S@m

Gearhead.

[S@m @Davy2Bones]

@Dig_raw21 Seems like people are lying for Social validation. Alright, time to drop social media now.

[Anshul Saxena @AskAnshul]

They are calling Ayush Malik an icon and hero because he left his family and converted his religion.

Our fearless hero and icon is KK Muhammad, who served as a Regional Director of ASI. His own community boycotted him and threatened him, yet he stood firm in stating that Temple ruins existed beneath the Babri Masjid.

We are not the same.

[Saloni @salonium]

New post!

@NikoMcCarty and I have been writing regular round ups for a little while now, but so much has happened recently that this month’s What's New in Biology post feels like it contains a year’s worth of breakthroughs.

https://t.co/uwC9WJDcxU

The most effective weight-loss drug so far, cancer breakthroughs, gene editing for cholesterol, ancestral CRISPR systems, a cure for some with hepatitis B, the first PROTAC drug, and more.

Read it here!

[Saloni @salonium]

All of these were reported over the past month:

• A new pancreatic cancer drug, daraxonrasib, that roughly doubles survival in late-stage disease
• A precision lung cancer drug, lorlatinib, that kept 55 percent of patients progression-free after 7 years, versus 3 percent on the old drug
• A prostate cancer drug, talazoparib, that halves the risk of progression
• An endometrial cancer drug, dostarlimab, where 58 percent of patients hadn't progressed after 4 years, versus 16 percent on chemo alone
• An early-detection blood test, the NHS Galleri test, that quadrupled cancer detection but missed its main goal
• An mRNA cancer vaccine that halved the risk of melanoma recurrence when added to Keytruda
• The most effective weight loss drug so far, retatrutide, which cut body weight by about 28 percent
• The first in vivo gene editing therapy, which cut hereditary angioedema attacks by 87 percent from a single injection
• A one-time gene edit, VERVE-102, that lowered LDL cholesterol by 62 percent
• A feat of pharmaceutical synthesis that raised enlicitide's manufacturing yield 14-fold using engineered enzymes
• A functional cure for hepatitis B, bepirovirsen, that cleared the virus in about 20 percent of patients
• The discovery that human cells can swap chromosome-sized DNA through nanotubes
• An ancestor of CRISPR, VIPR, found in bacteriophages, that silences genes without cutting DNA
• A preventive Covid-19 pill, ensitrelvir, that cut symptom risk by 67 percent after exposure
• The first PROTAC drug, vepdegestrant, which destroys a disease-causing protein rather than blocking it

Every month, Niko and I write a round up digging into the latest news in biotech and medicine, and this month's was astonishing.

We share some thoughts on what's responsible for this progress and what it means for science in the future.

[S@m @Davy2Bones]

@salonium Glad I found this account. Now I can read research on Social media as well.

[Lt Gen H S Panag(R) @rwac48]

Spot on!
India's nuclear doctrine faces a 2026 deterrence challenge https://t.co/MYlGqFrF2P

[कुशल मेहरा @kushal_mehra]

Read this to realise the level of corruption and incompetence

[Eminent Intellectual @total_woke_]

Show me an anti Hindu who is not anti India and show me one anti Indian who is not anti Hindu. India is Hindu. Period.

[Eason Tenzin🇭🇰🇹🇼 @IntelShadowOp]

这是孟加拉国的茶，里面加了昆虫这种特殊成分。因为中国人喜欢吃任何有生命的东西，所以这种茶在中国非常有名。这看起来难道不卫生吗？

[S@m @Davy2Bones]

@vinit_shenoy @NonsensicalNemo Abhikesh Balderjeet

[Anand Ranganathan @ARanganathan72]

All anti-Hindu acts brought in by Congress are still in force. The future of Hindustan is linked to the future of Hindus, and it is bleak if @narendramodi does not pay heed to Swami Vivekananda's warning: Every Hindu who converts is not only one Hindu less, it is one enemy more.

[S@m @Davy2Bones]

@TristinHopper Si, phaphda & jalebi are Gujarati cuisines.

[S@m @Davy2Bones]

@KreatelyMedia I don't know them & they don't know me.

[Nayanika @nayanikaaa]

On my first day in the DH Dissection Hall, I was uncomfortable about the cadavers not wearing underwear.

[S@m @Davy2Bones]

@nayanikaaa I did not know you were a Doctor. Sorry for my past reply whete I sent you the cadaver oath

[RushLane @rushlane]

Maserati appoints Navnit Motors as its official partner for Western & Central India

[S@m @Davy2Bones]

@NonsensicalNemo We musy club together, Erect a stage, Prick every offender & Penalise them for this behaviour, every on must Knob of these crimes.

[Nirmalya Dutta @NonsensicalNemo]

Blame comedian, spare laughing room?

I think anyone who was in the room ought to have an FIR filed agianst them. Everyone who was in the vicinity of the room should have an FIR. Everyone who has eyes should have FIR. Everyone who watched India Today should also get an FIR filed against them. FIR for everyone.

I think I need to let my rage die down before I write about this.

[Aravind @aravind]

This is a big win for India in the last decade.

But even with all such positives, there's an attempt at psyops by foreign seeded narrative using local politicians & account farms that India's environment is at threat.

So it can be used to program the public to fight India's strategic Andaman Nicobar port and military base development.

Public should not fall for it. Remember they are the same forces and it is same playbook adopted in Kenya to evict Adani from doing a project and capture it later.

[S@m @Davy2Bones]

@sagorika_s Sorry

[S@m @Davy2Bones]

HMT Kolam

[Sagorika @sagorika_s]

HMT Devi.