Genetic Engineering & Biotechnology News

Serving the biotech industry since 1981.
EIC @johnsterling4; publisher @liebertpub
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[Genetic Engineering & Biotechnology News @GENbio]

Spatial Atlasing: Why Sensitivity Is the Real Frontier

A platform that captures only a fraction of transcripts per cell fails to detect lower-abundance populations that define an atlas’s resolution and utility.

Sponsored by @vizgen_inc
https://t.co/3mX2668rSq

[Genetic Engineering & Biotechnology News @GENbio]

New Antibiotic, Manikomycin, Acts on Novel Ribosomal Target

Researchers discover manikomycin, a novel #antibiotic that kills drug-resistant #bacteria by targeting a previously unknown ribosomal target
@McMasterU
#clinicaldevelopment #drugresistance
https://t.co/Xk27T7QRip

[Genetic Engineering & Biotechnology News @GENbio]

Unlock advanced AAV capsid analysis! Join GEN’s webinar with @uspharmacopeia for expert insights and practical tools. Register free: https://t.co/QHYrrTKwkK #AAV #Biotech #GeneTherapy

[Genetic Engineering & Biotechnology News @GENbio]

Cross-Reactive T Cells Could Point to Broad Vaccines or Treatments for Measles, Nipah Virus

Findings suggest that future #vaccines could activate cross-reactive #Tcells to protect against many dangerous viruses at once
@SetteLab @ljiresearch
#measles
https://t.co/JvunYHle1K

[Genetic Engineering & Biotechnology News @GENbio]

Lilly, Ascidian Launch Up-to-$1.9B RNA Exon Editor Collaboration Targeting Inherited Kidney Diseases

@EliLillyandCo will partner with @AscidianTx to develop RNA exon editors intended to treat inherited #kidneydiseases

#GENEdge #geneticmedicines
https://t.co/bbrqdJMLha

[Genetic Engineering & Biotechnology News @GENbio]

Fulcrum Halts Development of SCD Candidate Pociredir, Sets Strategic Review

@FulcrumTx said it is scrapping its lead pipeline program to develop #pociredir as a treatment for #SCD and launching a “comprehensive” review of strategic alternatives
#GENEdge
https://t.co/u7kB8OhQBy

[Genetic Engineering & Biotechnology News @GENbio]

Bio-IT World Keynote Highlights Collaborative Intelligence in AI-Driven Drug Discovery

The discussion explored requirements for implementing federated learning at scale, including examples of how some models are used
@UduakThomas9861
#AI #drugdevelopment
https://t.co/UByOrB2WXR

[Genetic Engineering & Biotechnology News @GENbio]

Low-Cost, Portable Biotech Tools Improve Access to Bioresearch and Diagnostics

Researchers suggest study is the first to translate cell-free #biomanufacturing from laboratory to real-world use across multiple geographic settings
@UofTPharmacy
#bioresearch
https://t.co/YpXxwvuctT

[Genetic Engineering & Biotechnology News @GENbio]

Unlock the future of antibody expression! Join our free GEN webinar on codon optimization, June 11, with experts Justin Byers & Daniel Lin-Arlow, PhD. Register: https://t.co/EJ6q5yvCGP @AnsaBio #Antibodies #DNA #Biotech

[Genetic Engineering & Biotechnology News @GENbio]

Pfizer, Innovent Ink Up-to-$10.5B+ Cancer Treatment Collaboration

@pfizer and @Innovent_2011 will partner to research and develop 12 early-stage and de novo #antibodies and antibody-drug conjugates designed to treat various cancers

#GENEdge #ADCs
https://t.co/wm93XsVLg0

[Genetic Engineering & Biotechnology News @GENbio]

AI-Powered Pan-Cancer Map Reveals Tertiary Lymphoid Structures

Future studies should investigate whether TLS-informed stratification can guide clinical trial design or therapeutic modulation strategies
@IamLinghua @UTMDAnderson
#AI #immuneresponse #TLS
https://t.co/ihDDG9VERw

[Genetic Engineering & Biotechnology News @GENbio]

Accelerate cancer immunotherapy: From sequence to patient in under 12 months. Join experts from Ottimo Pharma & @AsimovBio on June 4. Register now: https://t.co/NnX63yrSbO #CancerImmunotherapy #Biotech #Webinar

[Genetic Engineering & Biotechnology News @GENbio]

CGT Sector Opts for New Tech for Efficiency and Consistency

CGT developers are opting for innovative, closed manufacturing systems that minimize manual steps and facilitate the flow of data
@autolomous
#GENbioprocessing #celltherapy #genetherapy
https://t.co/jeqGD8eXBc

[Genetic Engineering & Biotechnology News @GENbio]

Open-Source Up- and Downstream Modeling in a Unified Environment

Robust, open-source modeling platform unifies upstream and downstream models and predicts product stability within a single environment
@EuropeVaccine
#GENbioprocessing #vaccine #bioreactor
https://t.co/7JU2S00u14

[Genetic Engineering & Biotechnology News @GENbio]

Oligo Therapy Firms Moving Toward Less Expensive, High Production Methods

Some big pharmaceutical companies are turning to enzymatic ligation from solid-phase techniques for oligonucleotides

#GENbioprocessing #enzymes #oligonucleotides
https://t.co/n9g8UM1p2E

[Kevin Davies @KevinADavies]

.@CNBC anchor Becky Quick is our exclusive guest in next week's "State of Precision Medicine" virtual summit.
Hosted by EIC Damian Doherty @Inside_PM.
Wednesday June 3rd: 11 am ET. Registration is free!
https://t.co/rxDsIO3WKw

[Genetic Engineering & Biotechnology News @GENbio]

Automation and AI Will Drive Next-Gen CAR T Manufacturing

Automation and AI could redefine scalable CAR T manufacturing and accelerate broader patient access worldwide
#eXmoorPharma
#GENbioprocessing #automation #immunecells
https://t.co/UaZ33SssHP

[Genetic Engineering & Biotechnology News @GENbio]

Targeting Metabolic Mechanism Restores Chemotherapy Sensitivity in Ovarian Cancer

The data showed elevated levels of the metabolite αKG improved #DNArepair, and blocking it made #cancercells more sensitive to treatment
@airdlab @TheWistar
#ovariancancer
https://t.co/Mqw6XIQ984

[Genetic Engineering & Biotechnology News @GENbio]

Mark Your Calendar! Digital PCR Playbook: Applications and Challenges Across Research and Clinical Labs

Register for this free webinar sponsored by Countable Labs: https://t.co/etrZfcQVTY

#ClinicalLaboratoryTechnique #DiagnosticImaging #NucleicAcidTherapeutics

[Genetic Engineering & Biotechnology News @GENbio]

Gene Editing at Scale: Clinic Seeks Generalizable Therapies

End-to-end pipelines and regulatory advances aim to expand #geneediting to broad patient populations

@idtdna, @DanaherCorp, @elevatebio, @MassGeneralNews, @AuroraTher, and @MaxCyte_info
#CRISPR
https://t.co/GMhvEOXyXa