Egor Dolzhenko

Bioinformatics Scientist @PacBio

[Christos Proukakis @proukakis]

A great resource: tandem repeat database in ⁦@AllofUsResearch⁩ with the expert input of ⁦@PacBio⁩ ⁦@MikeEberle⁩ ⁦@egor_dolzhenko⁩ https://t.co/fRAM7NVHmx

[Matt Holt @holtjma]

If you missed this poster session at #ASHG24, you can now view the poster online! Happy to have a chat if you're interested in long-read PGx with #PacBio!

https://t.co/0rAR1OcChc

[Alexander Hoischen @ahoischen]

Just back from #ashg24 - new record by an automated library prep for a Revio SMRT cell:
8.1 M reads; 133.0 Gb; 16.4 kb avg size;
Q34.
…and this is before upgrade to SPRQ!
Great lab team @GeneticNijmegen @radboudumc!
#RevioOlympics

[Stergachis Lab @stergachislab]

Deaminase-assisted Fiber-seq (DAF-seq) has arrived! DAF-seq is an amplification-compatible version of #Fiberseq that resolves genetic and chromatin architectures with single-nucleotide, single-molecule, single-haplotype, and single-cell precision. https://t.co/ArxOOOlqoj

[AJHG @AJHGNews]

Great talk by Xiao Chen about application of Paraphase in Four Seasons 4. Learn more about the method in last year’s AJHG paper #ASHG24

https://t.co/4ZvZwNGBK4

[Matt Holt @holtjma]

My poster on long read pharmacogenomics with #PacBio HiFi is up for today at #ASHG24. Ping me on here if you want to meet before the poster session!

[Alexander Hoischen @ahoischen]

Great presentation by Joe Devaney from @GeneDx #ASHG2024 #ASHG24.
Long-read genome sequencing are almost ready for prime time! Exciting times ahead!!

[Dr Harriet Dashnow @hdashnow]

Enjoying all the tandem repeat fun at #ASHG24?
The Dashnow lab is hiring software developer/data analyst roles. Apply by Nov 13 for best consideration
https://t.co/6jWSeBlO2t

[Matt Holt @holtjma]

It’s a packed room for Xiao Chen’s talk on resolving paralogous genes with #PacBio HiFi sequencing! #ASHG24

[Mike Eberle @MikeEberle]

Xiao talking now about using Paraphase and HiFi data to resolve segmental duplications genome wide

[Mark Chaisson @mjpchaisson]

There are plenty of opportunities to make calls this weekend. It's time. Any questions for how? dm. Repost so twitter algo sends out.

[PacBio @PacBio]

NEW: Learn how the new SPRQ chemistry for #Revio is improving long-read #sequencing performance and affordability like never before: https://t.co/mgNFywDIcR

#PacBio #ASHG24

[Jon Belyeu @jon_belyeu]

I'm happy to announce that SVTopo, a new computational tool from PacBio (https://t.co/W6sHuB0Ps9), is ready for you to try. SVTopo creates simple images so you can rapidly understand complex changes in genome structure. See me and learn more at ASHG 2024 in Denver, poster 1180W

[PacBio @PacBio]

Don’t miss our #ASHG24 platform talk on genome-wide profiling of highly similar paralogous genes using #HiFisequencing. Learn how this powerful approach is helping unravel complex regions of the genome.

Details: https://t.co/3ZPGVoXPec

#PacBio #Genomics

[Nature Reviews Genetics @NatureRevGenet]

Another #Review highlight: Sequence composition changes in short tandem repeats: heterogeneity, detection, mechanisms and clinical implications https://t.co/PZjcoh7M6k by @IndhuShreeRB, @egor_dolzhenko, @MikeEberle & Jan M. Friedman @UBC @BCCHresearch @PacBio

[Chris Saunders @ctsa11]

We've been making steady usability updates to the sawfish SV caller thanks to user feedback, including a new feature to output all supporting reads for each SV. The latest binary, user guide, and (new) source code release are available on github here:

https://t.co/Sm80gED6HF

[Graham Erwin @grahamserwin]

We're recruiting! Join our lab at Baylor College of Medicine to explore the functional role of repetitive DNA, the final frontier of the human genome. We work on rare neurodegenerative diseases and cancer. Postdoc and tech positions available. https://t.co/QLJPyolMYu 1/7

[Ben Weisburd @benweisburd]

Tandem repeat catalogs directly affect the sensitivity, cost, and accuracy of TR genotyping studies. In this paper, we discuss TR catalogs and share a new catalog of 4.9 million loci https://t.co/2nEmKJpK6n

[Stephan Zuchner, MD, PhD @szuchner]

Towards truly unified genomic diagnostics: HiFi long-read genomes for difficult-to-detect clinically relevant variants | medRxiv ⁦@ahoischen⁩ https://t.co/SL9ztd9I6F

[Armin Töpfer @XLR]

🚀Exciting Opportunity at PacBio!🧬

Passionate about genomics and cutting-edge technology? PacBio is seeking a Senior Staff Engineer (C++/CUDA) in Menlo Park, CA!
Ready to revolutionize DNA sequencing? Apply now!

https://t.co/MEI4fZONrh

#Genomics #CUDA #BFX #PacBio #Jobs