Joe Whittaker

Hockey player for @cambsouthhc. Also... a blogger and tweeter about #genomics and a marketer of #NGS at @nanopore. Ex @illumina . Views are my own.

[Joe Whittaker @DiagnosticsJoe]

@kirk3gaard @gbw42 @nanopore R2P2 😜 love it.

[Sebastian S. Cocioba🪄🌷 @ATinyGreenCell]

Mmmmm, fresh genome. This is a peek at the nanopore data ahead of Illumina run next week. Amazingly fast turnaround time of TWO DAYS. Thanks, @plasmidsaurus!!! Already designing knockout cassettes as we speak. Engineering microbes for nice smells at @SenseoryPlants.

[Sarah Marzi @sj_marzi]

Newest lab member 🤩

[Joe Whittaker @DiagnosticsJoe]

@benagen3571 Love whoever has made these graphics (Mk1B)

[Joe Whittaker @DiagnosticsJoe]

Using 'only' a MinION device with adaptive sampling to generate long reads. Pocket-sized cancer detection for you🔥🔥

[Oxford Nanopore @nanopore]

Hanlee Ji and team are unlocking the mutational landscape of cancer at single-cell resolution. From BCL2 fusions to KRAS mutations — read how they’re revealing more about tumour heterogeneity: https://t.co/9tKet2R6UG

[James Zou @james_y_zou]

Excited to share our new study of #genomics🧬, #EHR📈 + treatment outcomes of 78K patients across 20 #cancers!

We identified >700 mutations predicting which drugs💊 are effective for individual patients. Our #ML model predicts who respond well to immunotherapy #precisioncancer

[Joe Whittaker @DiagnosticsJoe]

Nice. I remember doing a BBSRC summer internship in the UK on wheat varieties and the affect of take-all on them....both by hand, visual scoring, and a few basic molecular techniques...! 🤣

How times have changed in Ag!

[Earlham Institute @EarlhamInst]

Scientists from the Earlham Institute will head to #PAG32 next month, presenting their work during the '#wheatgenomics to breeding' session on using #genomeassemblies and ultra-long #Nanopore reads to identify key variations in wheat.

https://t.co/wf4BxqC0jP

[Joe Whittaker @DiagnosticsJoe]

Nice

[good papers @paperperday]

Towards Next Generation Protein Sequencing

review on nanopore protein sequencing
https://t.co/awAzpOWcdJ

[Joe Whittaker @DiagnosticsJoe]

P24! One of my favourites. I wonder what the T2T genome of Santa looks like…

[IGA Technology @IGATechnology]

🎄 Christmas has arrived a little bit earlier than expected here!
Ready to roll out #T2T #genome #assembly of complex genomes by Christmas Eve. 🎅✨
@nanopore #LongReadSequencing

[Tip @Thidathipw]

Christmas gift 🎁 @nanopore #MinION #Mk1D ✨🫶🏻

[Erik Karlsson @E_A_Karlsson]

Tis the season for #holiday lights. #avianinfluenza sequencing up and running on our new #mk1d from ⁦@nanopore at ⁦@PasteurCambodia⁩ . #nanopore #oxfordnanopre #genomic #h5n1 #alliwantforchristmas #anywhereanything

[Joe Whittaker @DiagnosticsJoe]

Something big is coming. And it’s (actually) small…

[Andrew Beggs @adbeggs]

Excited to show our latest attempt at a clinically meaningful clinical cancer genome with rapid turn around (24 hours!) times using Oxford Nanopore sequencing technology for patients who need a rapid, whole genome assessment of their tumour and germline, offering them (1/n):

[Tip @Thidathipw]

First P2 in #Thailand @nanopore #Siriraj
✨ #Bangkok

[Oxford Nanopore @nanopore]

PromethION 2 Integrated (P2i) is moving to open early access.

With its onboard compute and integrated screen, the self-contained device is bringing high-quality, real-time sequencing to a wider range of labs.

Learn more: https://t.co/8rEKIWSuhV #WYMM

[Oxford Nanopore @nanopore]

Direct RNA sequencing update!

We are pleased to announce that RNA004 is moving into open Early Access.

RNA004 provides higher outputs and accuracy compared to the previous version RNA002.

Learn more: https://t.co/5duflxkl9P 1/9

[Alexander Wittenberg @AW_NGS]

Great accuracy using @nanopore DRS RNA004 on total RNA. ~96-98% identity using sup calling. Example of a ~10.8 Kb full length 🥬 transcript below. 💥

[Andrew Beggs @adbeggs]

Well here's the @nanopore update.. we have carried out a hereditary cancer panel screen:
* ~200 genes
* 15mbases panel
* Coverage between 50-70x on target; 5x off target
* 16hr run time LSK114 + R10.4.1

This is PMS2 exon 10&11 - a notoriously difficult place to sequence with SR

[Thomas Bradley @TBradley27]

I am happy to say that as a result of direct support from the Brenton group, we now have an Oxford @nanopore PromethION 24 housed within the genomics core at @CRUK_CI!

Looking forward to see what we can discover with this technology

[Joe Whittaker @DiagnosticsJoe]

Looks so good...

[Cristobal Onetto @CristobalOnetto]

Some serious psychedelic art going on here. Putting the sticker was definitely harder than doing a library 😝. @nanopore