Danielle Johnson

Trial statistician at LCTC
Pharmacogenetic clinical trials PhD at University of Liverpool
#personalisedmedicine
she/her/they/them

[The PhD Place @ThePhDPlace]

You will finish your PhD

[Ellen Davenport-Pleasance @EllenPleasance]

I don't normally write this sort of tweet but I am at the end of my tether. My PhD is funded by @ubeldtp part of the @ESRC and I have not received a stipend payment for 47 days. I simply do not know how I am expected to live on pay I received in August

[Greenpeace UK @GreenpeaceUK]

Amount of land in the UK taken up by:

Golf courses = 1,256 km2
Solar farms = 230 km2

If government ministers want to put our land to better use, why don't they take a look at golf courses first?

[Marion Campbell @MarionKCampbell]

I included a #PatientPreference trial in a talk at last week’s #ICTMC2022 which generated quite a bit of discussion. Thought I’d follow up with a few notes on the design. 1/8
#MethodologyMonday

[Kit Yates @Kit_Yates_Maths]

Despite their claims of being "guided by the science", the UK government's response to the pandemic frequently ignored scientific advice.

Now that the UK's pandemic inquiry has opened scientists are increasingly being blamed for government mistakes.

A 🧵

1/25

[Marion Campbell @MarionKCampbell]

Common query came up again this week - when it is okay to exclude patients from a trial following randomisation. In theory, and especially under the intention to treat principle, once randomised, you are “in” the trial and it should remain that way. 1/5
#MethodologyMonday

[Danielle Johnson @DJohnsonTrials]

@Kit_Yates_Maths Definitely. I had the flu a few years ago and it was awful - since then always get a flu jab. Covid was awful too!

[Danielle Johnson @DJohnsonTrials]

@pijrrh @H0NEYRIVER interacting to be notified of the answer later...!

[Marion Campbell @MarionKCampbell]

One of my bugbears came up this week - the so-called “negative” trial. Trials where the overall p-value is >0.05 are not negative trials. There is no such thing as a negative trial - every trial (incl those with p>0.05) adds positively to the evidence base. 1/5
#MethodologyMonday

[Danielle Johnson @DJohnsonTrials]

@livia_scott_ Same! It took me an embarrassingly long time to realise what the hell they meant

[National Human Genome Research Institute @genome_gov]

Fren, I am hearing much about the Human Genome Project, but I am wondering if you are familiar with the Dog Genome Project at @genome_gov? A dog’s genetic blueprint is so similar to humans that researchers can compare them and gain new insights about dog and human health!

[Dr Meming @Dr_Meming]

The more I think about it the more The Lord of the Rings really resembles a PhD journey

[Danielle Johnson @DJohnsonTrials]

A viva, a niece, and a positive covid test all in the same fortnight 😅

[Danielle Johnson @DJohnsonTrials]

@LifeAfterMyPhD @mtqoi @hisotalus Agree, it was really bizarre. I think they're really predatory, they make it seem like nobody could ever get a job without their paid content!

[Danielle Johnson @DJohnsonTrials]

passed with minor corrections!! :D :D

[Danielle Johnson @DJohnsonTrials]

It's viva day!

[Danielle Johnson @DJohnsonTrials]

@crow_artist That settles it, I'm gonna get on your patreon :)

[Kit Yates @Kit_Yates_Maths]

I've updated the chart which shows the probability of sharing a space with someone with covid for the most recent ONS infection survey prevalence estimates for the UK (4.13%).

Worth bearing in mind when considering whether to meet indoors.

[Danielle Johnson @DJohnsonTrials]

@johnmoe No no, we've been trying to get him out for months now! It has been a slog