These are the small companies and research groups @CARB_X supports at global scale. Not one or two, but dozens at a time. They need both money and scientific, business, and technical help turning ideas into products
Good morning, #AAIC24 attendees! Are you ready to kick off an exciting week of sharing new ideas and discoveries? Scientific sessions start soon. Get today’s schedule at https://t.co/jdq5rM0vbg.
@EugeneFreedman On the broadcasts I'm still looking for home plate lady and Geddy in their usual seats.. but I will say the live seating experience is better IMO
The pharma industry invents medicines that ease suffering & save lives. So why are we so bad at communicating the value being generated? From @PeterKolchinsky https://t.co/nhdX9E9nzp
What's now for the Amyloid Hypothesis in #Alzheimers?
Several recent studies using monoclonal antibodies show evidence that removing aggregated Aβ from the brains of symptomatic patients can slow the disease progression.
Yes, despite the clinical benefit of these trials still being modest, disease-modifying treatments for Alzheimer's are feasible, and they are going to happen more consistently within the next few years.
I and others are focusing on understanding how soluble amyloid species, not senile plaque or large fibrils, can play a crucial role in synapse loss and neurodegeneration in Alzheimer's.
Oligomeric amyloid, for example (🔵 in the image below), triggers extensive glial activation (🟠astrocytes) in the human brain. By using promising antibodies and optimizing the timing for therapeutic intervention, we might be finally close to helping patients with Alzheimer's and similar neurodegenerative diseases.
A scary photo for an optimistic #FluorescenceFriday
@TaoofStieb Sadly, the sun is insufficiently massive to go supernova so we don't even have that to look forward to... we'll just get engulfed in a dying red giant. But I appreciate the sentiment.
To say antimicrobial resistance (AMR) is a problem is an understatement. If nothing changes, by 2050, 10 million AMR-related deaths are expected to occur every year. Explore our resource page to learn about AMR, & how we can combat it. https://t.co/tcYObiQPww #WAAW#USAAW23
Capping off a successful #BIOEUROPE by uncapping some traditional Bavarian fare! A great conference all around, thanks to all who met up while I was in Munich to speak about @Treventis_corp