Erica OllmannSaphire

President, CEO and very proud Professor @ljiresearch La Jolla Institute for Immunology. Women’s health and vaccine innovation. More coffee please.

[Erica OllmannSaphire @EOSaphire]

Congratulations to Dr. Sujan Shresta @ljiresearch on new funding from @NIAIDNews! Flaviviruses and alphaviruses are spreading — and this #vaccine research is critical

[La Jolla Institute @ljiresearch]

News: LJI Professor Sujan Shresta wins new funding to investigate #dengue and #chikungunya virus vaccines https://t.co/ObPv1wehs4

#Virology #Vaccines #InfectiousDisease #Health #Arboviruses

[Erica OllmannSaphire @EOSaphire]

It was an honor to be recognized w/the 2023 Pantheon Award - I’m grateful for the opportunity to contribute to the life sciences and inspire future innovators. As I pass the torch, I encourage you to nominate the next trailblazers here: https://t.co/eEaBExxfsm

#PantheonAwards

[Erica OllmannSaphire @EOSaphire]

Biomedical faculty search committees, what would you rather have, a candidate with a K99/R00 or a candidate with a career award from the Burroughs Wellcome Fund? A talented physician scientist here has won both, but must give one up. A good problem to have - but which to give up?

[Erica OllmannSaphire @EOSaphire]

LJI Asst Prof Sam Myers shows how to screen 1000s of post-trans mods to explore biochem pathways and circuits at scale - here, to explore T cell activation. Am beaming with pride at our new recruit and all he is building. @SAMyers_lab @ljiresearch

[Nature Methods @naturemethods]

New from @SAMyers_lab! Combining genome-wide CRISPR–Cas9-mediated base editors with temporally resolved phosphoproteomics enables the functional screening of thousands of post-translational modification sites involved in T cell activation.https://t.co/EtEoofQt8A

[Samuel A Myers @SAMyers_lab]

We preset an approach to test phosphorylation site function in high throughput. Like phenotypic CRISPR screens but instead of knocking out a gene, we mutate specific codons with base editors so the resultant protein cannot get phosphorylated that site.

[Erica OllmannSaphire @EOSaphire]

My kid just committed to a college in Boston. I’m now accepting any and all seminar trips to Boston for the next four years!

[Erica OllmannSaphire @EOSaphire]

Thank you Dr. Wezgryn ⁦@rwegrzyn⁩ for your comments at the Women’s Health Action Matters Forum. Yes, we can effect the needed changes for Women’s health in #3not30 years. The faculty of ⁦@ljiresearch⁩ and the nation are behind you, ⁦@ARPA_H⁩ and ⁦@WHAMnow⁩

[Miguel Reina-Campos @MReinaCampos]

Fun fact, this is me in Barcelona - summer of 2014 - showing off a freebie @Larallbb got me from her new job with the Schoenberger lab @ljiresearch

[Erica OllmannSaphire @EOSaphire]

A great collaboration with @UCSanDiego and @UCSDCancer

[La Jolla Institute @ljiresearch]

LJI Center for Cancer Immunotherapy and @UCSanDiego + @UCSDCancer scientists make an important advance toward personalized #immunotherapy for all types of #cancer.

Learn more about this #ImmuneSystem research: https://t.co/HGnmHYpHy2

[Erica OllmannSaphire @EOSaphire]

I'm thrilled to welcome Miguel Reina-Campos, Ph.D. (@MReinaCampos) to the @ljiresearch faculty! His #Tcell research has enormous potential for improving #cancer #immunotherapy and more https://t.co/HMSZwO4FhK

[Human Immunology News @humanimmunenews]

Under joint 🤝 leadership of Drs. Vijayanand & Ganesan, @ljiresearch researchers identified #neoantigens in pediatric #BrainTumors and showed that neoantigen-specific T cell gene signatures are linked to better survival outcomes.

🔗 https://t.co/8Nlj2BmIje

[Erica OllmannSaphire @EOSaphire]

@KizzyPhD @HarmitMalik I started a monthly flower delivery in the pandemic for morale. I still have it going.

