Dechao Feng

Urologist#YMED-X executive#UCL H-Lecturer#Journal Editors#Aging #immune #biorhythm #big data

[Research @Research_Jrnl]

Photodynamic Strategies for Prevention of Titanium Osteoimplant Infections. Click the link below to read this free, open access article. https://t.co/ApPpOJN40l

[Interdisciplinary Medicine (IMED) @MedicineIn17771]

🔬 New Review Alert | Interdisciplinary Medicine (IMed, IF=13.6, Q1)
Title: Multi-omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities
Inflammatory bowel disease (IBD) is

[Dechao Feng @DechaoF]

Honored to share our latest review on Research.
https://t.co/z0l6U0G7l8

[Research @Research_Jrnl]

Peripheral Nerve–Cancer Interactions in the Tumor Microenvironment: A Three-Dimensional Framework Integrating Mechanisms, Modulators, and Therapeutic Strategies. Click the link below to read this free, open access article. https://t.co/1lvjzp2Lr0

[Research @Research_Jrnl]

Peripheral Nerve–Cancer Interactions in the Tumor Microenvironment: A Three-Dimensional Framework Integrating Mechanisms, Modulators, and Therapeutic Strategies. Click the link below to read this free, open access article. https://t.co/1lvjzp2Lr0

[Research @Research_Jrnl]

PGK1 Lactylation-Driven Self-Reinforcing Loop Orchestrates Glycolytic Reprogramming in FSP1+ Macrophages in Liver Fibrosis. Click the link below to read this free, open access article. https://t.co/Lpr4LZNMNc

[Chinese Chemical Letters @ChinChemLett]

Engineering selenium-embedded NIR ratiometric probes for rapid visualization of thiols via electron density regulation

https://t.co/aHgtvcKqjv

[The Innovation: a Cell Press partner journal @The_InnovationJ]

New in The Innovation Nutrition!
AI is driving a paradigm shift from passive to intelligent delivery in functional foods. Integrating multimodal targeting, sustainable biopolymers, and AI promises to overcome current bottlenecks, paving the way for precision nutrition.
https://t.co/oyIHxF7Z5v
#artificialintelligent #precisionnutrition

[Phenomics @Phenomics_J]

🌿❄️ New Research on #KandeliaObovata #ColdStress #MultiOmics 🌊🧬✨
Transcriptomic & metabolomic analysis reveals how two mangrove populations differ in their response to extreme cold waves! 🎯🌡️
Key Insights:
✅ Northern Z-J population shows superior freeze resistance vs. southern F-J population 🇨🇳
✅ #ColdWave simulation (-4°C) causes severe damage to F-J during rewarming, while Z-J remains resilient 💪🍃
✅ #RNAseq & #LCMS metabolomics identify key pathways: photosynthesis, MAPK signaling, phenylpropanoid & JA biosynthesis 📊🔬
✅ #JasmonicAcid pathway & cuticle layer thickening crucial for Z-J cold tolerance – MeJA treatment rescues F-J 🌸🛡️
✅ #ERF transcription factors (including #KoCBF3) & target genes (e.g., #KoWRKY40) activated specifically in Z-J 🧬
📚Published by: Jiaqi Zhang, Tianyi Fan, Xingxing Cai, Sheng Ouyang, Ji Yang, Zhiping Song, Wenju Zhang, Yuguo Wang, Yan Zhu, Peng Nan
📅 Published in: 2025
📄 Full Study: https://t.co/IBbZy3yqHO
#ClimateChange #MangroveConservation #PlantBiology #Transcriptomics #Metabolomics #AbioticStress #JApathway #FreezingTolerance 🚀

[Phenomics @Phenomics_J]

🦠🦴 New Research on #GutHomeostasis #Osteoporosis & #GutBoneAxis 🧬✨
A comprehensive review highlights the bidirectional interplay between gut microbiota and bone metabolism, opening new therapeutic avenues! 🎯🩺
Key Insights:
✅ #Osteoporosis affects >100M people globally; gut dysbiosis directly impacts bone remodeling ⚠️
✅ Gut microbiota influences bone via #ImmuneSystem (#Th17/#Treg balance, #RANKL/#OPG ratio) 🛡️
✅ Microbial metabolites like #SCFAs (butyrate, propionate) promote bone formation & inhibit osteoclasts 💪🦷
✅ Gut dysbiosis increases permeability ("leaky gut"), elevates #LPS, driving systemic inflammation & bone loss 🔓🔥
✅ #Probiotics (#Lactobacillus reuteri), #Prebiotics (inulin, FOS), & #FMT show promise for improving bone density 🧪🦠
📚Published by: Peng Qi, Xin Chen, Hao Liu, Jilong Ma, Zhonghua Qi, Xingwen Xie
📅 Published in: 2025
📄 Full Study: https://t.co/4oNPxYptif
#Microbiome #BoneHealth #Inflammation #Probiotics #FMT #SCFAs #Th17 #Treg #RANKL #Osteoimmunology #GutBrainAxis 🚀

[Phenomics @Phenomics_J]

