ChemBioNAC

Chemical Biology and Nucleic Acid Chemistry Group at #IBMM @umontpellier @chimiebalard Group leader @Smietana_M

[Michael Smietana @Smietana_M]

Excited to share our new paper in Nature Communications in collaboration with @OBasle !
We report the first artificial metallo-photoDNAzyme enabling highly enantioselective visible-light photochemistry via a DNA-embedded iridium photocatalyst.
https://t.co/CilVycEGeW

[ChemistryEur @ChemistryEur]

Proximity-Induced Ligation of Noncomplementary Oligonucleotides Triggered by Charge-Transfer Interactions by Francois Morvan, Michael Smietana, and co-workers (@Smietana_M) #OpenAccess
https://t.co/xlEyF5abhe

[JCIM & JCTC Journals @JCIM_JCTC]

When the Position of Pendant Groups Makes the Difference in G-Quadruplex Behavior: The Case of Bis-Conjugated Thrombin-Binding Aptamers #Aptamers
https://t.co/4nx3k6k5UO
@Smietana_M @ChemBioNAC @orozco_lab @DanielaMontesa9 @umontpellier @IRBBarcelona
#JCIM Vol66 Issue1 #compchem

[Michael Smietana @Smietana_M]

📢DNA templates are no longer required for efficient nucleic acid ligation.
💡We introduce Charge-Transfer Assisted Ligation (CTAL): a new templated reactivity based on π-stacking donor–acceptor interactions (DAN/NDI), not base pairing.
📄 Open access: https://t.co/o7U8tEYzdv

[Debart Françoise @DebartFrancoise]

@ChemBioNAC @CNRSchimie Merci à @CNRSchimie, @umontpellier de m’avoir offert un super environnement pour exercer 40 ans de recherche dont 36 exercées au @CNRS qui ont abouti à une carrière dont je suis fière. Un grand merci à mes étudiants, ingénieurs qui ont largement contribué à ma réussite.

[Debart Françoise @DebartFrancoise]

@ChemBioNAC @CNRSchimie Mes sincères remerciements vont à l’équipe @ChembioNAC pour avoir organisé mon pot de départ entre collègues et amis. Une nouvelle page se tourne pour moi vers des activités différentes mais le flambeau des ARN modifiés et coiffés est entre de bonnes mains pour durer et réussir🤞

[ChemBioNAC @ChemBioNAC]

We were delighted to celebrate the retirement of @DebartFrancoise, closing a remarkable chapter and opening a new one.
It was a warm and heartfelt moment, reflecting her dedication and the positive impact she has had on all of us over the years.
Thank you Françoise!
@CNRSchimie

[Andrea Rentmeister @RentmeisterLab]

Had a great day visiting @DebartFrancoise and Michael Smietana at IBMM in Montpellier. 😊 Thank you for the invitation, the hospitality and the scientific discussions. 🧬🤩

[Michael Smietana @Smietana_M]

Our lastest article has just been released (Org. Biomol. Chem): Synthesis, duplex-forming properties, and enzymatic resistance of oligonucleotides containing N-acylsulfonamide linkages https://t.co/e4yMN25Xzy
@CNRSchimie @umontpellier @enscmchimiemtp @ChemBioNAC @IBMM_Balard

[EuroBoron10 @eu10boron]

🎇Please meet our next 10th Euroboron invited speaker - Michael Smietana🎇

Michael is Professor at the University of Montpellier, France.

His current research focuses on molecular recognition and nucleic acid bioconjugates, in particular boron-modified nucleic acids.

[Michael Smietana @Smietana_M]

Very pleased to share our latest publication on the Synthesis and Base-Pairing Properties of Oligonucleotides Containing 5′-(R)- and 5′-(S)-C-Aryl-thymidine now in JOC https://t.co/cS0sBPbXA3
@DebartFrancoise @VasseurJeanJacq @HausdorffMarcel @CNRSchimie @umontpellier @ChemBioNAC

[Michael Booth @DrMikeBooth]

We have developed an entirely new mechanism of action for gene knockdown -> trafficking of targeted mRNAs to the lysosomal, using lysosomal trafficking oligonucleotides (LyTONs)!

Published in @ChemicalScience

Led by @disha_kashyap_, with @milnetom68
https://t.co/ciaFGwt5QG

[Michael Smietana @Smietana_M]

Kudos to @PastorelZachary and Juliette Zanzi
Great Team work with @OBasle @CanacYves @arseniyadis @elisejdumont and Alessio Bartocci
@CNRS @umontpellier @IBMM_Balard @ChemBioNAC @LCC_CNRS @NiceChemistry

[IBMM - Institut des Biomolécules Max Mousseron @IBMM_Balard]

🚨 Looking for a stimulating environment where your expertise in chemical biology can shine ? The Institute IBMM invites applications for 2 CNRS tenure-track positions.
-> Glycochemistry
-> RNA Chemistry
contact : [email protected]
To apply : https://t.co/jJYAfL15vL

[Hollenstein group @Hollensteinlab]

Very happy to share out new pre-print on the enzymatic GalNAc-labelling of oligonucleotides. Big congrats to undergraduate student Elisa and graduate student @pierrenicolas_b !
https://t.co/EIoFinvP7L
@institutpasteur @CNRSchimie

[IBMM - Institut des Biomolécules Max Mousseron @IBMM_Balard]

🚨 Looking for a stimulating environment where your expertise in chemical biology can shine ? The Institute IBMM Balard invites applications for two CNRS tenure-track positions.
-> Glycochemistry
-> RNA Chemistry
Contact : [email protected]

[Michael Smietana @Smietana_M]

Very special scientific day on the occasion of @VasseurJeanJacq retirement. Thanks to the speakers for their great lectures and thanks to all the participants. Happy retirement Jean-Jacques !🌴☀️🚴
@umontpellier @ChemBioNAC @IBMM_Balard @Philippe_Auge @PascalDumy

[G. Berionni Group University of Namur @Dr_Berionni]

Fantastic lectures on photo-biocatalysis, transition-metal catalysis and organocatalysis at @UNamur chemistry department. Great dissussions with @GrimaudLaurence (ENS Paris), @Smietana_M (Univ Montpellier @ChemBioNAC), E McGarrigle (@McGarrigleGroup, UCDublin) and @OlivierRiant.

[G. Berionni Group University of Namur @Dr_Berionni]

Mini-symposium this Friday at the chemistry department of @UNamur. Three invited speakers: Prof. Smietana (@Smietana_M), Grimaud (@GrimaudLaurence) and McGarrigle (@McGarrigleGroup). Looking forward to welcome you and talk about chemistry!

[Chemistry Europe @ChemEurope]

#EurJOC Recent Development of DNA-based Biohybrid Systems Driven by Light (Michael Smietana and co-workers) @Smietana_M @OBasle @Chembionac • https://t.co/VzmQrW9B06