[Erica OllmannSaphire @EOSaphire]

Absolutely beautiful #Ebola cryoET on infected and transfected cells with surprising insights. The most satisfying thing, after 20 years in this field, is how early biochemical puzzles are now fitting together @ReikaWatanabe2 @ljiresearch

[Reika Watanabe @ReikaWatanabe2]

We are excited to share our first in situ cryo-FIB-ET manuscript from @ljiresearch in biorxiv! We have revealed the nucleocapsid assembly process and presented the atomic model of the intracellular nucleocapsid of the Ebola virus, which causes highly lethal hemorrhagic fever.

[Erica OllmannSaphire @EOSaphire]

In-cell Ebola NC were in infected (deltaVP30 @HalfmannPeter) and transfected cells + other in-cell views of the Ebola nucleocapsid in the acts of assembly and condensation. Inspired and furthered by @williamnwan Tomo start on @USUKFulbright in @BriggsGroup Thank you ever so much.

[Erica OllmannSaphire @EOSaphire]

New on biorxiv, the Ebola virus nucleocapsid has an additional outer layer: NP+genome on the inside; alternating 1-up, 1-down VP24 in the mid; and a newly visualized outer layer of NP held RNA-free by VP35. CryoET @ReikaWatanabe2 #teamtomo @ljiresearch https://t.co/mwrioPJFYE

[Erica OllmannSaphire @EOSaphire]

LJI is truly a #compbio powerhouse. Learn how Assistant Professor Tal Einav uses immune cell data to predict how different groups (kids, seniors, men, women) may react to infectious diseases or new vaccines: https://t.co/U82ii4Ldb7 #DataScience #VaccineResearch

[Erica OllmannSaphire @EOSaphire]

Dr. Grifoni's lab is doing insightful work @ljiresearch

Her #Tcell research changes how we think about immune responses to #SARSCoV2 and other deadly viruses #SanDiego #Immunology

[La Jolla Institute @ljiresearch]

LJI Research Assistant Prof. Alba Grifoni (@Alba_Grifoni) investigates how we might harness #Tcells to better fight #SARSCoV2, #Lassa and more.

"You need to consider both T cell and B cell responses in vaccine design."

Read our Q&A with Dr. Grifoni: https://t.co/6KI5xHqAAy

[Erica OllmannSaphire @EOSaphire]

Very interesting work from @ljiresearch's Drs. Cheroutre, Kronenberg and Myers (@SAMyers_lab) on a process that turns T cells into fighters #InfectiousDisease #Immunology #Tcells

[Inside Precision Medicine @Inside_PM]

.@ljiresearch Research Reveals Unexpected Role of Nuclear Receptor in T Cell Activity Regulation

Scientists have uncovered a novel role for the nuclear receptor retinoic acid receptor alpha (RARα) in T cell activation. Learn more: https://t.co/xLYPu4cD24

[Erica OllmannSaphire @EOSaphire]

Congrats to @ljiresearch's new Chief Scientific Officer! I'm looking forward to partnering with Shane to build LJI's future #Immunology #Health

[La Jolla Institute @ljiresearch]

#Science News: La Jolla Institute for Immunology appoints Shane Crotty, PhD, as Chief Scientific Officer https://t.co/1jMl4snCU9

"Shane is an insightful and creative thinker, with an exceptional breadth and depth of knowledge." - @EOSaphire

#SanDiego #LaJolla #Health #Medicine

[Erica OllmannSaphire @EOSaphire]

Congratulations to Dr. Rinkesh Gupta, the first recipient of the new Michael Croft Fellowship in Immunology #Immunology #LaJolla #ImmuneSystem #Asthma #Ezcema #Allergy

[La Jolla Institute @ljiresearch]

News: LJI and @KyowaKirin_US launch #immunology fellowship program to support early career scientists https://t.co/79P7BLMHZN

#ImmuneSystem #Health #Medicine #SanDiego #Biomed