Max-Planck Research Group at MPI for Multidisciplinary Science (@mpi_nat) | Autophagy initiation | Structural biochemistry | Reconstitution | Views are my own.
Thanks to all the authors for their hard work! This work was done by @mpi_nat. We thank @CompBioPhys and Urlaub laboratory for their help, and @dfg_public and @maxplanckpress for funding. Check it out for many more surprises!
Feedforward auto-activation: activated ATG101 subsequently quickly activates non-activated ATG101 molecules to create a positive feedforward reaction and supports the local fast assembly of a key complex in autophagy initiation.
PhD or postdoc position in biochemistry, biophysics & structural biology @FaesenLab! Join the project focusing on the reconstitution and structural-functional characterization of newly identified and purified macromolecular super-complexes. 👇
https://t.co/CcCihxIcNR
PhD or postdoc position in biochemistry, biophysics & structural biology @FaesenLab! Join the project focusing on the reconstitution and structural-functional characterization of newly identified and purified macromolecular super-complexes. 👇
https://t.co/CcCihxIcNR
#PhD, #DnD(?) & #postdoc positions in “theory and methods for non-equilibrium atomistic simulations of complex #biomolecules” – Interested in theoretical and computational #biophysics? Check out the #JobAlert & apply here ⬇️: Shares welcome! #hiring#job
https://t.co/ZJF97wtVnJ
🤔Ever wonder why Atg8 has a C-terminal overhang that is always cleaved? Why conserve it? In this mini piece on @JMolBiol Saskia dives into these questions. Thanks to
@AutophagyAarhus
and Prof. Hofmann for the collaboration!
https://t.co/EE57ujWjmc
Model of the regulation of autophagosome biogenesis by AMPK. @BarnabaCarlo, @DavidGBroadbent, @jenscs83 et al. clarify AMPKs regulatory role in #autophagy and highlight its potential as a therapeutic target to reduce autophagy. https://t.co/P07X43bCNf
#CellMetabolism#Cancer
I am excited to share updated information. FINALLY, our paper has been published in eLife! What happens in autophagosomal maturation? We revealed that autophagosomal membranes become negatively charged by PI4P enrichment during maturation. https://t.co/6xld6TZm20
Eat less to live longer? #Autophagy degrades damaged or toxic cellular material to keep cells in good shape. We discovered how #ATG16L1 shapes phagophores. Our article was published today in @NatureSMB ! thanks to all the authors !! Check it out:
https://t.co/kJddgm4yY1