Eswarappa Lab IISc

Traversing through the regulation of translation at its start & stop and looking into teeny-tiny tardigrades. PI: @SandeepME_IISc. @iiscbangalore

[Eswarappa Lab IISc @EswarappaLab]

Think the 3'UTR is just a non-coding tail?

Our new preprint shows ribosomes translating a conserved dORF in RPL36A, acting as a bodyguard to protect the mRNA from miRNA-5701 destruction!

https://t.co/JA95F4zGTI

Led by @DebrajManna27

@japi_17, Dhruvi, Kirtana, @SandeepME_IISc

[Kesavardan S @keshu_VRimmCh]

Dried to survive: desiccated tardigrades tolerate high heat
The famously resilient creatures can withstand temperatures of 85 °C if allowed to dry out first.
@SandeepME_IISc
@iiscbangalore
@BICS_IISc
https://t.co/ov40ncAOBl

[Harikumar R Suma @hari_rs_]

Publication alert 📢

Tardigrades really said: “85°C in tun state? Easy peasy lemon squeezy 😎🔥”

How do these tiny water bears survive extreme thermal stress? 🤔
Link: https://t.co/PvQgzuF4bw

#tardigrade #biology #extremotolerance
@Bio_IISc @iiscbangalore

[Harikumar R Suma @hari_rs_]

Our latest study suggests that modulation of thermal conductivity contributes to temperature tolerance in anhydrobiotic tardigrades 🥳

Super happy to be part of this work!!
@SandeepME_IISc @EswarappaLab @DivyaHarishV @nrakhtar3284 @ArindamPhysics
#scicomm

[Eswarappa Lab IISc @EswarappaLab]

#NewPaperAlert
Know that tardigrades can tolerate heat?
Biologists: It’s probably a molecular pathway.
Tardigrades: Have you considered thermodynamics?
Curious? Read our latest: https://t.co/vfNj8vS8Sy
@hari_rs_ @DivyaHarishV @nrakhtar3284 @ArindamPhysics @SandeepME_IISc

[Eswarappa Lab IISc @EswarappaLab]

Curious about what a downstream ORF in MAP3K10 can do? Check out our new preprint describing its regulatory function: https://t.co/kkjQTOAN51
Led by Kirtana Vasu

@swatigh04639837
@Sarthak_Sahoo_ @DebrajManna27 @SaubhikSom @nrakhtar3284
@debaleenak8 @SandeepME_IISc @iiscbangalore

[RIM2026 @RIM2026_IIScBlr]

The stage is set! We warmly welcome all delegates to the 13th RNA India Meeting (RIM 2026) at the Indian Institute of Science, Bangalore.
Starting tomorrow, we embark on three days of rigorous scientific exchange, exploring the latest breakthroughs in RNA biology. 🧬

[RIM2026 @RIM2026_IIScBlr]

⏳ Only a few days left!

Registration for the 13th RNA India Meeting 2026 closes March 31 — that's this Tuesday!

📍 Venue: IISc Bangalore
🎤 Submit abstracts for short talks & posters soon!

🔗 Register now: https://t.co/6a4mDfora6

#RIM2026 #RNAIndia #RNAresearch

[Rajyaguru lab @LabRajyaguru]

Registration deadline: March 31, 2026

[Raj @rajgodhuli]

RNA India Meeting 2026 (RIM2026) will be held at IISc, Bangalore, from April 27-29, 2026. We are super excited to reveal the fantastic line-up of speakers. Registration deadline: March 31. Waiver request deadline-March 25.
Look forward to welcoming the participants in Bangalore!

[Saravanan Palani @syncellbiolab]

How short can a degron be?
We report a 9–aa, genetically encoded, tunable degron that drives MDM2-dependent degradation and enables precise control of endogenous protein levels. Thanks to @EswarappaLab for the opportunity to explore this in yeast.

#Degron #yeast #cellbiology

[Eswarappa Lab IISc @EswarappaLab]

Interested in tunable protein degradation? Check out our new preprint describing a compact, portable degron derived from MTCH2: https://t.co/RFnFb1O1pd
Led by @emlekha

@SaubhikSom @SandeepME_IISc
Great collaboration with @anubhav_dhar @syncellbiolab

@BICS_IISc @iiscbangalore

[Saubhik Som @SaubhikSom]

I will be presenting a poster on my doctoral work on In vivo Significance of Stop Codon Readthrough in MTCH2 from @EswarappaLab at EMBL Conference Protein Synthesis and Translational Control. Please drop by Poster #203 to know more about the work
#EMBLProtein

[IISc Bangalore @iiscbangalore]

IISc faculty Pradipta Biswas & Sandeep M Eswarappa were honoured by ISRO chairman Dr V Narayanan during the felicitation programme for Gaganyatri and Axiom-04 mission team, held in New Delhi on Thursday (Aug 21).
@SandeepME_IISc

[The Biochemical Society @BICS_IISc]

We welcome you all to the colloquium of Ms. Kirtana today. For details, please check below:

[The Biochemical Society @BICS_IISc]

We invite you all to today's colloquium by @SaubhikSom. For details, please check poster :

[The Biochemical Society @BICS_IISc]

Today, we invite you all to attend the colloquium by @DebrajManna27 , For details, please check below:

[Swati Ghosh @swatigh04639837]

A moment of immense pleasure and honor to receive the prestigious Dr R K Maller Memorial Gold Medal for the best performance in coursework in the integrated PhD programme in Biological Sciences, from the honorable Chief Guest of the IISc Convocation 2025 Prof. Manjul Bhargava.

[The Biochemical Society @BICS_IISc]

Today, we welcome you all to attend the symposium by @DebrajManna27 and Kirtana Vasu. For details, check below:

[The Biochemical Society @BICS_IISc]

BICS invites everyone to attend today's symposium. For details, check below: