๐งฌ๐ฏ LYMPHOMA GENOMICS MATCHING GAME
Welcome to todayโs episode of:
โMutation Meets Its Lymphoma Soulmateโ ๐๐ฌ
Rules are simple:
LEFT side = mutation
RIGHT side = lymphoma/entity
Your mission:
Match 1โ10 with AโJ.
No consults.
No molecular tumor board.
No hiding behind โclinical correlation recommended.โ ๐
Think:
๐ง MYD88 likes immune-privileged neighborhoods
๐งฉ EZH2/KMT2D whisper germinal center biology
๐ฃ CCND1 is wearing a mantle
๐ฅ BRAF V600E has a very hairy clue
Drop your answer key below:
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10-
Answer slide coming in 15 minutes.
Letโs see who can escape the lymphoma genomics maze. ๐งฌ๐ง
#Lymphoma #MedEd
Review series on CML: from diagnosis to treatment-free remission, prognostic factors continue to shape clinical decision-making in CML. A new review explores how risk assessment of CML is evolving.
https://t.co/kFvqBfiIjl
๐ง ๐๐ผ๐ปโ๐ ๐บ๐ถ๐๐ ๐๐ต๐ฒ ๐น๐ฎ๐๐ฒ๐๐ ๐ณ๐ฟ๐ผ๐บ ๐๐๐๐
Catch up on all IACH podcasts from ๐๐๐ป๐ฒ - expert discussions you donโt want to miss.
๐ Listen here:
https://t.co/QWzDM6sbvD
@Mohty_EBMT
A clinical diagnostic algorithm for evaluating anemic patients to distinguish between Iron Deficiency Anemia (IDA) and other forms of anemia, such as Anemia of Chronic Disease (ACD).
@MatthewHoMD
Rituximab and methotrexateโbased chemotherapy was associated with highest response rates and prolonged progression-free survival in ID-PCNSL. Read in Blood: https://t.co/R4ykK47pbf
Anti-dsDNA positive โ active lupus.
Before escalating treatment, ask:
๐น Symptoms?
๐น Complements falling?
๐น Proteinuria?
๐น Active urine sediment?
๐น Creatinine rising?
The antibody is a clueโnot the diagnosis.
๐ Treat the patient, not the antibody.
๐ Biopsy guides therapy, not anti-dsDNA alone.
๐ Trends matter more than isolated values.
#Rheumatology #Lupus #SLE #LupusNephritis #MedEd @docakx@IhabFathiSulima
Welcome to this week's EHA #LearningMondays challenge!
โ๏ธSubmit your answer (anonymously) in the form and unlock the detailed explanation: https://t.co/2zqtrS4fjO
๐ Thank you for your submission Dr Saskia Schols, Radboud University Medical Center, the Netherlands
๐กIndolent Mantle Cell lymphoma usually presents w/ leukemic non-nodal CLL-like w/ splenomegaly,
GI or blood/ bone marrow involvement only w/
Low tumor burden (Ki-67 proliferation fraction <10%)
SOX11 negative (IGHV mutated) is the most common biomarker for indolent disease.