Chelsea E Macpherson, PhD, PT, DPT, NCS

🇨🇦 PhD & Doctor of Physical Therapy, specializing in #Neurorehabilitation for #MovementDisorders and #NeuromuscularDisorders. DPT&PhD @Columbia Postdoc @WUSTL

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

🤗 The time has come my dear friends! I’m officially moving over to @Bluesky, so if you’re on there say hello! https://t.co/a7qEIPkHub

See you all soon! ❤️

[Michael Okun @MichaelOkun]

Do infections cause Parkinson's disease? Mercado and colleagues present a compelling new review in the Journal of Parkinson's Disease. My take: There is increasing evidence that pathogens may play a role in triggering or in contributing to some (many) cases diagnosed as 'synucleinopathy.' How? Infection leads to inflammation. Then, we must next consider whether a genetic variant (i.e. a PD gene) is present or absent. Finally, there will emerge both a clinical phenotype and a biological subtype. Remember, post-encephalitic, PINK1, PARKIN and LRRK2 may all be (biologically) synuclein negative. Also, we must consider whether you are a susceptible host? The authors present a clear way to ponder a potential role for infections in Parkinson's disease.
https://t.co/Yts2BvdB9D @ParkinsonDotOrg @FixelInstitute @journal_PD #Parkinsons

[Eric Topol @EricTopol]

How does exercise and fitness promote healthy brain aging?
An outstanding, comprehensive review @TheLancet
reduced neuroinflammmation, preserves blood-brain-barrier, neurogenesis, role of exerkines, and much more
https://t.co/7Wy3o1KE6o @AtefeTari @UWisloff @CERG_NTNU @NTNU

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

Two of my past mentors in one talk? 🤩 What a force! Looks like an incredible event for those interested in learning about Neurodegenerative conditions! @LoriQuinnNY @TerryEllisPT

[Neurorehab Lab at TC, Columbia Univ @NeuroRehabLabTC]

New webinar 📣

Join us for an upcoming free webinar featuring @LoriQuinnNY and expert colleagues as they discuss recent updates in physiotherapy for Parkinson’s Disease and Huntington’s Disease! @APTANeuroPT @JNPT

🔗 Register at: https://t.co/8NQr7BHg4e

[Eric Topol @EricTopol]

How does sleep protect against neurodegenerative disease? A review @NeuroCellPress
https://t.co/wmHKMrCjoo

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

Such upsetting news. As someone who has most of their research in the #telehealth space with rare conditions, it has provided access to many who are unable to receive necessary and or specialized care within their local community.

[Ro Khanna @RoKhanna]

What is the rationale for this other than making life more difficult for many seniors?

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

Thankful to have the opportunity to present some of my dissertation work from the PRIME-RCT pilot trial earlier today at #APTACSM platform session! Wonderful presentations all around!#ataxia #PhysicalTherapy #telehealth

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

Day 1 #APTA #CSM2025 pre-con event was a success! We held a live lab in conjunction with the Houston Area #Parkinson’s Society so PT’s/PTA’s could practice implementing the PD clinical practice guidelines in real time! Thank you to all who participated 🥰

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

On my way to Houston,TX for #APTA #CSM2025 can’t wait to see everyone!

[Cochrane @cochranecollab]

📚 Statistical errors in meta-analyses can impact the reliability of systematic reviews. This new article highlights the most frequent mistakes and how to avoid them.

