Genomic Instability and Cancer Lab

PhD Félix Machín (@MachinPhd) Laboratory Official X Account. We do science with yeast and more, especially interested in chromosome stability and cell cycle.

[Genomic Instability and Cancer Lab @FMachinLab]

News! Our eLife Version of Record finally published! https://t.co/scKNIZDKNq
Cohesin’s kleisin subunit is back in late mitosis after DNA double-strand breaks, and…

[Jessel A.Plasencia @Jessel_ap]

Check out our latest work from @FMachinLab, published in @eLife:
“Cohesin reconstitution and homologous recombination repair of DNA double-strand breaks in late mitosis”
https://t.co/sw5C93jZf0

I’d like to especially thank Dr. Lorraine Symington for her invaluable collaboration.

[Instituto de Tecnologías Biomédicas @ITB_ULL]

👇🏻👇🏻👇🏻

[LaPa-ciencia Podcast @LaPa_ciencia]

También te dejamos el primer episodio en @ApplePodcasts, por si prefieres utilizar esta plataforma 🙌🏼

Episodio 1. Temporada 01. Esperanza Hernández Carralero: De la cromatina a la cerámica.

https://t.co/jC7z1gXgBf

#ciencia #podcast #podcastenespañol #science #people

[LaPa-ciencia Podcast @LaPa_ciencia]

Aquí comienza… LaPa-ciencia! 🤩.

Temporada 1. Episodio 01. Esperanza Hernández Carralero: De la cromatina a la cerámica.

Que lo disfruten👇🏼☺️
https://t.co/neRdoEwEH4

#podcast #Podcastenespañol #ciencia #science #historiasreales #people #reallife

[Genomic Instability and Cancer Lab @FMachinLab]

👇🏼

[LaPa-ciencia Podcast @LaPa_ciencia]

Aquí comienza… LaPa-ciencia 🤩https://t.co/dCz8GiTAUG

[Genomic Instability and Cancer Lab @FMachinLab]

A continuation from our previous paper on iScience, we now show that Msc1 maintains nuclear envelope and nuclear pore complex integrity for DNA repair. Msc1 synergistically works with the ESCRT-III complex for this purpose, underscoring NE homeostasis as key to genome stability.

[Genomic Instability and Cancer Lab @FMachinLab]

Delighted to announce that our latest paper is finally out in Commun Biol!
https://t.co/Fc8iMVHaUp

[Genomic Instability and Cancer Lab @FMachinLab]

Closed mitosis is a form of cell division used by pathogenic fungi and protists. In this process, chromosomes are segregated without dismantling the nuclear envelope (NE). But what happens when they undergo mitosis with an excess of NE? Find out here! https://t.co/Ta7dMvI8eV

[Néstor García Rodríguez @NestorGarRod]

POSTDOC position available in my group @cabimer @unisevilla . Please spread the word!
Contact: [email protected]

[Félix Machín, PhD @MachinPhd]

Estoy buscando candidatos para solicitar una beca postdoctoral Juan de la Cierva para trabajar en la relación entre la envoltura nuclear y la inestabilidad del genoma. ¡Date prisa, solo queda una semana pero ya tengo mi parte preparada!

[Félix Machín, PhD @MachinPhd]

I am looking for candidates to apply for a Juan de la Cierva postdoctoral fellowship to work on the link between the nuclear envelope and genome instability. Rush, there is only one week left but I’ve got my part ready!

[Félix Machín, PhD @MachinPhd]

I am pleased to share our latest work as a result of collaborating with chemists to delve into SAR and MOA of drug candidates. This time with the small local biopharma company #CEAMED https://t.co/8Wd7Erh0Lp

[Abraham Acevedo @Acevedo_lab]

Job alert! Se ofrece contrato de doctorado asociado a proyecto (FPI) centrado en el estudio del papel central de TDP-43 en la ELA. Buscamos personas con entusiasmo y ganas de trabajar interesadas en el estudio de mecanismos moleculares de neurodegeneración en modelos de ratón

[Genomic Instability and Cancer Lab @FMachinLab]

After posting our recent discovery of Msc1 as a protein involved in DNA double-strand break repair in late mitosis, we now post a preprint on how Msc1 might work together with the ESCRT-III complex for this goal: https://t.co/ZTzXGl1XxK

[Félix Machín, PhD @MachinPhd]

Glad to share our latest paper!

Msc1 is a nuclear envelope protein that reinforces DNA repair in late mitosis: iScience https://t.co/ZZJHZ1uS1g

... and stay tuned for more soon!

[Genomic Instability and Cancer Lab @FMachinLab]

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[Mariano Hdez @mnhdez]

Mañana jueves 28, a las 9.30 se celebran las XVII Jornadas de Genética de la ULL. Aquellos/as que no puedan asistir podrán seguirlas a través del siguiente enlace https://t.co/frMitxojMx
@CienciaULL @ULL @AsociacionJINTE @PaleogenomicULL @FMachinLab @Gesalud_ULL

[Genomic Instability and Cancer Lab @FMachinLab]

We are pleased to share with you our latest pre-print on the discovery of Msc1 as a late mitotic DNA repair factor in yeast.

https://t.co/ixo2Tpurny

[Genomic Instability and Cancer Lab @FMachinLab]

One question about #Covid19 detection, one objective, straightforward experiments…microPublication Biology. Thanks FIISC for the funding.
Effect of carrier yeast RNAs in the detection of SARS-CoV-2 by RT-LAMP https://t.co/YC71KrlDZv

[Genomic Instability and Cancer Lab @FMachinLab]

Preprint alert ❗️❗️❗️👇🏼 @MachinPhd @Jessel_ap @ITB_ULL @CienciaULL @Columbia

https://t.co/0y4WyiknhI

[Jessel A.Plasencia @Jessel_ap]

Do you know that #Cohesin is involved in DNA repair after chromosome segregation?🧬

Check our new short story 🤩:

“Cohesin still drives homologous recombination repair of DNA double-strand breaks in late mitosis”

@MachinPhd⁩ #LSymington @Columbia⁩ https://t.co/B9WDlZdrB7