🚨 Why can obesity make weight loss harder?
A new Science Translational Medicine study suggests obesity may leave a “molecular memory” in adipose-tissue macrophages.
Obesity alters RNA splicing, disrupting SR-BI, efferocytosis, and lipolysis. Some changes persisted in mice even after switching to a low-fat diet.
Correcting the abnormal splicing restored macrophage function and improved fat mobilization in mice. Human tissue showed related changes, but therapeutic findings remain experimental. Source:@ScienceTM
#Obesity #WeightLoss #Metabolism #MedicalResearch
🚨 Ebola Outbreak — DR Congo 🇨🇩
WHO Director-General Tedros Adhanom Ghebreyesus is calling for a major scale-up of the Ebola response in the Democratic Republic of the Congo.
The outbreak has reached 6 provinces and 60 health zones, with 6,186 cases and 3,007 deaths reported.
WHO estimates nearly $1.3 billion is needed to strengthen the response.
#Ebola #DRC #WHO #GlobalHealth #PublicHealth #Africa