Francesca Florini

Research Associate at Weill Cornell Medicine in @deitschlab Working on antigenic variation in P. falciparum @fra-florini.bsky.social

[Shaw Sebastian @millseba]

Excited to share our new paper, co-led by Gracyn Buenconsejo and me.

Why did a promising anti-#Cryptosporidium drug fail?

We asked whether the parasite itself might already be genetically prepared to escape treatment.
https://t.co/8vTPcB92hm
#Clofazimine #forwardgenetics

[Francesca Florini @fra_florini]

🚨New paper out 🚨 Excited to see this work from Joe Visone and me published! Here we dissect the molecular mechanisms behind var2csa transcription and translation. Take a look👇
https://t.co/zJvylKaUg5

[Francesca Florini @fra_florini]

If you are searching for a postdoc position or know someone who does, cannot recommend this position enough!

[Shaw Sebastian @millseba]

🚨 Postdoc position 🚨
I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026).

Details & application:
https://t.co/mTuilXGwDX

Please share!! 😊

[Akshay Vishwanatha @agnihotri04]

Stable Core, Shape-Shifting Ends: Malaria parasites are DNA repair ninjas 🧬Our new study shows how they use different repair mechanisms to protect vital genes while rapidly changing their “outer coat” to evade immune system and treatments.​
🔗 Read more: https://t.co/Z2CdneN9SM

[UofG Sii @UofGSii]

🎥 | WATCH | Dr Francesca Florini (@Fra_Florini | @WeillCornell) discusses the immune evasion in malaria using insights from single-cell analysis of Plasmodium falciparum.

The full @WCIPGLASGOW seminar is now available on our @YouTube channel:

📺 https://t.co/lx6J9zBRDa

[Francesca Florini @fra_florini]

It’s been such a wholesome experience to be part of the One Health Research workshop at @WACCBIP_UG! So much interest and dedication from the students, really hope to be back next year.

[WACCBIP @WACCBIP_UG]

The One Health Research workshop ends with a closing ceremony and certificate presentation for the first-year MPhil and PhD students.
Congratulations to all participants for their active engagement and dedication throughout the workshop!
And a big thank you to all the facilitators for their dedication and support in making the workshop a success!

[Francesca Florini @fra_florini]

Preprint Alert 🚨 Check out the latest piece of work from the Deitsch lab, where we characterized the sophisticated molecular layers controlling var2csa expression and antigenic variation in P. falciparum

[bioRxiv Microbiology @biorxiv_micrbio]

The molecular basis of coordinated antigen switching enabling chronic infection by human malaria parasites https://t.co/D8JirZRTgc #biorxiv_micrbio

[WACCBIP @WACCBIP_UG]

Day 3 of our workshop starts with a focus on professional development, with sessions on career paths, funding applications, and travel grants.
Francesca shares her personal journey as a researcher, highlighting key decisions and challenges, while engaging students in a Q\&A on what influenced her career choices.
Prof. Kirk Deitsch followed with an in-depth session on applying for career funding, emphasizing the importance of securing resources for research. He also provided practical guidance on how to write effective emails to potential PIs, and what to include in a strong academic CV.

[parasitesrule @parasitesrule]

Registration and Abstract submission for MPMXXXVI are now open! Abstract submission deadline is June 27th, get yours in quickly. @rmc9z @Deepali_Ravel @omartheharb
🔗https://t.co/aUvNO9lkvt

[Francesca Florini @fra_florini]

So proud of this work finally out! We examined antigenic variation at single-cell level and found a lot of unexpected diversity. Make sure to check it out and, if you are at #BioMalPar this week, don’t miss my talk on Thursday #EMBLMalaria

[Nature Microbiology @NatureMicrobiol]

Out Now! scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidance https://t.co/Gijare7IWW #scRNAseq #transcriptomics #malaria

[Francesca Florini @fra_florini]

Something fun (very much needed these days): the Deitsch and Kirkman labs crushing the CUIMC Team Relay Marathon!

[Akshay Vishwanatha @agnihotri04]

Wondered how malaria parasites 🦠 are able to evade human immune system by increasing the number of virulence genes? We show how deficiencies in DNA 🧬 repair mechanisms specific to core genome and subtelomeric regions enable parasites 🦠 to achieve this.
https://t.co/Xrr4G9Np4l

[Francesca Florini @fra_florini]

#StandUpForScience

[Francesca Florini @fra_florini]

What an awesome opportunity it was to present my work at #EMBLInfectionBiology and connect with so many amazing scientists studying #infectionbiology! Great thanks to @marietabernabeu and the other organizers for giving me this chance

[EMBL Events @EMBLEvents]

Welcome to Day 1️⃣ of #EMBLInfectionBiology!
EMBL Conference 'The next generation in infection biology' is a platform for late-stage postdoctoral scientists to present their work and connect with the leading institutions in #infectionbiology 🧑🏻‍🔬
Two days of exciting fully virtual programme ahead of us 🤩

[Francesca Florini @fra_florini]

Really excited I got the chance to share my work at the #FutureOfMalariaResearch Symposium along with other great early-career researchers

[Johns Hopkins Malaria Research Institute @JHMRImalaria]

Live now: @fra_florini explores how Plasmodium falciparum—the most common and deadliest #malaria parasite—skillfully evades the human immune system.

Understanding its tactics could be key to developing stronger defenses. #FutureofMalariaResearch

[Michelle Obama @MichelleObama]

I have some real concerns about what another Trump presidency means for women in this country — and I wanted to share some of my thoughts. If this resonates with you, send this video to every single person you know and remind them what’s at stake in this election.

[Francesca Florini @fra_florini]

Thrilled to share that I won a Poster Award at #MPM2024! Grateful for the recognition and for all the great discussion on my work! @parasitesrule

[Francesca Florini @fra_florini]

For anyone wondering: he succeeded!

[Francesca Florini @fra_florini]

@DeitschKirk trying hard to assemble his birthday mosquito 🤔

[Jason Sheltzer @JSheltzer]

Another scientist whose work initially didn't get the recognition that it deserved - Victor Ambros was denied tenure at Harvard, even after publishing the seminal work that resulted in him receiving the Nobel Prize today!