🪰🧬 New Research on #GutAging #LipaseH #Drosophila & #Lifespan 🔬✨
A study reveals that deficiency of gut-enriched Lipase H (Liph) accelerates gut aging and reduces lifespan through chronic inflammation! 🎯🕰️
Key Insights:
✅ #Liph (and its fly ortholog #CG6295) downregulated in aging gut tissues 📉
✅ #RNAi knockdown of CG6295 reduces lifespan, impairs gut integrity & lipid storage, and causes enterocyte flattening ⚠️
✅ Knockdown activates chronic immune responses (#Toll/#Imd & #JAK/#STAT pathways) & increases pro-inflammatory #Upd3 🔥
✅ #RNAseq reveals downregulated genes enriched in lipid metabolism & immune pathways 📊
✅ Liph downregulation in rat intestinal epithelial cells induces cellular senescence, confirming cross-species conservation 🐀🧫
📚Published by: Ayesha Nisar, Sawar Khan, Yonghan He (Commentary on Sun et al. 2024)
📅 Published in: 2025
📄 Full Study: https://t.co/Poy4yTH6yJ
#Aging #Inflammaging #LipidMetabolism #IntestinalHealth #Immunity #LifespanExtension #Drosophila #Senescence #TherapeuticTargets 🚀

[Phenomics @Phenomics_J]

🥑🧫 New Research on #KetogenicDiet #GutMicrobiota #BacterialGrowthRates 🦠🔬✨
Using CoPTR analysis, scientists reveal how KD alters gut bacterial growth dynamics – beyond just relative abundances! 🎯📈
Key Insights:
✅ #KetogenicDiet (high-fat, low-carb) alters gut microbiota composition & bacterial growth rates 📊
✅ Novel #CoPTR method measures in vivo growth rates – #Akkermansia muciniphila shows highest growth & abundance on KD 🚀🦠
✅ Discrepancies between growth rates & relative abundances reveal delayed responses in slow-growing bacteria (e.g., #Faecalibaculum rodentium) ⏳
✅ In vitro cultures confirm nutrient preferences: A. muciniphila thrives on soy oil but cannot grow on glucose ❌🍬
✅ Sudden starch intake after KD rapidly reverses metabolic state (↑glucose, ↓BHB) & alters microbial growth dynamics ⚡
📚Published by: Mi Tang, Zhidong Zhang, Liyuan Lin, Junling Niu, Guangxun Meng, Wei Wang, Jiwen Wang, Yingyan Wang
📅 Published in: 2025
📄 Full Study: https://t.co/FkPlt5RCOd
#KD #Microbiome #PTR #CoPTR #Akkermansia #Epilepsy #Metagenomics #GutHealth #BacterialGrowth #PrecisionNutrition #StarchEffect 🚀

[Phenomics @Phenomics_J]

We are very pleased to share that @Phenomics_J  was awarded an increased #ImpactFactor of 6.2 (Q1 journal) in the 2024 Journal Citation Reports (#JCR) from Clarivate Today! Additionally, according to data released recently by #Scopus (Elsevier), Phenomics received a #CiteScore of 6.8.

[Current Urology @Current_Urology]

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[Current Urology @Current_Urology]

New case series on RENAL ANASTOMOSING HEMANGIOMA (#RAH):
✅ Benign, often misread as cancer → unnecessary surgery
✅ Classic MRI tip: rim of nodules → centripetal fill-in
✅ When in doubt, biopsy & spare the nephron!
Read the full report (open access) 👉 https://t.co/2fFeI8wx1v #Urology #Radiology #Pathology #MedTwitter

[Current Urology @Current_Urology]

🎉🎉 Hey everyone! The latest issue is out now! This issue focuses on Advances in Prostate Cancer Research Check out the new cover & explore the latest research:https://t.co/tQlPGwLOTV #Maleurology ##Urologic tumors#Malehealth #PCa#CurrentUrology#prostate

[Current Urology @Current_Urology]

🚀 NEW REVIEW ALERT 🚀
CAR-based cell therapy is no longer sci-fi—it’s becoming a clinical reality for kidney, bladder & prostate cancers.
Our just-published Current Urology paper dives into:
✅ 48 ongoing trials (CD70, PSMA, PSCA, HER2…)
✅ CAR-T vs CAR-NK vs CAR-M: who wins in solid tumors?
✅ How to bust the “Big 3” barriers: immunosuppressive TME, antigen heterogeneity & organ-specific hurdles.
From bench to bedside—what’s hot, what’s not, and what’s next.
Read the open-access review, share your thoughts & let’s cure more urologic cancers together!
#CARtherapy #UroOnc #Immunotherapy #PrecisionMedicine
🔗 https://t.co/e9h5NUaXrh

[Current Urology @Current_Urology]

🔍 Rare #Kidney tumor alert! Just read a game-changing case series on renal anastomosing hemangioma — a benign mimic of #RenalCellCarcinoma that’s often misdiagnosed & overtreated. Key takeaways 👇
📊 124 patients, 70% asymptomatic, 87% misdiagnosed on imaging
🎯 MRI tip: peripheral nodular enhancement → centripetal fill-in
🧪 Pre-op biopsy can spare unnecessary nephrectomy
📖 Open-access full text: https://t.co/2fFeI8wx1v
RT to save a kidney! #Urology #Pathology #MedTwitter #Fellowship

[Current Urology @Current_Urology]

🔬 Hot off the press! Our new review in @CurrentUrology breaks down how the androgen receptor & DNA damage response "talk" to each other in #ProstateCancer—and why the conversation matters for your next Rx. PARP + AR combos, HRD vs HR-proficient, resistance loops, biomarkers on the horizon. Read it, share it, cure it! 👉 https://t.co/qNamUa7G5Q #pcsm #PrecisionOnco #PARPi

[Current Urology @Current_Urology]

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[Current Urology @Current_Urology]

🎉🎉 Hi！The latest issue of Current Urology is now online,This issue focuses on Advances in Prostate Cancer Research Check out the new cover & explore the latest research:https://t.co/RWCFH1fgnM 📖Read, cite, and let us know your thoughts.💡 #Maleurology ##Urologic tumors#Malehealth #PCa#CurrentUrology#prostate