DeRenzoLab

CAR T cells for patients with Solid Tumors
St. Jude Children's Research Hospital

[DeRenzoLab @DeRenzoLab]

https://t.co/gC5nEOBIc9

[DeRenzoLab @DeRenzoLab]

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[Nick Vitanza @VitanzaNick]

So much fun to be part of the #ISPNO2024 immunotherapy debates with Elias Sayour, Frank Lin, @DeRenzoLab, & Dean Lee. See me here splitting up my talk by shamelessly plugging our open post doc position in the #VitanzaLab @seattlechildren

[DeRenzoLab @DeRenzoLab]

@JournalofExper1 @Ha_Won_Lee Great work out of @StJudeResearch, #osteosarcoma, #drugscreen, #CARTcell

[Journal of Experimental & Clinical Cancer Research @JournalofExper1]

New study!🏹

A high-content screen of FDA approved drugs to enhance #CART cell function: ingenol-3-angelate improves B7-H3-CAR T cell activity by upregulating B7-H3 on the target cell surface via PKCα activation

For free⤵️
https://t.co/PnrKAXPLSu

#Tcell
#Osteosarcoma

[DeRenzoLab @DeRenzoLab]

https://t.co/gC5nEOBIc9

[DeRenzoLab @DeRenzoLab]

CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity https://t.co/ZNmmAP39QU

[DeRenzoLab @DeRenzoLab]

CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity https://t.co/ZNmmAP39QU

[DeRenzoLab @DeRenzoLab]

Sharing our method to washout DMSO prior to @intracranialCART infusion
https://t.co/vdhS7xH30C

[DeRenzoLab @DeRenzoLab]

Congratulations Dr. Beckett!!!!!!!!!! So well deserved.

[Alex Beckett, PhD @AlexBeckettPhD]

Thesis defense completed ✅

[DeRenzoLab @DeRenzoLab]

Engineered CD47 protects T cells for enhanced antitumor immunity https://t.co/fozKZBFiky

Exciting work out of the Mackall lab!

[St. Jude Research @StJudeResearch]

We’re excited to share St. Jude has been ranked again among the top 5 pediatric cancer hospitals in the US by @usnews. Learn more about this achievement. https://t.co/eY9IxKxFfj

[DeRenzoLab @DeRenzoLab]

Check out this very interesting work by @dalia_haydar,
@GiedreKrenciute and colleagues to examine CAR T cells against brain tumors in the context of a fully immunocompetent environment. https://t.co/diYGhmU8Bv

[DeRenzoLab @DeRenzoLab]

Excited to share this new work. Ha Won, Carla and team did an exceptional job to show these new findings.

[DeRenzoLab @DeRenzoLab]

A high-content screen identified ingenol-3-angelate as an enhancer of B7-H3-CAR T cell activity by increasing B7-H3 protein expression on the target cell surface via protein kinase C alpha activation https://t.co/cGvrmY7QBZ

[DeRenzoLab @DeRenzoLab]

@biorxivpreprint Excited to share this new work. Ha Won and team did an exceptional job to show these new findings.

[Stephen Gottschalk @Kyttaro_Therapy]

Excited to share Peter Chockley's work on Synapse-tuned CARs out in Nature Biotech today

@NatureBiotech
@Kyttaro_Therapy
@StJudeResearch

Synapse-tuned CARs enhance immune cell anti-tumor activity | Nature Biotechnology https://t.co/HhrAw2QoJ4

[Journal for ImmunoTherapy of Cancer @jitcancer]

New #JITC article: CD47 expression is critical for CAR T-cell survival in vivo https://t.co/ZZ8as34Uj7 @itsalexbeckett

[DeRenzoLab @DeRenzoLab]

Fascinating work on this important aspect of CAR T cell biology.

[Alex Beckett, PhD @AlexBeckettPhD]

🚨My very FIRST first-author publication 🎉 in @jitcancer demonstrating the importance of CD47 expression in the context of CAR T cells. @PeterChockley ⁦@GiedreKrenciute⁩ @ShondraP_Miller @Kyttaro_Therapy @StJudeResearch @stjudegraduate https://t.co/mzg002GRZw