Ms Carbone

Consultant Plastic Surgeon & Clinical Director H&N surgery @CHFTNHS
#healthreformer #skincancer #breastrecon ▪️ Views are not my employers.

[Ms Carbone @DrACarbone]

So #sunbeds are safe? 🤔This has to be the dumbest UK weekly awareness campaign yet.🤦🏽 #melanomaawareness #melanoma_kills https://t.co/nM6pbjunzw

[Nora @NoraTheBora]

Ann Widdecombe has possibly been murdered, and @SkyNews thinks it’s appropriate to have a man discussing whether she was a virgin.

Why would whether a woman had ever had penetrative sex be relevant to her possible murder?

He then went on to speculate, on mainstream media, that it was a robbery gone wrong rather than politically motivated. That may ultimately prove to be the case, but speculation about motive before the facts are established has no place in responsible news coverage.

The first instinct when discussing a woman who may have been murdered should never be to reduce her to her sexual history. Ann Widdecombe deserved better. Every woman deserves better.

[David Yelland @davidyelland]

Don’t know her, but she made me cry.

[Adam Cailler @acailler]

Has there ever been a question as wild as this during #PMQs?!

[Satchin Panda @SatchinPanda]

Almost every hormone got circadian rhythm. In this figure so many of them peak when we get into our deep sleep after midnight. This may explain why sleeping less or late can disrupt hormone rhythms.
Review by Karen Gamble and Martin Young at UAB.
https://t.co/FzmFYwEmYS

[Zaid K. Dahhaj @zaidkdahhaj]

Mainstream dermatology never tells you that circadian clocks even exist, let alone that they regulate cancer risk

The Nobel Prize actually proved this

(2017, Physiology or Medicine)

The prize went to Hall, Rosbash, and Young for uncovering the molecular circadian clock inside cells

In every cell within the human body

They identified clock genes (CLOCK, BMAL1, PER, CRY) that turn genes on and off in 24-hour cycles, control when enzymes are made, regulate mitochondrial function, DNA repair, cell division, and apoptosis

Do you know what this means?

Biology is time-dependent by design

Circadian biology is the foundation of all biological systems because it controls everything downstream. Health is first and foremost a game of timing

There are a number of reasons why these circadian clocks control and impact cancer risk

1. DNA repair pathways are circadian-controlled

2. Cell division is timed to avoid UV and oxidative damage, another reason why UV is a hormetic eustressor and not inherently damaging

3. Clock disruption increases mutation rates and fundamentally destroys all anti-cancer defenses which are also under circadian control

There’s a reason why shift workers have a dramatically higher risk of breast, prostate, and colorectal cancer. This also explains why they have altered tumor suppressor gene expression. Their p53 function is cooked

Does your dermatologist know any of what I just laid out to you?

You should start asking them some questions and find out yourself

I can guarantee the answer is no

[Siim Land @siimland]

Circadian clock dysfunction affects virtually all the hallmarks of aging:
- chronic inflammation
- mitochondrial dysfunction
- loss of autophagy
- gut dysbiosis
- cell senescence
- telomere shortening

Graph: PMID: 36583849

[Norman Brennan @NormanBrennan]

His name? Wayne Broadhurst 49yrs Stabbed to death whilst walking his dog; 22yr Afghan National who arrived by lorry arrested;

Her Name? Rhiannon Whyte 27yrs mother of 5yr son; Murdered; Stabbed 23 times by Asylum seeker from hotel she worked at to help others;

#LEST WE FORGET😞

[Vicky Richter🇩🇪🇺🇸🇧🇷🇬🇧 @VickyR1chter]

The Politicians Who Kneel for Optics but Stand for Nothing

The man who dropped to one knee for George Floyd — oceans away and cameras ready — can’t find his voice for Wayne Broadhurst, a British man murdered on his own soil. Sir Keir Starmer’s silence is deafening. The same man who wept for imported causes can’t muster a syllable for a tragedy in his own country.

And he’s not alone in this theatre of selective empathy. London’s ever-silent mayor, Sadiq Khan, has posted three times about a hurricane in Jamaica — a tragedy, yes, but not his jurisdiction — and not once about the brutal murder of a man in the city he governs.

