In the failing heart, short chain fatty acids (SCFA) are more readily oxidized than ketones & represent an unexplored source of energy production. Read more: https://t.co/AZ0VyHyi8P #AHAJournals@DougLewandowski
Lewandowski's lab show that long-chain acyl coenzyme A is depleted in failing hearts. Restoring it via #ASCL1 activation and mechanical unloading attenuates cardiac remodeling and failure. @CircAHA. #NatMetabPicks
https://t.co/9QJW4pJDIa