People with persistent irreversible brain disorders come to us as a last resort. And we re-diagnose them. We turn their original diagnosis upside down and treat them. The brain disorder reverses. Patients get their lives back.
New episode #MustWatch
https://t.co/uCc4Ahf6tV
I just f**king love how the @BBCOne destroyed the "social drinking is pretty much ok" myth with this fantastic narrative which is only a bit over 60 seconds. We need more of this. Much more. Featuring marvellous Hepatologists from across the UK including Prof. @DebbieShawcros1
Remember. A woman can get severe liver disease with lower limits of alcohol use than men. It's not the liver disease I'm worried about, it's the terrifying breast cancer. And 20 other types of cancers including the most hellish of them all, pancreatic cancer (the pain cannot be described).
Alcohol is not beneficial in any dose, or form.
Prof. Debbie Shawcross mentioned liver failure in 20 year olds due to alcohol use. My youngest patient that fell victim to alcohol was only 19. He vomited nearly half his total blood volume...collapsed at home...hit his head on the floor...bled into his brain...went into a coma...died on the ventilator, all in 2 days time. Just 19 years old.
Read more on this here: #mustread
‘I had no idea being a social drinker would damage my liver by 31’ by @hazelreporting for @BBCPanorama
https://t.co/zlg9HoCOCq
@RamjiFire@MoHFW_INDIA We apologise for the delay in transit. It was delivered on 22nd as per our records. Please do contact our helpline if you need any further assistance. Thanks.
Competent Manpower shortage plague not only @CDSCO_INDIA_INF & SLA for Drugs but also internationally in EU & USA FDA .There is no need to have an army of inspectors for #MedicalDevices if task can bdelegated to 3rd Party CBs @mansukhmandviya
https://t.co/kwOKVv1lLO @jo_da123
Irrespective of your ideology, @theliverdoc should be supported in this issue. What he stood for is science and EBM, this will set a bad precedent. Tomorrow any company selling harmful drugs will start suing doctors for merely stating things that benefits community at large.
#india #medX #MedTwitter
Hey do you want to hear something really cool about the liver?
You know that we have a 'body clock,' right?
This internal biological clock is responsible for the 'circadian rythmn' that drives various body processes in a 24 hour period.
Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle.
One of the most important and well-known circadian rhythms is the sleep-wake cycle. Circadian rhythms are influenced by light and dark, as well as other factors.
But what controls these biological clocks?
A master clock - which resides in the brain.
In humans, the master clock is a group of about 20,000 nerve cells (neurons) that form a structure called the suprachiasmatic nucleus, or SCN. The SCN is in a part of the brain called the hypothalamus and receives direct input from the eyes.
But a group of researchers from the University of Queensland has found that it was not just the brain, but also the liver - that functions as the master clock!
To figure this out, they turned to our best lab buddies - mice.
Mice are nocturnal animals...meaning, they are very active at night and mostly finish off their napping sessions (a mouse sleeps for 12h a day) during the day and late evenings.
But these researchers did something strangely cool. They transplanted human liver cells into mice, to replace their mousy-liver cells.
And the mice started behaving weird.
They ate and slept at different times compared to mice without transplanted human cells. The mice started to eat and be active before night-time began, which was very unusual for a nocturnal animal.
Basically, their biological clock became more "human."
What does this mean?
The liver is a master organ.
It has more secrets in it, than we can ever imagine, but will unlock in due time.
And any disease affecting the liver, can disrupt your circadian rythmn/ biological clock...
...which is why in patients with cirrhosis - their sleep-wake cycle is disrupted - they tend to sleep more during day, and are more active at night (like an actual mouse) - a condition called minimal (covert) hepatic encephalopathy.
This is also the reason why patients with diabetes, when they have fatty livers, they have disrupted sleep - many people with type 2 diabetes experience poor sleep quality or insomnia.
If the liver is healthy, your normal functioning, especially sleep-wake cycles, become better.
So remember, keep yourselves healthy so that your liver, the master clock remains healthy.
Here are fews tips on keeping a healthy liver in case you missed it before. Here https://t.co/eqsUSQsHtR and here https://t.co/ESp5UY9DqY
Source:
Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior
https://t.co/rvjbC6cvUx
Many many Thanks 🙏🏻 to Dr @mansukhmandviya ji fr yr kind assurances to have the Bill of Drugs & Devices reviewed by an Appropriate Committee to ensure Modern Progressive laws so that @makeinindia of #medicaldevices is accelerated to achieve our Destiny of being a leading Mfg Hub