@Internist_02@SemitalaFred Exact diagnosis is through immunohistochemistry and in RDD as above its S100 (macrophage markers) positive histiocytes and emperipolesis where as in TCRHL it's B Cell markers such as cd20
@PharmXOAB To prevent cardiovascular toxicity (hypotension, bradycardia, arrhythmias) from its propylene glycol solvent. It requires large peripheral or central veins due to high alkalinity, which risks phlebitis, necrosis, or purple glove syndrome with small veins or extravasation