Trader Lab

Medicinal Chemistry and Chemical Biology Lab @ UC Irvine

[Trader Lab @DJTraderLab]

The immunoproteasome as prodrug target to release MMAE in vivo? Check! Excited to continue to pursue this new drug discovery avenue. Congrats to first author Cody Loy and thank you to our amazing collaborators Claudia Benavente and Lisa Wagar!

https://t.co/398ultRP6T

[Trader Lab @DJTraderLab]

Excited to share more about the ByeTAC story! New paper in JACS describing the ability of a ByeTAC to degrade CRBN and Rpn13.

Congrats to Cody Loy and Shawn Vinogradsky!

https://t.co/V7QzYpjGZv

[Trader Lab @DJTraderLab]

Please join us to learn more about applying for a PhD in PharmSci at UCI!
https://t.co/AuGvVIcz7Y

[Trader Lab @DJTraderLab]

New degrader paper using the immunoproteasome and degrons! Congrats Cody Loy and Timothy Harris!

https://t.co/rfGWEm9MwX

[Keriann Backus @Keribackus]

Thrilled to share our new study in @nchembio describing the proteome-wide impacts of electrophile stress in the context of covalent fragments. Big congratulations to first authors Ashley Julio @AshleyJulio4 and Flowreen Shikwana @FShikwana ! 1/5 https://t.co/4bBtk5jI3J

[Nature Chemical Biology @nchembio]

A new paper from @TheAlbrecht_Lab and @LJSeabrook developed a targeted protein degradation platform, MrTAC, that enables arginine methylation-driven degradation of intracellular proteins in lysosomes https://t.co/p8tGSsY0Ip

[Laurence Seabrook @LJSeabrook]

I’m so excited to welcome MrTAC to the world of targeted protein degradation! We created a chemical inducer of arginine methylation that can be used to degrade proteins in lysosomes 💊 So grateful for everyone involved in this project 🥳🥳 https://t.co/k3ltO0LKfB

[Trader Lab @DJTraderLab]

Congrats Cody and Saayak on your immunoproteasome probe paper!

https://t.co/awN9znoNWr

[Trader Lab @DJTraderLab]

Excited to see this happening. Go proteasome stimulation!!! https://t.co/rZhrbvN20d

[UCI School of Pharmacy & Pharmaceutical Sciences @UCI_SPPS]

UC Irvine’s Pharmacological Sciences PhD Program is hosting a VIRTUAL Info Session on Wed, Sept 11 from 12 pm – 1 pm PST. Join us to learn about the Pharmacological Sciences PhD Program, the Admission process, and helpful campus resources. Register: https://t.co/8tu1l6tC2w

[Trader Lab @DJTraderLab]

Congrats @CodyLoy45 on your RSC ChemBio paper on a caged luciferin probe for the immunoproteasome!
https://t.co/sTuBaD3xvZ

[Trader Lab @DJTraderLab]

Congrats @CodyLoy45 on your recent review on the proteasome's primed substrate channel!
https://t.co/lhzLzhzQPu

[Trader Lab @DJTraderLab]

@Keribackus Congrats Keri!!!!!

[Trader Lab @DJTraderLab]

@CodyLoy45 So proud of you!

[Cody Loy @CodyLoy45]

Had an amazing experience at my first Bioorganic Chemistry GRC! From the exciting talks to making some incredible friendships, I can’t wait to go back to science summer camp. 🧪🏕️ Oh, and winning an outstanding poster award wasn’t too bad either!

[Trader Lab @DJTraderLab]

@DamianYoung29 Thanks Awesome Damian! Congrats!

[Trader Lab @DJTraderLab]

Huge congrats to these FIVE amazing PhD candidates in the lab! Cody Loy, Kate Kragness, Tim Harris, Duno Dantis, and Jaida Osman

[Dr. Donna Huryn @DMHuryn]

We have an opening for a #chempostdoc in the @DMHuryn lab to work on our med chem / chemical biology kidney disease project. For more info - and contact info: https://t.co/F5kgEikRM0

[UCI School of Pharmacy & Pharmaceutical Sciences @UCI_SPPS]

Discover the secrets to PhD success! 🥼🔬

Listen to @TheAlbrecht_Lab on her tips to becoming a successful PhD student at @UCI_SPPS.

#UCISPPS #UCIPharmSci #FuturePhD #PhDStudent #GradSchool

[Trader Lab @DJTraderLab]

Congrats Candidate Cody!