📖 Read it here: https://t.co/2YSWWGwa6M

#SystematicReviews #MetaAnalysis #ResearchMethods #Statistics

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

I am analyzing several populations & their upper limb movements. I asked to look at how I move in comparison for my own understanding. So, I’ve got bilateral actigraph sensors on my wrists for the next few days. Excited to check out the result! #postdoc

[Broadway for Ataxia Foundation @BFAtaxia]

Join us this upcoming January 16th at 6:30 pm EST for our first free BFA session of the year! We cannot wait to celebrate and connect with all of you!! #ataxia #broadwayforataxia #communitybuilding #singinganddancing 🩷

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

✨ Happy New Year! ✨ Wishing you all a brilliant 2025! We got to it and stepped into the new year with a #walkwithdad for #cardiachealth and #brainhealth ❤️🧠 🥳

[APTAAcademyofNeuroPT @APTANeuroPT]

6️⃣ Clinical Practice Guidelines & 6️⃣ Outcome Measure Recommendations. As we count down to 2025, we’re spotlighting the essential resources that drive evidence-based practice. Let’s step into the new year with knowledge and impact!
#APTANeuroPT #CPGs #OutcomeMeasures

[Broadway for Ataxia Foundation @BFAtaxia]

Join us next Thursday, December 19th at 6:30 pm EST for Broadway for Ataxia's free monthly zoom session. We will have a lot of fun exercises for patients with Ataxia so please stop by! 🩵 #broadwayforataxia #singinganddancing #community #ataxia #fun

[Beth Crowner @crownerb]

Neuro PT’s: interested in an evidence based course that includes a HANDS ON LAB with people with Parkinson Disease?
Consider attending this CSM pre-conference course with members of the
PD Knowledge Translation Taskforce!

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

@BobbyHandPT @WUSTL Thanks Bobby, you are too kind! Welcome back to twitter! 🤗

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

Week 1 of my #postdoc @WUSTL is officially in the books! I am incredibly grateful to be here. Im learning so much, and I am simply in awe of everyone around me. Thank you for such a warm welcome to St. Louis! Looking forward to what the future holds ☺️

[Chelsea E Macpherson, PhD, PT, DPT, NCS @ChelseaMacDPT]

Find yourself using the same interventions? Unsure about how you should apply the Parkinson Clinical Practice Guidelines? Come to our pre-con with LIVE LAB! 🧠 let’s get moving @APTAcsm @APTANeuroPT

[APTAAcademyofNeuroPT @APTANeuroPT]

As you plan your trip for CSM 2025, consider adding a day to attend this ANPT pre-con, which starts on Wednesday, February 12, 2025, 8:00 am - 5:00 pm.

Early Bird registration ends November 6, 2024. Find information on the APTA website: https://t.co/T5c6XXuLyM
#APTANeuroPT #APTA

[Broadway for Ataxia Foundation @BFAtaxia]

On Thursday, November 21st at 6:30 pm EST we are having our free monthly session! Please join us for an evening of fun, lots of singing, and community building. We hope to see you all there! 🩶 #broadwayforataxia #ataxia #singinganddancing #JoinUs

[Michael Okun @MichaelOkun]

It may seem counterintuitive, but what if you treated Parkinson's fatigue with some exercise? Ann-Kristin Folkerts and colleagues did just that in a new paper @journal_PD.
Key Points:
- Fatigue is common and can be debilitating.
- The authors zeroed in on randomized controlled trials.
- 14 drug and 16 non-drug studies were examined.
- Modafinil compared to placebo: non-significant effect on fatigue.
- Physical exercise in 8 studies had a small significant effect.
- Acupuncture no effect (but not a lot of data).
My take: First, I love the idea that if you are fatigued, trying some exercise therapy may be a 'counterintuitive' way to derive some benefit(s). Second, if you are fatigued w/ your Parkinson's, don't forget to address sleep first, and perhaps get a tracking device and look toward 6+ hours of sleep a night (not just being present in bed!). Have someone check out your medication list as sometimes, less is more. Finally, do not shy away from a formal sleep study and a sleep expert, as this can be helpful and sometimes apnea will need to be treated both for fatigue, but also to reduce heart related effects of this sleep/breathing disorder. It is early days for exercise, and these studies were small and thus will need replication and a better understanding of how to tailor exercise to help an individual with Parkinson's related fatigue.
https://t.co/Jk66elWQrr #Parkinsons #fatigue #sleep