Dennis A DiMaggio Jr

Postdoctoral researcher in the #Brinsmadelab Studying Staphylococcal physiology at Georgetown University 🦠🧬🧫🧪🔬

[Dennis A DiMaggio Jr @DADiMaggioJr]

Quick weekend read! I’m excited to announce that the preprint for a major chapter of my thesis work is out on BioRxiv! In this study, we highlight the essential role that pyrimidine metabolism plays in promoting activity of the SaeRS TCS in Staphylococcus aureus! 1/3

[bioRxiv Microbiology @biorxiv_micrbio]

Pyrimidine sufficiency is required for Sae two-component system signaling in Staphylococcus aureus https://t.co/cheZljQTXw #biorxiv_micrbio

[Dennis A DiMaggio Jr @DADiMaggioJr]

#MRSA #brinsmadelab #pyrimidines #bacterialpathogenesis #virulence #regulation #pyrimidinesareimportanttoo #twocomponentsystems #membranebiosynthesis

[Dennis A DiMaggio Jr @DADiMaggioJr]

Quick weekend read! I’m excited to announce that the preprint for a major chapter of my thesis work is out on BioRxiv! In this study, we highlight the essential role that pyrimidine metabolism plays in promoting activity of the SaeRS TCS in Staphylococcus aureus! 1/3

[bioRxiv Microbiology @biorxiv_micrbio]

Pyrimidine sufficiency is required for Sae two-component system signaling in Staphylococcus aureus https://t.co/cheZljQTXw #biorxiv_micrbio

[Dennis A DiMaggio Jr @DADiMaggioJr]

Thank you to my colleague Won-Sik Yeo for collaborating with me on this project! Also thank you to @SBrinsmade for the amazing mentorship and support along the way! 2/3

[Dennis A DiMaggio Jr @DADiMaggioJr]

Great meeting with amazing people, beautiful views, and interesting science! If you can, check it out! Be sure to submit abstracts by April 1!

[Shaun Brinsmade shaunbrinsmade.bsky.social @SBrinsmade]

Excited to convene the 69th Wind River Conference!! Always awesome science and great people. Keynotes: @DNAtransport @motile_microbe @joeBondyDenomy and Dr. Katherine Lemon (not on X). Join us, and please RT!

[Dennis A DiMaggio Jr @DADiMaggioJr]

Happy Holidays from the #Brinsmadelab at #GeorgetownUniversity! Decided to make some DIY lab reindeer out of some extra tubes and tips! #GUBiology #eppendorf #VWR #USAScientific

[Dennis A DiMaggio Jr @DADiMaggioJr]

Glad I had the opportunity to see the Aurora as far south as Virginia last night! Beautiful sight and amazing experience!

[Dennis A DiMaggio Jr @DADiMaggioJr]

Huge congrats to @alqahtanisaq on her publication! Glad I had the opportunity to contribute to her story! Check it out if you can! #brinsmadelab #gubiology #staphscientist @SBrinsmade

[Dennis A DiMaggio Jr @DADiMaggioJr]

PS. Overloading Thai food with chili oil is not a fun idea 😮‍💨🥴 @MohiniB1 @BradySpencer12

[Dennis A DiMaggio Jr @DADiMaggioJr]

Had an amazing time at the 68th @WindRiverConf in Breckinridge, CO! As always, great science and great company! Shoutout to everyone that presented and an extra shoutout the #brinsmadelab representation!

[Dennis A DiMaggio Jr @DADiMaggioJr]

Great news to end the week! Glad to see the collaboration with @karine_dufresne @carlamaduta and @superantigens lab is out in JBC!!! All thanks to a blurry picture of a nametag at the #staphylococcaldiseasesGRC @SBrinsmade

[Karine Dufresne @karine_dufresne]

Glad to see this one out in JBC! Thanks to @SBrinsmade and @DADiMaggioJr for their help deciphering the mechanism of action of our antivirulent, @carlamaduta for the Lactobacillus work and @Superantigens for encouraging my crazy ideas. Check it out: https://t.co/FmZpPt651w

[Shaun Brinsmade shaunbrinsmade.bsky.social @SBrinsmade]

Georgetown Biology representing at the ASM DC branch meeting! Zarrella and Brinsmade labs, and GU Biology alum Dr Zac Park! Great day of science and hanging out with friends and colleagues! @zanyzarr @ZachoryP @MarcellePhdBio @DADiMaggioJr @ASM_DCBranch @ASMicrobiology

[Dennis A DiMaggio Jr @DADiMaggioJr]

Check out the preprint from the wonderful collaboration with @karine_dufresne and @Superantigens lab! We show that a small bioactive molecule inhibits TSST-1 production to prevent mTSS and further show the impact of the compound on SaeRS! Solid 2024 so far in the @SBrinsmade lab!

[Karine Dufresne @karine_dufresne]

Here’s our new preprint: we screened a library of small bioactive molecules for inhibition of TSST-1 to prevent mTSS. Great collaboration with @SBrinsmade lab to demonstrate the impact of the compound on SaeRS. Great start of 2024 in @Superantigens lab!

[Dennis A DiMaggio Jr @DADiMaggioJr]

@karine_dufresne Congratulations Karine!!!!!!

[Dennis A DiMaggio Jr @DADiMaggioJr]

@SBrinsmade Enjoy your weekend, celebrate the fact that you made it through the submission, grant review, and all that life has thrown at you. Just know that we (the lab) are proud of all your hard work! #brinsmadelab #GoodVibesOnly

[Dennis A DiMaggio Jr @DADiMaggioJr]

@AugustusPendle1 Seeing code on the screen reminded me of this 😂
https://t.co/XY799BMhxG

[Biology @ Georgetown @GUBiology]

Grad spotlight *Dennis A. DiMaggio Jr.*
Program/year: 5th year Biology PhD student

Former program: Received my BS in Biology from Old Dominion University @BIOLOGYatODU

[Dennis A DiMaggio Jr @DADiMaggioJr]

@GUBiology @BIOLOGYatODU Shoutout to the #brinsmadelab @SBrinsmade

[Dennis A DiMaggio Jr @DADiMaggioJr]

@zanyzarr @Georgetown Congratulations!!! Looking forward to having you around!

[Dennis A DiMaggio Jr @DADiMaggioJr]

#brinsmadelab #staph #GRC #phdstudent #theband

[Dennis A DiMaggio Jr @DADiMaggioJr]

Greatful for the opportunity to present and attend the #StaphylococcalDiseasesGRC It was an awesome experience! Great science, even better people, and tons of memories! What more could you ask for! @GUBiology @SBrinsmade