Emma Federico

MD/MPH Student || Loyola Stritch School of Medicine @LoyolaStritch || Parkinson School of Health Sciences and Public Health @LoyolaParkinson

[ABME @ABMEjournal]

Many people with cerebral aneurysms undergo treatment with a device called a flow diverting stent (FDS), but in some cases, the aneurysm doesn't fully heal – and no one knows why.

Probing this mystery, researchers used 3D-printed, patient-specific aneurysm models and applied real-world blood flow simulations to examine the biological response of endothelial cells – the cells lining blood vessels – after FDS placement.

By comparing treated and untreated models, they found that FDS triggers significant changes in gene expression, especially in pathways related to cell growth, protein synthesis, and RNA splicing. These insights point to a strong link between altered blood flow and cellular behavior at the treatment site.

A clearer understanding of this connection could lead to better tools for predicting patient response, tailoring treatment plans, and ultimately improving long-term outcomes for people with cerebral aneurysms.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://t.co/a2kipiAx7B

𝗦𝘁𝘂𝗱𝘆: Endothelial Cell Transcription Modulation in Cerebral Aneurysms After Endovascular Flow Diversion

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: Guilherme Barros, @EmmaFederico11, @pfilli, Pritha Chanana, @_NaokiKaneko, Ying Zheng, Louis J. Kim, and @DrMichaelLevitt

@UW
@UWMedicine
@UWNeurosurgery
@UWRadiology
@UWSANSCenter
@uwengineering
@UWBioE
@ME_at_UW
@fredhutch
@UCLA
@UCLAHealth
@uclaVIR

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: https://t.co/Gyz8DNneUg

[Stritch School of Medicine Loyola Chicago @LoyolaStritch]

As a dual MD/MPH student, Emma Federico has honed her research skills and developed a passion for connecting the dots between patient care and public health. Read more about Emma's determination to combine medicine with systems-level advocacy: https://t.co/menFL6wX4Q

[Campillo Manon @ManonCampillo]

I’m excited to share the latest analysis from our research and build new connections at the #AACR2025. The major part of this research about the Influence of Age on Overall Survival in Patients with #Glioblastoma is leading by James Fahey and I had the pleasure to present it.

[Derek A. Wainwright, Ph.D. @dwainwright_PhD]

Proud of our lab member and M1/MPH medical student Emma Federico for becoming a Fellow of the 'Loyola Stands Against Gun Violence' coalition. This group will help organize the Annual Community Advocacy and Violence Prevention Summit, here: https://t.co/kfNs3tdsuJ

@EmmaFederico11

[Emma Federico @EmmaFederico11]

Excited to share my very first first author publication! Thankful for the mentorship
from @DrMichaelLevitt @UWNeurosurgery and @UWSANSCenter

Incidence and risk factors of post-stroke seizure among ischemic stroke patients @JSCVD2 https://t.co/rBNrrZooRx

[Emma Federico @EmmaFederico11]

Check out our Research Letter in @StrokeAHA_ASA from @UWSANSCenter !

[Stroke AHA/ASA @StrokeAHA_ASA]

🧵#STROKE Research Letter: Spatial transcriptomics might elucidate molecular diversity and expression patterns within cerebral thrombi. They might be differentiated by LAA and CE stroke subtypes, suggesting patterns consistent with the known pathobiology. #AHAJournals

[Stroke AHA/ASA @StrokeAHA_ASA]

Check out the article, "Unveiling Molecular Diversity in Cerebral Thrombi via Spatial Transcriptomics" ⬇️

https://t.co/N9xQiqXDTl

@EmmaFederico11 @uwsomwwami @UWMedicine @WashUNeurosurg @JCVenterInst

[Emma Federico @EmmaFederico11]

Great presentations tonight from the Community Engagement Fellows discussing their projects addressing health equity in Maywood @LoyolaParkinson @CERCLoyola

[Emma Federico @EmmaFederico11]

I am excited to share that this weekend I received my white coat and today was my first day of M1 year at @LoyolaStritch I am very grateful for this opportunity and all the people who helped me get to this point

[Michael Levitt, MD @DrMichaelLevitt]

New from @UWSANSCenter: Aneurysmal endothelial cells demonstrate distinct genetic changes after flow diverting stent treatment. https://t.co/FNEvDXi3lf
@ABMEjournal
Great work #GuilBarros @EmmaFederico11 @pfilli #NaokiKaneko @YingZhe47280253 #LouisKim

[Emma Federico @EmmaFederico11]

Grateful for the opportunity to present today at #AHA24 @UWSANSCenter

[Emma Federico @EmmaFederico11]

Great first day at the International Stroke Conference #ISC24 @UWSANSCenter

[LUC Public Health Programs @lucpubhealth]

Fall 2023 Community Engagement Fellowship receive their certificates of completion from Dr. Mandy Peacock and Project Coordinator, Emma Federico. Community partners: Village of Maywood, Quinn Center of St. Eulalia, Proviso Partners for Health, Dr. Soulakis and Chicago DPH!

[Emma Federico @EmmaFederico11]

Calling all @LoyolaChicago students! The Community Engagement Fellowship @CERCLoyola is a great opportunity to work with community members and promote health equity while addressing the social determinants of health in the Maywood community.

[LUC Public Health Programs @lucpubhealth]

Calling all students!

[LUC Public Health Programs @lucpubhealth]

This week @LoyolaParkinson faculty, staff, and students attended a play hosted by Congo Square Theater on housing justice, and inter-class relationships as it related to families being dislocated from Cabrini-Green.  This was followed by a tour of the former Cabrini-Green.

[Derek A. Wainwright, Ph.D. @dwainwright_PhD]

Lab meeting today by Research Assistant Professor, Dr. Prashant Bommi discussing work on a new approach to therapeutically neutralize immunosuppressive glioblastoma cell IDO1 effects.

@LUNeurosurgery @sitcancer @CancerResearch @NeuroOnc @koolmolecule @LijieZhai @LauingKlau

[Emma Federico @EmmaFederico11]

Very grateful for the past 4 years at the @UWSANSCenter

[Stroke & Applied NeuroScience Center @UWSANSCenter]

We would like to thank @EmmaFederico11 and @alemikgonz for their contributions to the SANS lab. They will be moving forward with their future endeavors as medical/graduate students. We will miss you!

[Michael Levitt, MD @DrMichaelLevitt]

Dr Kate Carroll presenting our pilot work on stroke biomarker discovery at the @UWSurgery @UWCTSurgRes research symposium - great multidisciplinary effort @UWNeurosurgery @UWNeurology @uwgenome @uwlabmedpath @UWSANSCenter @chrisryanburke @mjmaccoss

[UW Neurology @UWNeurology]

The UW Stroke Team visited the Port of Seattle Fire Department yesterday! Dr. Melanie Walker led a training with Stryker to talk about ischemic strokes and demo what its like in the OR to pull out a clot within 24 hours of the stroke.
@local1257 @UWMedicine @UWMedNSI

[Emma Federico @EmmaFederico11]

Check out our paper!
Machine Learning Analysis of the Cerebrovascular Thrombi Lipidome in Acute Ischemic Stroke: @JNN_journal https://t.co/qI8AFzALYK