Stephen Cochrane

Husband and father. Prof in Med Chem & Chem Bio. Avid runner and double world record holder. Personal Twitter. All views my own.

[Stephen Cochrane @Cochrane_lab]

#ChemistryOfRunning Mission Complete with a a 2.48 today @LondonMarathon Thanks to my my family for their continued love and support as I do mad stuff like this. I'll be writing a full race report for @ChemistryWorld in May 😁 Now, all the food and beer please

[Guinness World Records @GWR]

Science is our favourite subject 🧪
Stephen Cochrane broke the record for the fastest marathon dressed as a scientist (male)
@RoySocChem #LondonMarathon

[SutherlandGroup @AndySuthLab]

A 4 year post-doc position is available in the Sutherland group to work on novel fluorescent amino acids and peptides. Closing date for applications is 26th May. See here for more details and how to apply: https://t.co/cCbykwiKOZ

[Stephen Cochrane @Cochrane_lab]

New group photo 😀

[Stephen Cochrane @Cochrane_lab]

We summarise major methods to access lipid II, including direct bacterial extraction, (chemo)enzymatic approaches, and my personal favourite, total synthesis. If you want to know how to access lipid II, this is your source! @milandip @qubchem @BBSRC

https://t.co/RCTAROwRBz

[Stephen Cochrane @Cochrane_lab]

@hamamoto_h Sounds good! Yes we did also synthesize biotinylated menaquinone. Please send me an email s.cochrane(at)https://t.co/oTcObFfTRv and we can discuss further

[Stephen Cochrane @Cochrane_lab]

@_P_McD @Translink_NI Have you left Portadown yet?

[Stephen Cochrane @Cochrane_lab]

@hamamoto_h You are very welcome! You've done some beautiful work over the years on this fascinating class of antimicrobial peptides.

[Stephen Cochrane @Cochrane_lab]

Great to see our review on menaquinone-binding antimicrobial peptides (MBAMPs) now online 😀 If you're after a concise review / perspective covering synthesis, SAR and mechanism, look no further! @EilidhMatheson_ @ChemBioChem

https://t.co/OgWtwSU7G2

[QUB - Chemistry & Chemical Engineering @QUBCCE]

Very proud to announce that @DrKevinMorgan has been awarded an @AdvanceHE National Teaching Fellowship (NTF) in recognition for his outstanding impact on student outcomes and the teaching profession! More here: https://t.co/pMu0pVyQG0

[Markus Weingarth @MarkusWeingarth]

We are expanding our team at Utrecht University and we are looking for a Research Technician w/ interest in natural product isolation (especially lipids) for applications in drug development and pharmaceutical formulations.

Apply here:
https://t.co/ufw2QDFtv2

#jobs #technician

[Stephen Cochrane @Cochrane_lab]

Two referee reports back for a nice little review we submitted. One report 37 words, the other 1675 words!

[Stephen Cochrane @Cochrane_lab]

@AndySuthLab Thanks Andy!

[Stephen Cochrane @Cochrane_lab]

Our @ChemicalScience article on redox polyprenyl probes to study menaquinone-binding antibiotics is now properly online, along with our front cover artwork 😀

https://t.co/gfDMUq6oDx

[Stephen Cochrane @Cochrane_lab]

🧵1/ Our latest @ChemicalScience paper😀 Direct chemical labelling of polyprenyl quinones to study antibiotic–quinone interactions in real time on membranes ⚗️🔬 #ChemicalBiology #Antibiotics @ERC_Research @UKRI_News @QUBCCE

https://t.co/cTmrIhiiN0

[Andy Lawrence @biomimetic_chem]

A postdoctoral position, funded by the @LeverhulmeTrust for up to 36 months, is available to join my group @EdinburghChem. The project focuses on biomimetic approaches to natural product synthesis.

Deadline: 28th August 2025.

https://t.co/S5GelmP6Cv

[Stephen Cochrane @Cochrane_lab]

Have had a glorious two week family break in the Counties of Kerry and Cork. Highlight for me was trip to Ireland's most Southern habited island, Cape Clear. Honestly not sure two weeks is enough to properly recharge and considering taking four next summer! 🌞

[Stephen Cochrane @Cochrane_lab]

@RooneyChemistry Congrats Lorcan!

[Stephen Cochrane @Cochrane_lab]

@AndySuthLab @EilidhMatheson_ Thanks Andy!

[Stephen Cochrane @Cochrane_lab]

@MarkusWeingarth Thanks Markus! Looking forward to continuing to work with you on this.

[Stephen Cochrane @Cochrane_lab]

@researchitgg @NatMart_Chembio @UniLeidenNews ITC suggests that for Hex-LysE ∼0.2 : 1 MK: peptide, and ∼0.04 : 1 MK: peptide for Hex-MBA2. We were initially surprised by this but it made sense when we saw the aggregation in vesicles.

[Stephen Cochrane @Cochrane_lab]

🧵1/ Our latest @ChemicalScience paper😀 Direct chemical labelling of polyprenyl quinones to study antibiotic–quinone interactions in real time on membranes ⚗️🔬 #ChemicalBiology #Antibiotics @ERC_Research @UKRI_News @QUBCCE

https://t.co/cTmrIhiiN0

[Stephen Cochrane @Cochrane_lab]

7/👏 Hats off to @EilidhMatheson_ for spearheading this project and our collaborators @NatMart_Chembio and @MarkusWeingarth labs - a fantastic collaboration across chemistry & biology! 🌍🔬

[Stephen Cochrane @Cochrane_lab]

6/ Key impacts: 📸 Mechanistic insight into quinone-binding antibiotics 💊 Toolkit for new antibiotic development 🧫 Probes for live-cell membrane biochemistry 🧪 General method for tagging hydrophobic PPQs