Via Whatsapp. God knows frm where in India, but apparently a 12th standard student dancing at his class’s farewell and saluting his school teachers. Lovely moment when a teacher joins in the dance. Took away all my stress of the day!
ChatGPT + Laptop + Internet + 1 Hour a Day = $250 Daily
Normally, I charge $157 for this guide.
𝐖𝐨𝐫𝐭𝐡 $157, 𝐛𝐮𝐭 𝐟𝐫𝐞𝐞 𝐭𝐨𝐝𝐚𝐲!
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@IndiaPostOffice Article number EF485749844IN was sent to speed post on 10th feb from Patna and still its not reached to destination. Can some one please look into this on top priority. Thank U! 🙏
✅ World Mapping Series : Red Sea
- Red Sea is in news.
Context : US Announces 10-Nation Coalition To Combat Yemen's Houthi Attacks In Red Sea.
- Iran-backed Houthi rebels have escalated attacks on tankers, cargo ships and other vessels in the Red Sea, imperiling a transit route that carries up to 12 percent of global trade.
This video will help you to understand the geography of this region.
Do like and retweet for wider reach😍🔥
✅ Red Sea is in crisis - what is happening and what does it mean for global trade?
- This mind-map will help you to understand all the important bordering countries.
Important places and water bodies:
◦ Bab el Mandeb Strait
———————-
◦Gulf of suez
◦Gulf of Aqaba
◦Gulf of Aden
◦Sinai Peninsula
◦Sharm-Al-Sheikh
———————-
- Countries Bordering Red Sea
- Houthi Rebel Menace
A Thread
🧵
Everyday medicine is about to change Forever!
No, it is important not just for #UPSC
..but for next 50 years of your life! 😮
This is neither a drug nor is it a medicine
This is the story of mRNA
mRNA is a single-stranded-protein-synthesizing RNA
It carries protein from DNA to destination cell
What does mRNA actually do?🤔
m in mRNA is messenger!
Messenger of what?🤔
Messenger carrying code to make proteins
Messenger from whom?🤔
DNA!🧬
How does it function?
When cells are to create new protiens,
they don't seek code from DNA every time
Instead, a copy is created in mRNA which stays in the cell
Okay CSEWhy, how will these mRNAs change medicine?
For this, you need to go to basics
Understand these:
As mRNA protein formation is known to mankind,
In the lab, ANY protein can be
• created
• edited
Not just this, unlike the drugs,
the chemistry of one mRNA is same for all mRNAs😮
..this makes it scalable to make multiple mRNAs at once
All in all:
• It is scalable to make mRNAs
• It is easy to create, edit & reform mRNAs
• They can be personalized for individual needs
Best?😍
Body destroys mRNAs once their purpose is fulfilled!
But CSEWhy, I can't visualize this! Help me with an example, can you?
Oh damn! Absolutely😉
Go back to COVID19 vaccination booth
You get a shot in the arm?
It injects mRNAs in your body
mRNA teaches your body what to 'cook' to save you from corona
After a while, mRNA is 'deleted'
The story does not end here!!!!!!
A new variant? You get a new booster
What does booster do?
Same but for newer antibodies:
Teach -> Help create -> Get destroyed
Okay okay! Now I get a hang of it
But how is it going to 'personalize' medicine?
What are the other use cases?
This is where it gets interesting!
Think of cancer💡
• If you add mRNA to cancer vaccines,
body cells will be guided to make mutated cells
• These mutated cells will find their way to tumor site
BOOM! The immune attack thus 'blasts' the cancerous cells💥
Best? Side effects are lesser as mRNAs are eventually destroyed
Wow, that's a good analogy bro.
But is it not sounding too good to be true?
I mean, tell me the issues, will you?
You are on right page!😁
Biggest challenge is to find the right protein
Then comes the angle of cost!
(personalized medicine won't be cheap, you see?)
Alas! okay.
Where are we headed with mRNA vaccines?
They can prove beneficial in treatment of:
• heart & neuro diseases
• anemia with infusion of blood vessel producing mRNAs
Further, the potential to deal with Auto Immune Diseases (AIDs) is promising!
For those who don't know:
AIDs are where your body starts eliminating its own cells🥺
Eliminations are hard!
Even harder when you could have managed to learn something in time but chose not to!
How to not let this happen with your Current Affairs prep for #UPSC?
Learn with me!🤩
Get most unique insights in an interactive manner
Save both: Time & Money❤️
Follow @CSEWhy💪🏻
@ICICIBank_Care UPI Transaction failed to IRCTC from ICICI Rupay Coral Credit Card but amount is not refunded yet, it's been 7 working days. Please assist. @IRCTCofficial@RailwaySeva
I was at a G20 event recently where PM Modi was a speaker🫡
As he spoke, I took some notes. Once home, I realized there's more that I shall compile for all aspirants📝
Sharing 10 of his Quotes for your #UPSC GS2 IR answers💡
Bookmark this tweet to save to notes🔖
Most people find saying NO extremely difficult. As an IAS officer, I have had to learn this more than most people.
My tips on the 'Art of saying no'
Saying NO is difficult due to:
👉Fear of dissappointing others & need to be likeable
👉Fear of upsetting people & associated stress
👉Fear of conflict/avoiding confrontation
👉Obligation like in family situation
👉Lack of assertiveness: We feel it makes us look rude
Why we need to learn to say NO
👉Boundaries: Important way to establish and maintain healthy boundaries
👉Self: Prioritize your own needs and well-being
👉Prevents burnout and stress
👉Being honest to others: You put out the real you rather than a mask to please people
How to say 'No' effectively
👉 Not a Duty: Do not feel that it is your duty to always say YES. First be comfortable in saying no. The struggle is in your mind. If you are not inernally feeling guilty, then you will come across as confident
👉 Be clear and direct: When you say no, it's important to be clear to avoid any confusion or misunderstanding. Also, be specific about what you are saying no to, and be firm in your decision.
👉 Be polite and respectful: Make it clear that No is to the thing and not to the person. It is not personal against the person. That'll lessen your guilt and any bad feelings in the other
👉 Offer alternatives, if possible: For eg, you can say "I'm sorry, I can't help you with that, but I can do this instead" or "I can't do that , but I can help you find someone who can."
👉 Quality is imp: In office situations, you may feel that saying 'no' will diminish your image, but actually if you always say yes, you will be overburdened and the quality of work will reduce. Only take on work that you can finish with quality
👉 Stand your ground: If the person you are saying no to tries to persuade or pressure you to change your mind, it's important to stand your ground and to reiterate your decision. You can say "I understand that this is important to you, but it is not possible for me to do it"
👉 Don't apologize excessively: It's okay to apologize if you are saying no, but don't over-apologize or make excuses for your decision. You are well within your rights to say no.
By being clear, polite, and firm, you can say no in a way that is respectful and assertive.
It's okay to say no, and it can be an important way to take care of yourself
अपने भीतर एक अनकही कहानी को दबाए रखना - उससे ज़्यादा पीड़ादायक और कुछ नहीं.
-माया एंजेलू - अमीरीकी अश्वेत साहित्यकार महिला
A quote from today's Indianexpress.