@Clavicular0 Well Mr Clavicular I want you to know that it’s completely ok to get rejected or ignored or whatever. It happens with everyone. At least you are not a fat scumbag not trying anything and just jerking off to pornstars and eating potato chips with Oreo milk shake🧐
Can renal fibrosis become biologically reversible through simultaneous modulation of the gut microbiome, fibrotic signaling pathways, and regenerative extracellular vesicle therapy?
#ckd#kidney
@arsennelle@MadridXtra@AranchaMOBILE He’s a free agent and we can literally get him for free so I don’t think that’s him. For free he’s a great deal though🙃
@yuki_nakao1@NDTsocial Hey @yuki_nakao1
I’m a medical student from KMC Manipal. I’m deeply interested in Nephrology field because of my father’s diagnosis of CKD 2 years back and I’m very much involved and I keep reading basically everything about CKD and other topics.
It’s good to see someone like u
Vivek Agarwal's dad was admitted to MAX Hospital. Seven members of his family were staying at the Hotel Flourish Stays, where the fire broke out.
Not a single one of them survived. I’m stunned 💔
Shame on our policy makers and government officials.
#fire#delhi
A lot of people preparing for NEET PG have issues remembering which disease is autosomal recessive, what is dominant.
While ofcourse - at the end of the day it is a little bit of rote memorisation - there is a certain logic to it.
Remember- enzymes- pretty much of all them in our body are more than what’s required.
So, even a 50% enzyme activity suffices for majority.
Hence, unless enzymes are fully zero - disease won’t manifest.
So, any enzyme deficiency- will be AR - both genes have to be mutated/absent.
PKU
Galactosemia
Glycogen storage disorders
Congenital adrenal hyperplasia
Alpha 1 anti trypsin
Wilson
Even 1/2 Hb causes mild anemia - so even That/Sickle cell are AR.
Contrast this with neuromuscular damage in general.
Anything that causes damage to nerves and Muscle- even 50% damage would result in disease.
If you look at AD diseases - most are have some issues either with nerves or muscles or cytoskeleton.
Huntington
Myotonic dystrophy
Achondroplasia
Marfan
Hypertrophic cardiomyopathy.
Most neurocutaneous syndromes. (tuberous sclerosis/neurofibromatosis)
Ofcourse this is not hard and fast.
But serves to improve your memory and understanding.
X linked is genuinely just rote memorization. Those genes just happened to be on X chromosome.
A lot of people preparing for NEET PG have issues remembering which disease is autosomal recessive, what is dominant.
While ofcourse - at the end of the day it is a little bit of rote memorisation - there is a certain logic to it.
Remember- enzymes- pretty much of all them in our body are more than what’s required.
So, even a 50% enzyme activity suffices for majority.
Hence, unless enzymes are fully zero - disease won’t manifest.
So, any enzyme deficiency- will be AR - both genes have to be mutated/absent.
PKU
Galactosemia
Glycogen storage disorders
Congenital adrenal hyperplasia
Alpha 1 anti trypsin
Wilson
Even 1/2 Hb causes mild anemia - so even That/Sickle cell are AR.
Contrast this with neuromuscular damage in general.
Anything that causes damage to nerves and Muscle- even 50% damage would result in disease.
If you look at AD diseases - most are have some issues either with nerves or muscles or cytoskeleton.
Huntington
Myotonic dystrophy
Achondroplasia
Marfan
Hypertrophic cardiomyopathy.
Most neurocutaneous syndromes. (tuberous sclerosis/neurofibromatosis)
Ofcourse this is not hard and fast.
But serves to improve your memory and understanding.
X linked is genuinely just rote memorization. Those genes just happened to be on X chromosome.