We are excited for the 10th annual @critical_med in a few weeks (9/14-9/16)!🥳
Thrilled to see great representation from our preceptors, including:
💊 @imePharm: Co-director; Role of midodrine for vasopressor weaning
💊 @MehrnazCCPharmD: Empiric ABX for sepsis
@almoskow@BIDMCPharmRes@BIDMC_IM 2/2-Maybe related to pt comorbidities-perhaps we see it earlier/mainly in pts w/DM,CKD,elderly 2/2 they aren’t able to compensate as well for lower aldost. levels (whereas most ppl can maintain K via aldost-independent mechanisms for longer periods of time, ie onset may be later
1/🧵
Did you know that heparin can cause hyperkalemia?
But why would an anticoagulant like heparin increase serum K⁺ levels?
The answer also has a wild implication - that heparin may itself have a diuretic effect...
#medtwitter#tweetorial
@almoskow@BIDMCPharmRes@BIDMC_IM 1/2 Good question!
-Lots of variable data, but seems that altho there's a dose dependent effect with aldosterone inhibition, it can still occur at any dose/duration (I’ve seen reports w/ IV infusions and SQ ppx heparin doses)
- Onset can occur as soon as 1–3 days after heparin