Mark Chaisson

Quantitative and Computational Biology @USC.

[Mark Chaisson @mjpchaisson]

The method can genotype challenging medically relevant genes like SMN and PTEN as well as produce accurate HLA alleles and CYP2D star-alleles. Finally, we were able to use ctyper genotypes to study relative contributions to gene expression among copy-number variable genes.

[Mark Chaisson @mjpchaisson]

Happy to announce our paper on a new genotyping algorithm, ctyper. https://t.co/D9WUK4mln5 . This is amazing work by Walfred Ma, someone you will want to keep on your radar for future contributions to science.

[Mark Chaisson @mjpchaisson]

Some highlights of the method are: Walfred developed a novel mathematical model that enables accurate and rapid alignment-free genotyping of pangenome alleles. Benchmarking shows little bias (HWE), accurate trio inheritance, and near-perfect copy-number estimation.

[Mark Chaisson @mjpchaisson]

Social media is the cancer of our society - Tadej Pogacar

[Mark Chaisson @mjpchaisson]

@AndrewHires @Hoosierflyman OMG I'm so sorry

[Mark Chaisson @mjpchaisson]

Find me.

[Mark Chaisson @mjpchaisson]

Rolled up to fancy restaurant on bike. Please meme

[Mark Chaisson @mjpchaisson]

@sebatlab Which other app? Maybe what does it rhyme with?

[Mark Chaisson @mjpchaisson]

I will be hosting an information session for applicants to the USC Computational Biology and Bioinformatics PhD program, discussing research topics and application strategies. If you are registering with a non-institutional e-mail, please let me know
https://t.co/mw1NX3Fof3

[Mark Chaisson @mjpchaisson]

My first peleton experience was without Bluetooth connection so I assume this dude is trying to sell me on how profitable Bitcoin will be if I buy now

[Dr. Brian O'Roak @TheRealDrOLab]

#ASHG24 #ASHGtrainees Are you interested in #autism and how #mutations impact the development of the brain? Do you❤️ transcription factors and networks? Want to do all the #omics and live in the beautiful #pnw? DM me to discuss a #postdoc @OHSUSOM 🙏 RT

https://t.co/WXQ9INSi4j

[Nicholas Mancuso @nmancuso_]

Thrilled for #ASHG24. Please check out the cool work from our group and collaborations! Lots of exciting methods for large scale analysis of genetic data 😁

[Mark Chaisson @mjpchaisson]

Did an hour of phone banking from LAX. There are still people who need a nudge. For those who are tweeting to their circles about the need to vote, trust me the persuadables didn't see your socials

[Mark Chaisson @mjpchaisson]

To catch up on our lab research at ASHG, you can see Walfred Ma's talk on sequence-resolved CNV genotyping in the Decoding Structural Variation at Scale session Wed 8-9:30 4-season ballroom 1, and Bida Gu's poster on our VNTR motif database 1044T. See you there!

[Daniel MacArthur @dgmacarthur]

Really excited to have this out: a cell type-specific map of the impact of an understudied class of genetic variation (tandem repeats) on gene expression, at serious scale: nearly 1800 people with both WGS and blood scRNA-seq. So much signal!

[Mark Chaisson @mjpchaisson]

@nomad421 @StevenSalzberg1 Phone banking strictly targets swing states

[Mark Chaisson @mjpchaisson]

@nomad421 @StevenSalzberg1 This may sound like hyperbole, but the small fraction of people you talk to care just as much about their future as you do, but consume /far/ less media. Simply explaining the effects of what each candidate has proposed &relate your experience is very convincing

[Mark Chaisson @mjpchaisson]

@nomad421 @StevenSalzberg1 On behalf of the Harris campaign. I’ve closed on literally every undecided voter I’ve talked to, and gotten people to bring out their friends

[Mark Chaisson @mjpchaisson]

@anshulkundaje Right, so you’re going to go sign up for some phone backing shifts?