration revealing an entirely novel inhibitor pocket in DNA gyrase. Inhibition mechanism determined via beautiful biochemistry experiments by @leela_bg - well done Leela! Thanks to @yushuv @AstburyCentre for the final EM data collection 👍