DNA-binding drugs📚

PubMed bot reporting DNA-drug and DNA-ligand binding. Maintained by @TeifLab. Also see @TF_binding_bot, @Nucleosome_Bot, @CTCF_Papers, @generegulation

[DNA-binding drugs📚 @DNAbinding]

Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein-Ligand Interactions and High Selectivity https://t.co/nuihHLkISV

[DNA-binding drugs📚 @DNAbinding]

SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation https://t.co/zZyiTLfzT2

[DNA-binding drugs📚 @DNAbinding]

A new small molecule DoNA binding to CAG repeat RNA https://t.co/JoynsJVMYx

[DNA-binding drugs📚 @DNAbinding]

Unleashing the binding interaction of chrysin-Cu(II) complex with the biomacromolecular targets: further studies of cell cytotoxicity and radical scavenging properties https://t.co/13nvtpVHgg

[DNA-binding drugs📚 @DNAbinding]

Pharmaceutical manifestation of Knoevenagel condensed metal (II) complexes through virtual, in vitro and in vivo assessments https://t.co/RPdIg2URk7

[DNA-binding drugs📚 @DNAbinding]

Structures of kinetic intermediate states of HIV-1 reverse transcriptase DNA synthesis https://t.co/WkNAJU44VA

[DNA-binding drugs📚 @DNAbinding]

Intrauterine arsenic exposure induces glucose metabolism disorders in adult offspring by targeting TET2-mediated DNA hydroxymethylation reprogramming of HNF4α in developing livers, an effect alleviated by ascorbic acid https://t.co/YUARPmP4cy

[DNA-binding drugs📚 @DNAbinding]

Applications of cryo-EM in drug development for STING https://t.co/RewHVlpnzM

[DNA-binding drugs📚 @DNAbinding]

Chemotherapeutic Mechanism of Action of the Synthetic Resorcinolic Methyl 3,5-dimethoxy-2-octanoylbenzoate https://t.co/RU4fK2ZhQo

[DNA-binding drugs📚 @DNAbinding]

Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial https://t.co/uBJEz4olfA

[DNA-binding drugs📚 @DNAbinding]

Signal-off nanozyme-based colorimetric aptasensor for sensitive detection of ampicillin using MnO2 nanoflowers and gold nanoparticles https://t.co/xFsxTYlFJf

[DNA-binding drugs📚 @DNAbinding]

Label-Free and Real-Time Optical Detection of Affinity Binding of the Antibody on Adherent Live Cells https://t.co/JhPUVjAMnj

[DNA-binding drugs📚 @DNAbinding]

Exploring the potential molecular mechanism of Gualou Guizhi decoction in the treatment of rheumatoid arthritis based on network pharmacology and molecular docking https://t.co/1WB7WqHSSS

[DNA-binding drugs📚 @DNAbinding]

Consistency of drug-resistant mutations in plasma and peripheral blood mononuclear cells of patients with treatment-naïve and treatment-experienced HIV-1 infection https://t.co/qMPYuOMRlO

[DNA-binding drugs📚 @DNAbinding]

Synthesis and antitumor activity of cyclopentane-fused anthraquinone derivatives https://t.co/ZqiXbnxIAd

[DNA-binding drugs📚 @DNAbinding]

Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sexual dimorphism in late-onset Alzheimer's disease https://t.co/wpnVdXPJgL

[DNA-binding drugs📚 @DNAbinding]

Mechanisms of Endocrine Resistance in Hormone Receptor-Positive Breast Cancer https://t.co/G6h37YPms1

[DNA-binding drugs📚 @DNAbinding]

Computational exploration of allosteric inhibitors targeting CDK4/CDK6 proteins: a promising approach for multi-target drug development https://t.co/6yDbPF39Vc

[DNA-binding drugs📚 @DNAbinding]

Recognition of human telomeric G-quadruplex DNA by 1,5-disubstituted diethyl-amido anthraquinone derivative in different ion environments causing thermal stabilization and apoptosis https://t.co/DmnqWX6ifY

[DNA-binding drugs📚 @DNAbinding]

Protein-DNA binding sites prediction based on pre-trained protein language model and contrastive learning https://t.co/KWylgkKsiz