$HGEN @humanigen
Plz fill up below table and perform sun-analysis ASAP!
1.If there's significant difference in SOC group according to Hx. of vaccination, then there must be the bias factor to assess the effect of Lenz. (1/2)
$HGEN
Let the new games begin!!
In a viewpoint of an investor, recent market cap of $HGEN looks hilarious.
Considering the value of #Lenzilumab, this stock price means that of Black Friday.
In spite of many worries, I still believe in #Lenz.
https://t.co/gqoOpkfGA4
@humanigen $HGEN
If cytokine storm doesn't happen to patients' body, the effect of #Lenzilumab isn't able to work as we expect.
COVID-19 vaccine is well-known as preventing severe symptoms such as hypoxia. So vaccination must help good prognosis of SOC group. (2/3)
$HGEN @humanigen
Hx. of COVID-19 vaccination or not should be divided and re-analyzed SOC group vs. Lenz group using ACTIV-5 patients' data.
Theoretically, #Lenzilulmab is a GM-CSF inhibitor and designed to suppress cytokine storm. (1/3)
@humanigen $HGEN
My humble suggestion to the company, @humanigen is to perform sub-analysis on the negative effect of vaccination during ACTIV-5 and to appeal to NIH and FDA after meaningful results excluding vaccination bias. (3/3)
$HGEN @humanigen
If the survival rate of control group in ACTIV-5 is found superior to prev. Remde studies, how can we interpret that?
At least, #Lenzilumab should be chosen if less complications than SOC group at the same condition.
#Lenzilumab instead of corticosteroid.
$HGEN @humanigen
My quick suggestions to the company
1. Plz perform sub-analysis of ACTIV-5 data considering vaccination and survival benefit of #Lenz ASAP.
2. Plz find co-operative partnership for COVID-19 Tx. ASAP.
3. Plz hurry up SHIELD study.
4. Plz hang in there!
@humanigen
If sub-analysis is feasible, vaccination history should be considered and re-assessed as an important factor.
Personally speaking, all approved COVID-19 Tx. including Remdesivir should be re-assessed their effect after COVID-19 vaccination.
That must be fair. (2/2)
$HGEN
I think
before COVID-19 vaccination era, #Lenzilumab was really helpful to severe hypoxic patients.
But after vaccination, severe hypoxia might become somewhat controllable with only SOC.
My guess is that's one of the reasons why ACTIV-5/BET-B failed. (1/2)
$HGEN
Even though ACTIV-5/BET-B failed, at least we gained the precious data about the safety of #Lenzilumab from it.
It's time to turn our focus on the basic mechanism of GM-CSF inhibitor for the Tx. of cytokine storm during CAR T-cell Tx.
$HGEN
In the real field, severe COVID-19 cases are being reported consistently in spite of vaccination.
To make matters worse, many experts are worrying about the appearance of new variants and an unprecedented resurgence in fall.
But I'm not afraid.
Cuz we have #Lenzilumab!!
As of today, to all $HGEN investors,
it doesn't matter who tweets or likes.
The only thing which matters is the successful TLD of Activ-5/ BET-B.
Don' t feed anything to whom emphasizes his or her descriptive analysis of sp or deny insider's tweet.
I believe in #Lenzilumab!!
$HGEN
To someone, it seems to be so weird because @humanigen advertises other company.
It's so understandable. But to me, this twit seems to be so meaningful because successful $EIGR's outcomes are related to the mechanism of action of #Lenzilumab. (1/3)
@humanigen Considering the fact that single-dose Peginterferon Lambda works really well as the treament of COVID-19 patients, #Lenzilumab would show desirable outcomes for the treatment of moderate-to-severe COVID-19 pts., too. (2/3)