This is what modern moral leadership looks like: performative concern for the exotic, polite indifference to the domestic. The further away the victim, the louder the outrage. The closer to home, the tighter the lips.

They’ll kneel for applause but never stand for accountability. They’ll hashtag global suffering but ignore the blood on British streets.

Shame on you, Keir. Shame on you, Sadiq. Britain deserves leaders who protect its people, not politicians auditioning for sainthood on social media.

[Cian McCarthy @arealmofwonder]

Rest in peace, Patricia Routledge 🙏🏻

In memory of her, I encourage everyone to read these words of hers from February last year.

Whether young or old, you're bound to get something out of it.

*****

"I’ll be turning 95 this coming Monday. In my younger years, I was often filled with worry — worry that I wasn’t quite good enough, that no one would cast me again, that I wouldn’t live up to my mother’s hopes. But these days begin in peace, and end in gratitude.

My life didn’t quite take shape until my forties. I had worked steadily — on provincial stages, in radio plays, in West End productions — but I often felt adrift, as though I was searching for a home within myself that I hadn’t quite found.

At 50, I accepted a television role that many would later associate me with — Hyacinth Bucket, of Keeping Up Appearances. I thought it would be a small part in a little series. I never imagined that it would take me into people’s living rooms and hearts around the world. And truthfully, that role taught me to accept my own quirks. It healed something in me.

At 60, I began learning Italian — not for work, but so I could sing opera in its native language. I also learned how to live alone without feeling lonely. I read poetry aloud each evening, not to perfect my diction, but to quiet my soul.

At 70, I returned to the Shakespearean stage — something I once believed I had aged out of. But this time, I had nothing to prove. I stood on those boards with stillness, and audiences felt that. I was no longer performing. I was simply being.

At 80, I took up watercolour painting. I painted flowers from my garden, old hats from my youth, and faces I remembered from the London Underground. Each painting was a quiet memory made visible.

Now, at 95, I write letters by hand. I’m learning to bake rye bread. I still breathe deeply every morning. I still adore laughter — though I no longer try to make anyone laugh. I love the quiet more than ever.

I’m writing this to tell you something simple:

Growing older is not the closing act. It can be the most exquisite chapter — if you let yourself bloom again.

Let these years ahead be your TREASURE YEARS.

You don’t need to be famous. You don’t need to be flawless.

You only need to show up — fully — for the life that is still yours.

With love and gentleness,

Patricia Routledge

*****

Once more, rest in peace. 🤍

[Community Notes & Violations @CNviolations]

It just keeps getting better and better

[Bethany Dawson @bethanymrd]

bank holiday now but only for women

[Eye Clinic CHFT @ChftEye]

If you think you need may need A&E for a new onset eye complaint, don't forget you can be seen free of charge by your local Optician under the Primary Eye Care Acute Referral Scheme (PEARS)
👁
Please try keep our A&E free for serious and life-threatening conditions

#eyes

[Ms Carbone @DrACarbone]

#Missionimpossible 😍. Thank you Mr @TomCruise for your message at the beginning of the film. Must watch in the cinema. What a journey!

[Defiant L’s @DefiantLs]

This has me 💀

[Historic Vids @historyinmemes]

Scottish wildlife photographer Alan McFadyen set out to capture a kingfisher diving with no splash, no ripples and no drops. 6 years and 720,000 shots later, he finally got the shot

[Leddy @LeddyLLC]

Magnesium's the overlooked mineral Big Pharma didn’t want to talk about.

Meanwhile, millions kept battling:

- Constant fatigue
- Unexplainable anxiety
- Cravings that never stop

Here’s why it’s ESSENTIAL—and how to take it properly 🧵:

[BBC Nottingham @BBCNottingham]

Plastic surgeon guilty of trying to kill colleague - tap the pic to read more https://t.co/9RUfQhzHIL

[Tropical ‘wtf America’ 🇪🇺🇰🇾 🇬🇧 🇺🇦 @TropicalVertic1]

@P_Kallioniemi

[Donna Coghlan @donnac1188]

@RositaDaz48 I don’t know if this story is true, but to anyone who feels unimportant to another human being, please know you are important to God, and this life is short. You can spend eternity with the One Who loves you most.

[Global Index @TheGlobal_Index]

@nocapmedia This is how you make friends in Australia 🇦🇺