The George Pantziarka TP53 Trust

The UK's only organisation for people with Li Fraumeni Syndrome and related conditions

[LFS Association @LFSAssociation]

Families in the DMV area, please join us together with @ChildrensNatl for #LiFraumeni syndrome family education day on April 18. Details/register at https://t.co/39tgkIZXHJ

[OCTO Oxford @OCTO_Oxford]

A MILI Milestone: 40 participants randomised onto the trial!
Thank you to all our recruiting sites for your support of the trial.
@OUHospitals, @GSTTnhs, @CUH_NHS, @nottmhospital, @NHSGrampian, @UHSFT, @Leic_hospital
#TP53 #LiFraumeniSyndrome #LFS

[REMEDi4ALL @REMEDi4ALL]

🎓Since launch, the REMEDi4ALL Digital Academy has become a go-to resource for the drug repurposing community:

📘10 modules
🧠200+ topics
🌍170+ learners from 50+ countries

🔗 https://t.co/eK0HkkjvZ1

[The George Pantziarka TP53 Trust @GP_TP53_Trust]

The #MILI trial is testing metformin for cancer prevention in people with #LiFraumeniSyndrome - if you have any questions we've got an extensive set of FAQs just added to our site: https://t.co/inKE9rMboh

[OCTO Oxford @OCTO_Oxford]

The MILI site team based in Leicester Royal Infirmary speak on what this study means to them.
Find out more about MILI here: https://t.co/OSEOafVtE5
#LFS #TP53 #LiFraumeniSyndrome @Leic_hospital

[OCTO Oxford @OCTO_Oxford]

We’re here! Really excited to hear about advances and opportunities at the CRUK Cancer Prevention Research Conference, which is being co-chaired by OCTO Director @sarah_blagden

[OCTO Oxford @OCTO_Oxford]

Members of the MILI team are attending the 2025 CRUK Cancer Prevention Research Conference this week.

#CRUK #LFS

[LFS Association @LFSAssociation]

Presented at @ASCO this week, @DanaFarber researchers shared findings on whole-body MRI as a crucial test modality for individuals with Li-Fraumeni syndrome.

The prospective cohort study found annual whole-body MRIs contribute substantially to detection of asymptomatic localized cancers among individuals with LFS and should become part of standard care, supported by practice guidelines and covered by insurance.

#lifraumenisyndrome #asco25 #lifraumeni Learn more at https://t.co/7HjqpfeLWQ

[REMEDi4ALL @REMEDi4ALL]

🚨Last chance to apply for the REMEDi4ALL Hackathon!

Join an inspiring, hands-on event to tackle real-world drug repurposing challenges.

📍Montserrat, Barcelona | 6–10 October 2025

Only 1 week left to register – applications close 10 June.

🔗Apply now: https://t.co/EBAIeC5Xdm

[REMEDi4ALL @REMEDi4ALL]

#iDR25 – That’s a wrap!

🌍 300+ joined us in Amsterdam for two days of panels, posters, and powerful discussions on smarter routes to repurposed medicines.

👥 Thanks to our speakers and attendees for your insights, energy & contributions.

📖Highlights: https://t.co/PumBPlbCVy

[The George Pantziarka TP53 Trust @GP_TP53_Trust]

It was a great pleasure to present at #iDR25 - especially about #LiFraumeniSyndrome and the MILI trial - linking drug repurposing as a way to reduce cancer incidence in a genetic predisposition. Thank you to all at @REMEDi4ALL for a fantastic conference

[REMEDi4ALL @REMEDi4ALL]

It's been an amazing first day at #iDR25 exploring how we can unlock the potential of existing drugs for patient benefit. It's the poster presentations now, the #REMEDi4ALL booth is buzzing, and we're all set for Day 2!

[REMEDi4ALL @REMEDi4ALL]

Patient organisations on the panel sharing their experience in repurposing medicines - the hurdles and the path to success. On stage: @CLOVESSyndrome, @Mission_Cure, @GP_TP53_Trust, Volwassenen, Kinderen en Stofwisselingsziekten (VKS) and Lorna Pender.

[OCTO Oxford @OCTO_Oxford]

A MILI Milestone: 30 participants randomised onto the trial!

Thank you to all our recruiting sites for your support of the trial.

@OUHospitals, @GSTTnhs, @CUH_NHS, @nottmhospital, @NHSGrampian, @UHSFT, @Leic_hospital
#TP53 #LiFraumeniSyndrome #LFS

[LFS Association @LFSAssociation]

In partnership with @BostonChildrens and @DanaFarber, the LFSA 5th International Youth Workshop will be held August 15-17, 2025.

A cornerstone of Legacy of Hope, this unique experience for youth with Li-Fraumeni syndrome (LFS) empowers them to make lifelong peer connections. Attendees gain tools to navigate LFS with confidence and enjoy an engaging weekend in Boston filled with education and inspiration, interacting with top researchers, providers and young adult mentors.

LFSA provides hotel accommodation and meals during the program, participants are responsible for their travel. Space is limited, please complete the interest form at https://t.co/L46I9itYOh

[LFS Association @LFSAssociation]

Women with Li-Fraumeni syndrome have a higher risk of developing breast cancer - early detection saves lives. This LFSA Legacy of Hope webinar will focus on breast cancer screening, including why it's important, how it works, risks, who should get screened and types of tests available.

Join Renata Sandoval, MD, MSc, PhD of @hsiriolibanes for "Breast Cancer Screening & LFS" on Monday, April 28, 3:00 PM EST.

Sign up at https://t.co/IacLMVuq6L

[Liz Connolly @DrLizConnolly]

🧬 Genetic Predisposition in Sarcoma

Up to 20% #sarcoma may be assoc. with predisposition genes

In our 📝 we review evidence on genetic predis. & how it may influence Rx decisions & management inc. surgery, radiotherapy, systemic Rx & surveillance

1/4

https://t.co/xLEdL9LLpK

[Bone Cancer Research Trust @BCRT]

We are proud to announce a new co-funded research project with @cclguk 🧪

The study, led by Dr Pardo @imperialcollege, will replicate osteosarcoma cells travelling through the bloodstream to understand how this aggressive bone cancer spreads.

Visit: https://t.co/ONq8U5ZwpA

[The George Pantziarka TP53 Trust @GP_TP53_Trust]

Hot off the press - 'Genetic predisposition in sarcomas: clinical implications and management'. Very happy to have been a co-author of this paper.

https://t.co/f34uMpOl5U