#DAMPsPower!! Excited to share the 💥new 💥 @SciImmunology review that @marcodigioia & I wrote about the immunological activities played by host-derived oxidized lipids in controlling infections & tumorigenesis! https://t.co/qVdppJmsoB
The FDA granted us a further Fast Track designation for our biologic drug atibuclimab (IC14). ST-elevation myocardial infarction - the dreaded "Widow-Maker" - hits ~250,000 new US cases and ~20,000 in Australia each year. We have this tiger by the tail and intend to tame it!
@AbbateAntonio Re the sentence re zilti not causing a paradoxical increase in IL-6, see Dr Ridker's recent reminder: "all assays for IL-6 measure total IL-6 rather than free IL-6. Thus, after (zilti) total IL-6 levels paradoxically increase as levels of biologically active free IL-6 decline.”
📢 New in @NatImmunol!
Researchers led by Dr. @Lo_Zanzi, including Drs. Kautilya Jena and Pengxiang Qu, have shown that targeting antifungal immune receptors with a mannan-based adjuvant boosts the strength, durability, and variant coverage of #mRNAVaccine responses.
📑: https://t.co/n2ui9mRFeo
🎧: https://t.co/bcu0IQ5eXy
A milestone day for clinical trial innovation.
We’re announcing the first real-time clinical trials, where @US_FDA can see data signals and endpoints in real time. A quick explainer:
A great review by Doug Mann of a topic close to our heart (and yours, too). In Defense of Homeostasis: Innate Immunity in Cardiac Injury and Repair - Mann - 2026 - Immunological Reviews - Wiley Online Library
More than thrilled to share that I’ve been promoted to full (tenured) Professor @harvardmed@Harvard. This only happened because of the hard work of many people, but I want to dedicate this promotion to my grandmas, Nonna Maria & Nonna Vevè. A #FirstGen thread 🧵 1/x