Favour Onyeogaziri

Researcher in Vascular Biology focused on cerebral cavernous malformations #CCM @UU_University
| @MagnussonLab

icook |ibake @bakesbyFay

[Favour Onyeogaziri @Faayvour]

Grateful fro conferences like the #VAC2025 @VACure1 that bring scientists and physicians together and remind of the patients who are our reason.

Also, happy international women in Science day🔬🧪🥼👩‍🔬

#rarediseases #vascularmalformations
#cureCCM
#fundCCMresearch

[Favour Onyeogaziri @Faayvour]

I'm pleased to announce that our #NCVR publication has now been released. @MagnussonLab we present the roles of #NETs in the progression of cerebral cavernous malformations (CCM)

Read at: https://t.co/L7187l1mKE
#NETosis #CureCCM #TreatCCM #rarediseases

[ATVB: An AHA Journal @atvbahajournals]

Check out the latest #atvbnet post by Favour Onyeogaziri and Suvi Jauhiainen about multiple roles of #thrombomodulin in maintaining #endothelial #hemostasis and #quiescence.

[ATVB: An AHA Journal @atvbahajournals]

ATVB_net: Thrombomodulin: A multifunctional gatekeeper of the endothelium. @Faayvour @SuviJauhiainen @MagnussonLab @GroupLaakkonen

👉https://t.co/ZrCr2pRFhZ

[Favour Onyeogaziri @Faayvour]

Thanks to patient organizations like @AllianceToCure, more interactions between patients and researchers is now possible.

#fundsciece, support science, support rare disease research like #ccm

7/7

#scicommUU23
#rarediseases

[Favour Onyeogaziri @Faayvour]

Access to patients' biopsies is limited. thus, we use #micemodels and #invitro cell cultures to understand how the #CCM disease occurs.

Check out our recent review to see how far we've come in understanding #CCM

https://t.co/JSYOhvrPE6

6/7

#scicommUU23 #rarediseases

[Favour Onyeogaziri @Faayvour]

The road to finding a cure isn't easy because of the #heterogeneity seen in this disease.

#CCM occurs from different mutations in 3 main genes: CCM1/KRIT1, CCM2, CCM3/PDCD10

Although these mutations result in the same disease, symptoms differ

5/7

#scicommUU23 #rarediseases

[Favour Onyeogaziri @Faayvour]

The only way to treat #CCM is via neurosurgery.
but lesions can occur in sensitive places like the brain stem and then, surgery might not be an option.

Scientists around the world are actively trying to find a cure for this disease

4/7

#scicommUU23 #rarediseases

[Favour Onyeogaziri @Faayvour]

40% of people with #CCM will never develop symptoms, but for the rest (including kids), they'll live their lives with symptoms such as #stroke and #hemorrhages.

In many ways, having CCM is like having a ticking bomb in your brain

3/7

#scicommUU23 #rarediseases

[Favour Onyeogaziri @Faayvour]

#cerebralcavernousmalformations aka #CCM is an #incurable neurovascular disorder affecting about 1:200 people worldwide.

Neurovascular disorder means it affects blood vessels in the #brain and #CNS

2/7

#scicommUU23 #rarediseases

[Favour Onyeogaziri @Faayvour]

Hello, today I'll be telling you about the work we do @MagnussonLab with #cerebralcavernousmalformations @VascBioUpp

1/7

#scicommUU23 #CCM #vascularanomalies