Take a break from doomscrolling and read up on everything you ever wanted to know about Tackling Undruggable Targets with Designer Peptidomimetics and Synthetic Biologics. Fun writing this with @ColinSwenson, Guna and Debbie in my lab!
https://t.co/nJWJu3GyZY
Excited to share our work on synthetic,โartificialโ transcription factors. We present one solution to design non-natural, high affinity, specific and stable synthetic transcriptional repressors (STRs) that compete with MYC or other bHLH TFs for DNA binding https://t.co/ac55imej3B
Darts and snacks in the city with the lab. Lots to celebrate as we head into academic yr, not the least of which being recently granted F32 and T32 for @ColinSwenson and Olivia Laxton.
Bit delayed; 2020 was a rough year but we still managed to get out a paper, go check it out!
Laser-Induced Chemistry Observed during 248 nm Vacuum Ultraviolet Photolysis of an O3 and CH3NH2 Mixture https://t.co/hriwIioHjs
HUGE congratulations to our peptide nucleic acid exec extraordinaire, @ColinSwenson, on defending his PhD!!! Cheers to your bright future at @UChiChemistry and beyond xx ๐๐
Excited to finally share our latest work out in @J_A_C_S! We repurposed an endonuclease enzyme to bind and enrich A-to-I edited RNAs prior to sequencing and doubled our sensitivity. Looking forward to using EndoVIPER-seq to answer new questions! #WeDidIt https://t.co/UHDhn5Awp2
In this Feature Article, @jenheemstra & @ColinSwenson highlight the ability of peptide nucleic acids as peptide mimics, and their untapped potential to encode information in the amino acid sequence ๐
Interested? Read it here โก๏ธ https://t.co/jcLKdQi7gO
Sometimes we Heemstra Lab members produce beautiful colors for #FluorescenceFriday. Other times @ColinSwenson makes this terrifying blob. What do you think it is?
Parlez vous protein? @HeemstraLab teach molecules to speak both nucleic acid and protein languages simultaneously
@ColinSwenson@jenheemstra
https://t.co/QTO4RNJG8v
Congrats to @ColinSwenson@ChemHector@ArventhV for reporting in @J_A_C_S the first biopolymer that simultaneously speaks both amino acid and nucleotide languages! Even biomolecules can benefit from having a translator! https://t.co/Fst99OaJFD