사실 고양이는 태어날 때부터 신장 청소 능력에 결함이 있다.
AIM이라는 단백질은 혈액 속을 돌아다니며 신장에 쌓인 세포 찌꺼기를 표시해두면,
면역세포가 와서 치워가는 구조다.
사람·개·쥐는 신장이 손상되면 AIM이 자동으로 출동해서 청소를 시작하지만,
고양이는 청소부가 출동을 못한다.
고양이의 AIM은 평소에 IgM이라는 단백질에 꽉 묶여 있다.
문제는 이 결합력이 다른 동물보다 1,000배 강하다는 것.
신장이 아무리 망가져도 AIM이 풀려나지 못한다.
이렇게 되면,
찌꺼기가 신장에 계속 쌓임 → 만성 염증 발생 → 신장 조직이 딱딱하게 굳음 (섬유화) → 기능하는 신장세포 감소
→ 만성 신부전 진행
이게 바로 15살 이상 고양이의 80%가 신장병에 걸리는 이유이다.
일본 도쿄대 미야자키 교수팀이 개발한
rAIM 주사제는
묶여있는 AIM 대신, 자유롭게 움직일 수 있는 재조합 AIM을 주사로 보충해주는 방식으로,
임상시험 결과는 다음과 같다.
치료 안 한 그룹: 1년 생존율 20%
rAIM 주사 그룹: 1년 생존율 80~83%
현재 2026년 일본 승인 신청 완료 되었고,
빠르면 2027년 봄 상용화 예정이다.
지금까지 고양이 신장병은 "진행을 늦추는 것"이 전부였는데, AIM은 진행 자체를 멈추는 최초의 치료제가 될 수 있다.
Good morning, XRPL fam! ☀️🚀
Today is THE day—Permissioned DEX (XLS-81) goes LIVE on the XRP Ledger in just over an hour! 🔥
https://t.co/fgX5kZO9hO
Permissioned Domains already activated (Feb 4), Token Escrow live, and now the native DEX gets credential-gated magic: Open, Permissioned & Hybrid offers unlocked.
This is the instant flip-of-the-switch moment we've waited for—compliant liquidity pools, RWA tokenization, RLUSD flows, and regulated trading environments go active RIGHT NOW for early adopters and builders. Deep, bad-actor-proof liquidity incoming.
Institutions? They might move more measured—waiting for full regulatory clarity (Clarity Act vibes) to fully deploy at scale and route massive cross-border volumes on-chain. But the infrastructure is HERE. No more excuses.
XRP as the neutral bridge asset just leveled up HARD. Real utility era accelerating. Trillions in TradFi liquidity eyeing the on-ramp.
Buckle up—this silent build turns LOUD soon.🪖💜
#XRP #XRPArmy
@HealthRanger They are a Ripple partner and have used the technology and knew about the technology since 2019, with that being said it is to create a level playing field among all countries this way u can't have sanctions on other countries it eliminates those all together
@RealAlexJones I used to see peter Nygard once a week at least driving one of his fancy Jaguars the company he owned was down the street from where i live, who tf would have ever thought a guy like that would be soo dark and fuckd up it just blows my mind
@Lafarge_Canada Net 30 days and still can't pay contractors on time! A fuckn multi billion dollar company who treats their employees and contractors like shit and can't pay them on time and its fuckn Christmas to boot! Lafarge=The Grinch!
https://t.co/5Ul5kEfTWw wtf is with not being able to log in on a new phone? Resent email at least 10 times now tried on the app and online cant access my account. It shouldn't be that hard to send a link to login again. And nowhere to contact anyone or get help with it 🤷♂️
@gregbradyx We drove from Winnipeg to toronto cause my wife can't fly to see an endocrinologist as my wife was treated here for regular tumors with zero results when she should have been referred to a specialist like an endocrinologist probably 10 years ago as she has endocrine tumors.
@deicivitas Ya it might be free here but its terrible especially when u do have serious health problems, about as useless as helathcare can be and the people in helathcare are trying but zero support and shortages everywhere its disgusting