FaesenLab

Max-Planck Research Group at MPI for Multidisciplinary Science (@mpi_nat) | Autophagy initiation | Structural biochemistry | Reconstitution | Views are my own.

[FaesenLab @FaesenLab]

Thanks to all the authors for their hard work! This work was done by @mpi_nat. We thank @CompBioPhys and Urlaub laboratory for their help, and @dfg_public and @maxplanckpress for funding. Check it out for many more surprises!

[FaesenLab @FaesenLab]

This was a wild ride!

https://t.co/22ald0bP16

see thread below 🧵👇
1/6

[FaesenLab @FaesenLab]

Feedforward auto-activation: activated ATG101 subsequently quickly activates non-activated ATG101 molecules to create a positive feedforward reaction and supports the local fast assembly of a key complex in autophagy initiation.

[biorxiv_biochem @biorxiv_biochem]

Influence of ULK1 activity on the memory of ATG101 auto-activation dynamics https://t.co/bv0yoyzZLs #biorxiv_biochem

[SciencesNetwork @SciencesNetwork]

Influence of ULK1 activity on the memory of ATG101 auto-activation dynamics
https://t.co/hBoHEUumKm

[FaesenLab @FaesenLab]

Waiting for you @StorkLab in spectacular Sorrento... I've had worse views while reading literature in preparation. #EMBOautophagy24

[StorkLab @LabStork]

Heading to Sorrento😊, #EMBOautophagy24

[StorkLab @LabStork]

Heading to Sorrento😊, #EMBOautophagy24

[FaesenLab @FaesenLab]

Do not forget to apply!

[MPI for Multidisciplinary Sciences @mpi_nat]

PhD or postdoc position in biochemistry, biophysics & structural biology @FaesenLab! Join the project focusing on the reconstitution and structural-functional characterization of newly identified and purified macromolecular super-complexes. 👇
https://t.co/CcCihxIcNR

[Ivan Đikić @iDikic2]

Place to be for scientists studying quality control mechanisms in life processes. Impressive line-up of speakers. Thx to @HMWK_Hessen @EnableFrankfurt and @dfg_public @SFB1177.
Students and postdocs are invited to apply for selected talks👍🤗
@goetheuni #ubiquitin #autophagy

[MPI for Multidisciplinary Sciences @mpi_nat]

PhD or postdoc position in biochemistry, biophysics & structural biology @FaesenLab! Join the project focusing on the reconstitution and structural-functional characterization of newly identified and purified macromolecular super-complexes. 👇
https://t.co/CcCihxIcNR

[FaesenLab @FaesenLab]

Link for ad: https://t.co/Tx6RoezKpF

[FaesenLab @FaesenLab]

We are recruiting new labmembers @mpi_nat for DFG funded projects!
#Biochemistry, #biophysics and #structuralbiology on metamorphic proteins and new autophagy initiation super-complexes. #PhDposition #Postdocposition #proteins #sciencejobs
Details: https://t.co/5Kczb5vnyr

[FaesenLab @FaesenLab]

We are recruiting new labmembers @mpi_nat for DFG funded projects!
#Biochemistry, #biophysics and #structuralbiology on metamorphic proteins and new autophagy initiation super-complexes. #PhDposition #Postdocposition #proteins #sciencejobs
Details: https://t.co/5Kczb5vnyr

[MPI for Multidisciplinary Sciences @mpi_nat]

#PhD, #DnD(?) & #postdoc positions in “theory and methods for non-equilibrium atomistic simulations of complex #biomolecules” – Interested in theoretical and computational #biophysics? Check out the #JobAlert & apply here ⬇️: Shares welcome! #hiring #job
https://t.co/ZJF97wtVnJ

[Kraft Lab @KraftLabFR]

🤔Ever wonder why Atg8 has a C-terminal overhang that is always cleaved? Why conserve it? In this mini piece on @JMolBiol Saskia dives into these questions. Thanks to
@AutophagyAarhus
and Prof. Hofmann for the collaboration!
https://t.co/EE57ujWjmc

[Journal of Cell Biology @JCellBiol]

Model of the regulation of autophagosome biogenesis by AMPK. @BarnabaCarlo, @DavidGBroadbent, @jenscs83 et al. clarify AMPKs regulatory role in #autophagy and highlight its potential as a therapeutic target to reduce autophagy. https://t.co/P07X43bCNf

#CellMetabolism #Cancer

[Saori Shinoda @SaoShinoda]

I am excited to share updated information. FINALLY, our paper has been published in eLife! What happens in autophagosomal maturation? We revealed that autophagosomal membranes become negatively charged by PI4P enrichment during maturation. https://t.co/6xld6TZm20

[Wollert Lab @WollertLab]

Eat less to live longer? #Autophagy degrades damaged or toxic cellular material to keep cells in good shape. We discovered how #ATG16L1 shapes phagophores. Our article was published today in @NatureSMB ! thanks to all the authors !! Check it out:
https://t.co/kJddgm4yY1