Clinicians described the results as “one of the most amazing things I’ve ever seen.” An experimental once-daily oral drug called daraxonrasib has produced unprecedented outcomes in advanced pancreatic cancer, reducing the risk of death by 60% compared to standard chemotherapy.
In the Phase 3 RASolute 302 trial, daraxonrasib, a RAS(ON) multi-selective inhibitor developed by Revolution Medicines, nearly doubled median overall survival from 6.6–6.7 months with chemotherapy to 13.2 months in patients with previously treated metastatic pancreatic ductal adenocarcinoma. The trial, presented as a plenary session at the 2026 ASCO Annual Meeting, triggered a rare standing ovation from oncology experts.
Unlike traditional therapies, daraxonrasib effectively targets multiple KRAS variants and even wild-type RAS, offering broad applicability to the vast majority of pancreatic cancers. The drug was also far better tolerated, with only 1.2% of patients discontinuing treatment due to side effects, compared to 11.2% in the chemotherapy arm.
This represents a major advance for a disease long considered one of the most lethal in oncology. Experts are hailing daraxonrasib as a potential paradigm shift that could transform metastatic pancreatic cancer into a more manageable condition. The FDA has already granted expanded access for eligible patients.
[O’Reilly, E. M., et al. (2026). Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer. New England Journal of Medicine. DOI: 10.1056/NEJMoa2605555]
This zeal can be chanelled differently.
The real consequence of internet scam culture is not just how it ruins our reputation on a global stage, it's that we're losing the battle for the minds of the future work force of our country in thousands, to a crude system like HK.
Atiku Abubakar is correct 💯. It is the major reason we want someone different who will change the story in the North #PeterObiForPresident2023#OBIdient
“In the north, 90% of the people are not in tune to social media”. That’s a big lie, and insult to the people from the north. Come 2023, we are taking back our country. #VoteLabourParty
So Atiku is banking on illiteracy and tribalism to win in 2023.
Tinubu is banking on religion and emi lokan to win.
Peter Obi is banking on competency and his plans for young people. If you are a young person and you don't vote for Peter Obi, you don't love yourself.
It may not happen overnight, but you have to keep speaking victory. Keep calling yourself healthy. Keep declaring your children are mighty in the land. Keep declaring your dreams are coming to pass.
Don’t try to understand everything that happens along the way. God works in mysterious ways. If you’re trying to figure everything out, you’re going to get confused. There are things you’re not supposed to understand; that’s what faith is all about.
Ibadan is a city that embodies the values of openness, diversity and great achievements.
It is a home of Firsts; First indigenous TV station, First University in Nigeria & a people who bore witness to the exploits of iconic nationalists such as Dr. N. Azikiwe & Chief O. Awolowo.