Steven Fletcher

Assistant Professor at the University of Maryland.
All views expressed here are those of Steven Fletcher.

[Ryan M. Pearson, PhD @RyanMPearson]

Congrats to Andrea and Shruti for winning student STAR awards for their amazing immunomodulation research! SFB regional northeast conference was a big success and thankful for the opportunity to join the programming committee! @A_Cottingham @ShrutiDharmaraj @PharmSci_UMB @umsop

[Steven Fletcher @Fletch_Chem]

@RyanMPearson @umsop @UMBaltimore @PharmSci_UMB Very well deserved!!!

[Ryan M. Pearson, PhD @RyanMPearson]

I am excited to share that I have been promoted to Associate Professor with Tenure at @umsop @UMBaltimore @PharmSci_UMB! I am so grateful to all of my past and present trainees, mentors, colleagues, and collaborators that have contributed immensely to the success of our lab! 👏

[Wiley Chemistry @Wiley_Chemistry]

Drug Development Research is seeking a new Associate Editor to join our editorial team! Experts in medicinal chemistry are most welcome. Help us shape the journal, review manuscripts, and contribute to innovative research.

Apply: https://t.co/AEb3ocKm6e

#EditorialOpportunity

[Alex MacKerell @alex_mackerell]

Announcing the University of Maryland, Baltimore Computer-Aided Drug Design Symposium, Thursday May 25, 2023.

The symposium is designed to facilitate collaborations between the CADD Center at the School of Pharmacy and researcher…https://t.co/bvXCK2QePQ https://t.co/fGXAyWCrSU

[The Deredge Lab @DeredgeLab]

We are currently having a great time at #BPS2023 and of course had to get a lab photo with the beautiful view 😍

[Doctor Who @bbcdoctorwho]

“The show is just beginning…” #DoctorWho returns in 2023 ❤️❤️➕🔷

[Ryan M. Pearson, PhD @RyanMPearson]

Excited to share our recent paper: "Excipient-Free Ionizable Polyester Nanoparticles for Lung-Selective and Innate Immune Cell Plasmid DNA and mRNA Transfection" in @ACS_AMI! Congrats to @AtanuCh58926343 @ShrutiDharmaraj @nhutruong_ @PharmSci_UMB @umsop
https://t.co/FAEKoxw9ez

[University of Maryland School of Pharmacy @umsop]

Congratulations to professor Sarah Michel, PhD, on her appointment as our new chair of the Department of Pharmaceutical Sciences. @PharmSci_UMB https://t.co/WKJjhkYj5A

[Ryan M. Pearson, PhD @RyanMPearson]

I’m looking forward to visiting IA State CBE @ISU_CBE over the next couple days! Thanks to Jing Wang, new Asst Prof and former @UMengineering postdoc colleague for the invitation! I’m grateful for the opportunity to share our lab’s newest work. @PharmSci_UMB

[Ryan M. Pearson, PhD @RyanMPearson]

New HDACi modification improves toxicity profile and prevents organ damage by LPS, while retaining anti-inflammatory properties! In ACS Pharmacology & Translational Science (@ACSBioMed). @nhutruong_ @FletchChemistry @chris_goodis @PharmSci_UMB @umsop https://t.co/8GsSaIshQr

[Steven Fletcher @Fletch_Chem]

By scaffold hopping, we transformed selective MCL-1 inhibitors into dual MCL-1/BCL-xL inhibitors!: https://t.co/BOivmdpJzd @alex_mackerell @PharmSci_UMB

[Ryan M. Pearson, PhD @RyanMPearson]

Something big happened in our group this week! Congratulations to Andrea for passing her comprehensive exam on Tuesday! She is our lab's 4th PhD candidate - @PharmSci_UMB @umsop #immune_engineer

[University of Maryland School of Pharmacy @umsop]

Congratulations to Dr. Peter Swaan, professor and chair of pharmaceutical sciences and associate dean for research and advanced graduate studies, on being named a @UMBaltimore distinguished university professor - the highest faculty honor at UMB! https://t.co/uRLcv23ePV

[Ryan M. Pearson, PhD @RyanMPearson]

Congratulations to Jacob for passing his qualifying exam today! Our lab’s third PhD candidate! Looking forward to watching you progress in your research 🔬 #nanoparticles #immune_engineer @PharmSci_UMB @umsop @UMmedschool

[The Deredge Lab @DeredgeLab]

We are hiring! The Deredge lab is looking for skilled and motivated candidates to join the team as an HDX-MS lab research specialist. The position will involve working and liaising with industry partners. Apply below (Job 220000Y1). Please RT or DM.

https://t.co/7orVrFtyL0

[PharmSci_Maryland @PharmSci_UMB]

Chong and MacKerell use MD simulations and the #SILCS technology to model the FcgRIIIa-FceRIg immune receptor complexes of natural killer (NK) cells to gain molecular insight into NK cell activation through Lck and Syk kinases. 10.1016/j.bbagen.2022.130221 @umsop @alex_mackerell

[PharmSci_Maryland @PharmSci_UMB]

Kognole, Hazel and MacKerell extend the #SILCS technology to RNA showing the potential utility of the method for identifying novel ligand binding sites and facilitating the optimization of drug-like molecules. doi: 10.1021/acs.jctc.2c00381 @umsop @alex_mackerell

[Steven Fletcher @Fletch_Chem]

@umsop @PharmSci_UMB Great partnership with @FletchChemistry and @alex_mackerell as well!

[University of Maryland School of Pharmacy @umsop]

Paul Shapiro, PhD, has teamed up with alumna, Ritu Lal, PhD, CEO of GEn1E Lifesciences, to develop treatments for therapies that address lung diseases, cancers and muscle degeneration. Learn about the chemical compounds discovered by @PharmSci_UMB: https://t.co/aeRb2bbv7A