Cannot express how excited I am that our paper is finally out in real life!
Macrophages contribute to the obesity paradox. We found PD-1 acts directly on macrophages to alter metabolism and suppress their anti-tumor function in obesity associated cancers.
https://t.co/f3JEB1PhLN
It's out! @JackieEBader led our new @TheMarkFdn Endeavor team study showing obesity promotes PD-1 on macrophages to suppress anti-tumor immunity but sensitize to checkpoint therapy--a new mechanism of the cancer "obesity paradox" @VUMC_VCI @VUMC_Cancer
https://t.co/LJiiEalmJv
Very happy that @melissa_m_wolf's paper on how loss of VHL in kidney cancer cells reshapes the tumor immune microenvironment to recruit suppressive macrophages & point to a new immunotherapy target in RCC is out in @jclinicalinvest
@VUMC_Cancer
@VUMC_VCI
https://t.co/Qeut9uyn0Y
We wrote this review to put a metabolic spin on my favorite paper of all time--Martin Raff's 1992 piece in Nature on Social Control of Cell Survival and Death. Nutrients and metabolic signaling hold it all together.
https://t.co/TmZf1n1YGJ
I can’t imagine a better human, scientist, physician, and mentor for the NCI Director! @KimrynRathmell you inspire me everyday, congratulations, you are so deserving! I feel so lucky to have you as my mentor!
https://t.co/jtSfmUikFA
Attending #ACSFall2021 hybrid mtg? Be sure to check out @UArizona faculty including Drs. Jeanne Pemberton & Steven Schwartz. Special S/O to Marissa Trujillo, Erin Jennings, & Dominique Gaffney, @galliganlab researchers who received travel grants to present @AmerChemSociety! 🙌💪
If you are attending @AmerChemSociety next week, be sure to check out ALL THREE of our oral presentations! And a big thank you to @ACS_DivBioChem and @acschemtox for supporting @MarissaNT96@ErinQJennings and Dominique with travel awards!
Hot off the press! SIRT2 is an enzymatic eraser of protein lact(o)ylation. Congrats to @ErinQJennings and @MarissaNT96 and thank you to our wonderful collaborators https://t.co/Fos5n7j0tH
UNIVERSITY OF ARIZONA-Banner and Canpus Health will accept PPE donations. collecting from 3-5 pm TODAY 3/21 in parking lot 2029 by BIO5/Drachman hall/ College of nursing. Please bring anything you can spare: gloves masks of all kinds, gowns, RNA isolation kit. #COVID-19
ugh such a satisfying use of chemistry to show how metabolism elegantly regulates itself. dear @galliganlab, @dgaffney128, and @ErinQJennings -- i love this
https://t.co/qw2BerwE1E
@galliganlab @dgaffney128 @ErinQJennings Huge congrats to the @galliganlab on this elegant work, showing again that non-enzymatic modifications may play greater cellular roles than we think...