Cleveland Clinic Head and Neck Pathology

We evaluate more than 4,000 specimens each year, encompassing a wide spectrum of consultation cases (link for info - Managed by @HNPathology

[Mobeen Rahman @HNPathology]

Nasopharyngeal CA (Pics: HP, LP, p40, and EBV ISH). These can be very tricky as the tumor can be very subtle! Noteworthy feature in this case was the presence of concomitant granulomatous reaction (see PMID 1717637 and 32562216) #PathTwitter #pathology

[Scott Kilpatrick, MD @ScottBikeethan]

Even in a bone and soft tissue pathologist sometimes gets oral pathology cases when they involve bone. 30+ male with a posterior maxillary intra-osseous cystic mass. Thoughts? Important differential? Good confirmatory immunostains?
@smlungpathguy @HNPathology @ENT_Path

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

This last case was a tricky example of an oncocytic variant of salivary duct carcinoma (see HE with AR IHC in same area). Pos IHC: GATA3 and PanK; Some neg IHC: S100 and p63 @HNPathology @golgigriff

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

Parotid mass with multiple cervical lymph node mets. What is your DDX and what IHC would you order!
@HNPathology

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

Parotid mass with multiple cervical lymph node mets. What is your DDX and what IHC would you order!
@HNPathology

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

Thank you everyone for your thoughts! Excellent differential diagnoses were provided. The case is an example of an acantholytic SCC. P40+ IHC in the soft tissue deposit in the neck lymph node. @smlungpathguy @pathology @EntPathMan

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

@SalamAshourMD 👍

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

Polypoid vocal cord lesion. Look carefully in this exuberant epithelial proliferation! Diagnosis? #entpath #pathology

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

@Mark_PoolMD 👍

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

"Neck mass" dissected during glossectomy. What is your DDX of this neck mass? Will share diagnostic IHC and primary tumor pictures tomorrow morning 🙂 #pathology #entpathology

[Kathy Allen-Proctor @DrKathyAP]

Something pretty for y’all today: Calcifying epithelial odontogenic tumor (aka: pindborg tumor). The apple-green birefringent material is called odontogenic ameloblast-associated protein #SurgPath #ENTPath @ENT_Path

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

Examples of perineural invasion in different glossectomies.

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

NUT Midline CA (IHC: NUT antibody+)

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

One of our posters at #USCAP2020 - PAX8 has inconsistent expression in cribriform-morular variant of papillary thyroid carcinoma #pathology #entpath #medicine #thyroid

[Cleveland Clinic Head and Neck Pathology @ENT_Path]

Congratulations to our Head and Neck Pathology Fellow for being award the Leon Barnes Award at USCAP 2020! @DrKathyAP #USCAP2020 #pathology #medicine #Doctors

[Kathy Allen-Proctor @DrKathyAP]

Come visit this nerd and check out our poster about variability in DOI measurement in oral scc! #USCAP2020 #ENTpath @ENT_Path